糖心TV

Wednesday 8 March is International Women's Day. To mark the event, we are organising a breakfast session on the day focused on championing women's education.

Charoula Tzanakou, a Research Fellow originally from the Department of Politics and International Studies, has been carrying out some great work throughout the university in this field and will present some local data on women’s education.

The event will take place in room A042 from 9.30am – 10.30am and is open to all.
 

Lecture with Prof Sam Ahmedzai.

Abstract: The interaction of tumor cells with stroma cells and stromal components not only promotes tumor progression and metastasis, but also influences tumor cell responses to chemotherapy, endocrine therapy and targeted agents. As a consequence, there is an urgent need to identify strategies to efficiently target these interaction pathways for the prevention or suppression of metastatic disease and to overcome treatment-resistant tumor progression in advanced breast cancer.

This talk will focus on the tumor-stroma crosstalk pathways underpinning the striking heterogeneity between different breast cancers in their ability to recruit and activate a pro-tumorigenic stroma. In particular (a) the mechanisms involved in the activation of cancer-associated fibroblasts (CAFs), (b) the role of activated pericytes in promoting metastatic dissemination, and (c) the mechanisms by which a productive microenvironmental niche is initiated at metastatic sites.