糖心TV

Biography

Prof Leandro Pecchia graduated in Biomedical Engineering in 2005 and received the PhD in Biomedical Engineering and Management of Healthcare Services in 2009 at the University 鈥淔ederico II鈥� of Naples. Since 2013, he joined The University of 糖心TV, UK, where he is Reader of Biomedical Engineering. Since 2014, he directs the Applied Biomedical Signal Processing and Intelligent eHealth Lab (ABSPIE). Dr Pecchia authored more than 100 peer-reviewed papers on journals, books and conferences in the fields of Health Technology Assessment (HTA), Internet of Things and machine learning applied to active and healthy ageing and management of chronic diseases.

Since November 2020, Prof Pecchia is supporting the WHO as Innovation Manager for the PPE pillar of the COVID-19 .

Prof Pecchia is President of the , Secretary General of the , Treasurer of the Clinical Engineering Division (), and former IFMBE Healthcare Technology Assessment Division () Chair (2015-18) and Treasurer (2012-15).

Research Interests

• Medical Device design, manufacturing, assessment and maintenance: Need assessment; Medical device regulatory sciences; risk assessment, clearance and certification; HTA, pricing and procurement of medical devices; Medical device maintenance.
• Artificial Intelligence (AI), machine learning and biomedical signals and data: using wearable sensors and AI methods we observe combination of biosignals reflecting both cardiovascular and nervous system statuses (e.g., HRV, ECG, GSR, temperature, physical activity etc.) and studying how their changes can be used for early detection or prediction of severe events associated to Congestive Hearth Failure (CHF), hypertension, diabetes, cancer, eye diseases, pneumonia, and mental stress..
• Health Technology Assessment (HTA): Evaluation methods for healthcare technologies (including drugs, devices, surgical techniques, medical procedures, healthcare processes); Analytic need analysis and quantification of expert knowledge; Clinical outcome assessment and systematic literature review: network meta-analysis; Risk Assessment for Falls in Elderly.
• Telemedicine: Design, development and assessment of platform for the continuity of care of patients suffering from chronic diseases; Design, development and assessment of Point of Care; HTA of Telemedicine; Stress assessment of family caregiver during Home Monitoring programs; Home Monitoring vs Disease Management Programs: the independent value of ICT to health.

Teaching Interests

The application of Systems thinking perspectives to the impact of healthcare on people, processes, information and organisations

Selected Publications

Journal papers published in 2024

1. Haleem, M. S., Castaldo R, MArtina A., Cisuelo O., Pecchia L, A Self-Attention Deep Neural Network Regressor for Real Time Blood Glucose Estimation in Paediatric Population using Physiological Signals, Biomedical Signal Processing and Controll (accepted)
2. Oronti, I. B. Iadanza, E. Pecchia, L. Hypertension Diagnosis and Management in Africa Using Mobile Phones: A Scoping Review, in IEEE Reviews in Biomedical Engineering, vol. 17, pp. 197-211, 2024,
3. Marius Vignigb茅, Alessia Maccaro, Pedro Checa Rif脿, Davide Piaggio & Leandro Pecchia (2024) Pr茅caution ou pr茅vention? Des responsabilit茅s de la politique et de la soci茅t茅 pendant la gestion de la pand茅mie de COVID-19 au B茅nin, Canadian Journal of Development Studies / Revue canadienne d'茅tudes du d茅veloppement,
4. Di Bidino R, Piaggio D, Iadanza E, et al. OP115 Scoping Meta-Review On Methods Used To Assess Artificial Intelligence-Based Medical Devices For Heart Failure. International Journal of Technology Assessment in Health Care. 2023;39(S1):S32-S32.
5. Davide Piaggio, Rossana Castaldo, Gianluca Garibizzo, Ernesto Iadanza, Leandro Pecchia, A smartphone-based tool for screening diabetic neuropathies: A mHealth and 3D printing approach, Biomedical Signal Processing and Control, Volume 89, 2024, 105807, ISSN 1746-8094,  

Journal papers published in 2023

1. Peschke, L., Gyftopoulos, S., Kapusuzo臒lu, A. Folkvord, F. G眉m眉艧 A臒ca, Y. Kaldoudi, E. Drosatos, G. Ba艧ak Ceylan, N. Pecchia, L. G眉ne艧 Peschke, S. Practices of Knowledge Exchange in the Context of the COVID-19 Pandemic. J Knowl Econ (2023).

2. Di Bidino, R.; Piaggio, D.; Andellini, M.; Merino-Barbancho, B.; Lopez-Perez, L.; Zhu, T.; Raza, Z.; Ni, M.; Morrison, A.; Borsci, S.; Fico, G.; Pecchia, L.; Iadanza, E. Scoping Meta-Review of Methods Used to Assess Artificial Intelligence-Based Medical Devices for Heart Failure. Bioengineering 2023, 10, 1109.

3. Maccaro, A.; Audia, C.; Stokes, K.; Masud, H.; Sekalala, S.; Pecchia, L.; Piaggio, D. Pandemic Preparedness: A Scoping Review of Best and Worst Practices from COVID-19. Healthcare 2023, 11, 2572.

   Gyftopoulos, S., Drosatos, G., Pecchia, L., Fico, G., Kaldoudi, E. (2024). Interaction Between Pharmaceutical Companies and the Public During the COVID-19 Pandemic—A Twitter Analysis. In: Badnjevi膰, A., Gurbeta Pokvi膰, L. (eds) MEDICON鈥�23 and CMBEBIH鈥�23. MEDICON CMBEBIH 2023 2023. IFMBE Proceedings, vol 93. Springer, Cham.

4. Bini, F., Franz貌, M., Maccaro, A. Piaggio, D. Pecchia, L. Marinozzi, F. Is medical device regulatory compliance growing as fast as extended reality to avoid misunderstandings in the future?. Health Technol. 13, 831–842 (2023).

5. Maccaro, A., Pagliara, S.M., Zarro, M. Piaggio, D. Abdulsalami, F. Su, W. Haleem, M. S. Pecchia, L. Ethics and biomedical engineering for well-being: a cocreation study of remote services for monitoring and support. Sci Rep 13, 14322 (2023).

6. Mazzeo, L., Boscarino, T., Falasconi, M. B., Polvi, S., Piemonte, V., & Pecchia, L. (2023). Zeolite Synthesis from Waste Materials for the Medical Field of Oxygen Concentrators: Focus on the African Scenario. Chemical Engineering Transactions, 101, 163-168.

7. Oronti, I. B., Lopez-Perez, L., Piaggio, D., Fico, G., & Pecchia, L. (2023). Effects of home telemonitoring using non-invasive versus conventional approaches on patients affected by congestive heart failure: a systematic literature review and meta-analysis. Health and Technology, 1-21.
8. Haleem, M. S., Ekuban, A., Antonini, A., Pagliara, S., Pecchia, L., & Allocca, C. (2023). Deep-Learning-Driven Techniques for Real-Time Multimodal Health and Physical Data Synthesis. Electronics, 12(9), 1989.
9. Cisuelo, O., Stokes, K., Oronti, I. B., Haleem, M. S., Barber, T. M., Weickert, M. O., ... Pecchia, L & Hattersley, J. (2023). Development of an artificial intelligence system to identify hypoglycaemia via ECG in adults with type 1 diabetes: protocol for data collection under controlled and free-living conditions. BMJ open, 13(4), e067899.
10. Iadanza, E., Pasqua, G., Piaggio, D., Caputo, C., Gherardelli, M., & Pecchia, L. (2023). A robotic arm for safe and accurate control of biomedical equipment during COVID-19. Health and Technology, 13(2), 285-300.
11. Gandah, S., Chiurazzi, M., Domina, I., Dei, N. N., Spreafico, G., di Luzio, F. S., ... Pecchia, L. & Ciuti, G. (2023). An Integrated Sensorized Platform for Environmental Monitoring in Healthcare. IEEE Sensors Letters.
12. de Batlle, J., Ben铆tez, I. D., Moncus铆-Moix, A., Androutsos, O., Angles Barbastro, R., Antonini, A., ... Pecchia, L & Fico, G. (2023). GATEKEEPER鈥檚 Strategy for the Multinational Large-Scale Piloting of an eHealth Platform: Tutorial on How to Identify Relevant Settings and Use Cases. Journal of Medical Internet Research, 25, e42187.
13. Piaggio, D., Zarro, M., Pagliara, S., Andellini, M., Almuhini, A., Maccaro, A., & Pecchia, L. (2023). The use of Smart Environments and Robots for Infection Prevention Control: a systematic literature review. American Journal of Infection Control.
14. Luschi, A., Petraccone, C., Fico, G., Pecchia, L., & Iadanza, E. (2023). Semantic ontologies for complex healthcare structures: a scoping review. IEEE Access.
15. Fernandez-Cervantes, E., Montesinos, L., Gonzalez-Nucamendi, A., & Pecchia, L. (2023). Recurrence quantification analysis of center of pressure trajectories for balance and fall-risk assessment in young and older adults. IEEE transactions on neural systems and rehabilitation engineering, 31, 926-935.
16. Andellini, M., Haleem, S., Angelini, M., Ritrovato, M., Schiaffini, R., Iadanza, E., & Pecchia, L. (2023). Artificial intelligence for non-invasive glycaemic-events detection via ECG in a paediatric population: study protocol. Health and Technology, 13(1), 145-154.

Journal papers published in 2022

1. Moon M, Pecchia L, Velazquez Berumen A, Baller A (2022) Personal protective equipment research and innovation in the context of the World Health Organization COVID-19 R&D Blueprint program, Vol. 50(8): 839-843, Aug 01, 2022,
2. Facciorusso, A., Kovacevic, B., Yang, D., Vilas-Boas, F., Mart铆nez-Moreno, B., Stigliano, S., ... Pecchia, L. & Crin貌, S. F. (2022). Predictors of adverse events after endoscopic ultrasound-guided through-the-needle biopsy of pancreatic cysts: A recursive partitioning analysis. Endoscopy, 54(12), 1158-1168.
3. Federici, C., & Pecchia, L. (2022). Exploring the misalignment on the value of further research between payers and manufacturers. A case study on a novel total artificial heart. Health Economics, 31, 98-115.
4. Maccaro, A., Piaggio, D., Leesurakarn, S., Husen, N., Sekalala, S., Rai, S., & Pecchia, L. (2022). On the universality of medical device regulations: the case of Benin. BMC Health Services Research, 22(1), 1-14.
5. Maccaro A., Piaggio D., Vignigb茅 M., Singl A., Pecchia L., COVID-19 preparedness and social dynamics in a Sub-Saharan Africa country, Benin, Health Promotion International, 2022, 37: 1-12.
6. Maccaro A., Piaggio D. , Oronti I. B. , Vignigb茅 M. , Gbokli A., Hougnihin R., Pecchia L, Social engagement in the fight against COVID-19 in the urban and peri-urban areas of Cotonou (Benin, Sub-Saharan Africa): acceptability of the vaccination and tracking program, Frontiers in Medicine, 9:857890
7. Facciorusso, A., Kovacevic, B., Yang, D., Vilas-Boas, F., Mart铆nez, B., Stigliano, S., ...Pecchia L.,... & Crin贸, S. F. (2022). Predictors of adverse events after endoscopic ultrasound through-the-needle biopsy of pancreatic cysts: a recursive partitioning analysis. Endoscopy, Endoscopy 2022; 54(S 01): S87-S88,
8. De Maria, C., D铆az Lantada, A., J盲ms盲, T., Pecchia L, Ahluwaliaet A. (2022) Biomedical engineering in low- and middle-income settings: analysis of current state, challenges and best practices. Health Technol.
9. Stokes K, Oronti B, Cappuccio FP, Pecchia, (2022) Use of technology to prevent, detect, manage and control hypertension in sub-Saharan Africa: a systematic reviewBMJ Open 2022;12:e058840.
10. Vallefuoco E, Bravaccio C, Gison G, Pecchia L , Pepino A. (2022). Personalized Training via Serious Game to Improve Daily Living Skills in Pediatric Patients with Autism Spectrum Disorder, IEEE Journal of Biomedical and Health Informatics (J-BHI).
11. Allocca, C., Jilali, S., Ail, R., Lee, J., Kim, B., Antonini, A., ..., Pecchia L,... & Fico, G. (2022). Toward a Symbolic AI Approach to the WHO/ACSM Physical Activity & Sedentary Behavior Guidelines. Applied Sciences, 12(4), 1776.
12. Federici, C., & Pecchia, L. (2022). POSB52 Exploring the Misalignment on the Value of Further Research between Payers and Manufacturers: A Case Study on a Novel Total Artificial Heart. Value in Health, 25(1), S70.
13. Williams, E., Piaggio, D., Andellini, M., Pecchia, L. (2022) 3D-printed activated charcoal inlet filters for oxygen concentrators: a circular economy approach. Development Engineering 7 (2022) 100094.  
14. Stokes, K., Castaldo, R., Federici, C., Pagliara, S., Maccaro, A., Cappuccio, F., Fico, G., Salvatore, M., Franzese, M. and Pecchia, L.. (2022) The use of Artificial Intelligence Systems in Diagnosis of Pneumonia via signs and symptoms: a systematic review. Biomedical Signal Processing and Control. Volume 72, Part A, February 2022, 103325,
15. De Micco, F., De Benedictis, A., Fineschi, V., Frati, P., Ciccozzi, M., Pecchia, L., ... & Tambone, V. (2022). From Syndemic Lesson after COVID-19 Pandemic to a 鈥淪ystemic Clinical Risk Management鈥� Proposal in the Perspective of the Ethics of Job Well Done. International Journal of Environmental Research and Public Health, 19(1), 15.

Journal papers published in 2021

1. Celesti, A., De Falco, I., Pecchia, L., & Sannino, G. (2021). Guest Editorial Enabling Technologies for Next Generation Telehealthcare. IEEE Journal of Biomedical and Health Informatics, 25(12), 4240-4242.  
2. Andellini M, Faggiano F, Picardo SG, Testa G, Perrotta D, Bianchi R, Nocchi F, Capussotto C, Bassanelli E, Derrico P, Pirozzi N, Pecchia L, Ritrovato M. Health Technology Assessment of Intensive Care Ventilators for Pediatric Patients. Children (Basel). 2021 Nov 1;8(11):986. doi: 10.3390/children8110986. PMID: 34828698; PMCID: PMC8621341.
3. Maccaro A, Piaggio D, Dodaro CA, Pecchia L (2021) Biomedical engineering and ethics: reflections on medical devices and PPE during the first wave of COVID-19, BMC Medical Ethics, (2021) 22:130
4. Stokes K, Castaldo R, Franzese M, Salvatore M, Fico G, Pokvicd LG, Badnjevice A, Pecchia L ,A machine learning model for supporting symptom-based referral and diagnosis of bronchitis and pneumonia in limited resource settings鈥� (2021), Biocybernetics and Biomedical Engineering, Vol 41, issue 4: 1288-1302;
5. Stokes K, Peltrini R, Bracale U, Trombetta M, Pecchia L, Basoli F, Enhanced medical and community face masks with antimicrobial properties: a systematic review, J. Clin. Med. 2021,10(18), 4066;
6. Federici C, Pecchia L. (2021) Early Health Technology Assessment using the MAFEIP tool. A case study on a wearable device for fall prediction in elderly patients. Health and Technology,
7. Muhammad SH, Castaldo R, Pagliara SM, Petretta M, Salvatore M, Franzese M, Pecchia L, (2021), "Time Adaptive ECG driven Cardiovascular Disease Detector", Biomedical Signal Processing and Control, Vol. 20: 102968,
8. Piaggio D., Castaldo R., Cinelli M., Cinelli S., Maccaro A., Pecchia L., (2021) "A framework for designing medical devices resilient to low-resource settings", Global Health 17, 64 (2021),
9. Piaggio D., Namm G., Melillo P, Simonelli F., Iadanza E., Pecchia L., (2021) Pupillometry via smartphone for low-resource settings, Biocybernetics and Biomedical Engineering,
10. Maccaro A, Piaggio D., Pagliara S., Pecchia L, (2021), The role of ethics in science: a systematic literature review from the first wave of COVID-19, Health and Technology,

11. Martinez-R铆osa E, Montesinosa L, Alfaro-Poncea M, Pecchia L ( 2021), A review of machine learning in hypertension detection and blood pressure estimation based on clinical and physiological data, Biomedical Signal Processing and Control, 68 ,

12. Dimauro G, Bevilacqua V, Pecchia L (2021), Bioelectronic Technologies and Artificial Intelligence for Medical Diagnosis and Healthcare, Electronics, 10(11), 1242.
13. Polisena J. , Andellini M. , Salerno P., Borsci S., Pecchia L. , Iadanza E., (2021) Case Studies on the Use of SentimentAnalysis to Assess the Effectiveness and Safety of Health Technologies. IEEE Access. 9:66043-66051.
14. Komarzynski S, Wreglesworth N I, Griffiths D, Pecchia L, Subbe C P, Hughes S F, Davies E H., Innominato P F, (2021) Embracing Change: Learnings from implementing multidimensional digital remote monitoring in oncology patients at a district general hospital during the COVID-19 pandemic. JCO Clinical Cancer Informatics, 5 : 216-220.
15. Castaldo R, Cavalieri C, Soricelli A, Salvatore M, Pecchia L and Franzese M (2021) Machine learning for prostate cancer diagnosis: a systematic literature review of radiomic and genomic method performance, Journal of Medical Internet Research, Vol 23 (4),
16. Castaldo R., Chappell M. J., Byrne H., Innominato P. F., Hughes S., Pescap猫 A. and Pecchia L. (2021). Detection of melatonin-onset in real settings via wearable sensors and artificial intelligence. A pilot Study. Biomedical Signal Processing and Control, 65, 2021,

Journal papers published in 2020

1. Maccaro, A., Piaggio, D., Dodaro, C. A. and Pecchia, L. (2020). Mental illness in some Sub Saharan African communities: the perspective of Bioethics and transcultural nursing. Medicina e Morale, 69(4), 493-502.
2. Porumb, Mihaela, Iadanza, Ernesto, Massaro, Sebastiano, Pecchia, Leandro (2020) A convolutional neural network approach to detect congestive heart failure. Biomedical Signal Processing and Control, 55,
3. Porumb, Mihaela, Stranges, Saverio, Pescap脿篓, Antonio, Pecchia, Leandro (2020) Precision medicine and artificial intelligence : a pilot study on deep learning for hypoglycemic events detection based on ECG. Scientific Reports, 10 (1),
4. Pecchia L, Piaggio D, Maccaro A, Formisano C, Iadanza E. (2020) The inadequacy of regulatory frameworks in time of crisis and in low-resource settings: personal protective equipment and COVID-19, Health and Technology, 2020,
5. Iadanza E, Goretti F, Sorelli M, Melillo P, Pecchia L, Simonelli F, Gerardelli M (2020), 鈥淎utomatic Detection of Genetic Diseases in Pediatric Age Using Pupillometry鈥�, IEEE Access, 8(1):34949-34961,
6. Medenou M, Ahouandjinou M.H., Piaggio D., Houessouvo R.C., Pecchia L, Jossou T.R, (2020) New intelligent network approach for monitoring physiological parameters: the case of Benin, Health and Technology, https://doi.org/10.1007/s12553-020-00418-5,
7. Marano S., Marano M., Pecchia L., Frontiers in Hemodialysis Part II: Toward Personalized and Optimized Therapy, Biomedical Signal Processing and Control, (2020), Vol. 61,
8. Di Pietro L, Piaggio D, Oronti I, Maccaro A, Houessouvo RC , Medenou D, De Maria C, Pecchia L, Ahluwalia A. (2020) 鈥淎 framework for assessing healthcare facilities in low-resource settings: field studies in Benin and Uganda鈥�, Journal of Medical and Biological Engineering,, Vol. 40,
9. Pirc E, Federici C, Bo拧njak M, Peri膰 B, Reber拧ek M, Pecchia L., et al. (2020), 鈥淓arly cost-effectiveness analysis of electrochemotherapy as a prospect treatment modality for skin melanoma鈥�, Clinical Therapeutics, Vol 42 (8),
10. Porumb M., Corbin G, Hatterslay J, Pecchia L. (2020) "Nocturnal Low Glucose Detection in Healthy, Elderly from one-lead ECG using Convolutional Denoising Autoencoders", Biomedical Signal Processing and Control, Vol. 56,
11. Andellini M., Nocchi F., De Santis S., Bassanelli E.,Ritrovato M, Pecchia L. (2020) Clinical needs and technical requirements for ventilators for COVID-19 treatment critical patients: an evidence-based comparison for adult and pediatric age, Health and Technology,
12. Merola, G., Sciuto, A., Pirozzi, F., Andreuccetti, J., Pignata, G., Corcione, F., ... Pecchia L. & Ceccarelli, G. (2020). Is robotic right colectomy economically sustainable? a multicentre retrospective comparative study and cost analysis. Surgical Endoscopy, Vol 34 (9): 4041-4047.

Projects and Grants

• Leveraging AI based technology to transform the future of health care delivery in Leading Hospitals in Europe (ODIN), Funded by: H2020 , Smart Hosptial and AI call (H2020-DT-2020-1), Project Start Date 01-03-2021 - Project End Date 31-08-2024
• Nocturnal Hypoglycaemia detection via ECG and Artificial Intelligence in diabetic patients, Funded by: Wellcome Trust Translational Partnership, Project Start Date 01-06-2020 - Project End Date 31-03-2022
• GATEKEEPER: Smart living homes – whole interventions demonstrator for people at health and social risks, Funded by: Horizon2020, Project Start Date 01-10-2019 - Project End Date 31-03-2023
• HTA of medical devices relying on AI algorithms, Funded by: private funding , Project Start Date 01-05-2021 - Project End Date 31-12-2021
• Hypoglycaemia detection via ECG and Artificial Intelligence in diabetic patients, Funded by: EPSRC IAA, Project Start Date 01-08-2020 - Project End Date 31-12-2021

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• Covid-19 pandemic Social and Healthcare dynamic impact in Benin, Funded by: 糖心TV Global Research Priority on Health and Technology, Project Start Date 01-05-2020 - Project End Date 31-12-2020

• EPSRC Cyclops Grand Challenge Workshop, Funded by: EPSRC, Project Start Date 01-05-2018 - Project End Date 31-07-2019
• Supporting the harmonisation of regulations on medical devices and medical locations among Sub-Saharan African Regions and Europe, Funded by: CGRF, Project Start Date 03-09-2018 - Project End Date 31-03-2020
• Health Technology Assessment of Medical Devices in low and middle income countries, Funded by: EPSRC IAA, Project Start Date 01-03-2017 - Project End Date 31-03-2020
• European network for innovative uses of EMFs in biomedical applications (EMF-MED) Action BM1309 Funded by: European Cooperation in Science and Technology (COST), Project Start Date 15-11-2013 - Project End Date 14-11-2017
• Sleep quality, Centre-of-Pressure sway and standing hypotension to estimate the risk of falling and predict accidental falls, Funded by: Royal Society, Project Start Date 10-03-2015 - Project End Date 09-03-2016

International Appointments

• Innovation Manager (2020-2023) of the WHO WHE IPC Unit ()
• Secretary General (2022-2025) of the International Federation of Medical and Biological Society ()
• Past-President (2023-2025) of the European Alliance of Medical and Biological Engineering and Science ()
• President (2021-2023) of the European Alliance of Medical and Biological Engineering and Science ()
• Secretary General (2018-2022) of the International Union for Physical and Engineering Sciences in Medicine ()
• Treasurer (2018-20212 of the Clinical Engineering Division of the International Federation of Medical and Biological Society ()

• Chairman (2015-2018) of the Health Technology Assessment Division of the International Federation of Medical and Biological Society ()

• Treasurer (2012-2015) of the Health Technology Assessment Division of the International Federation of Medical and Biological Society ()
• Chairman (2015-2018) of the Public Affair Working Group (PAWG) of the European Alliance for Medical and Biological Engineering ()
• Councillor (2014-2016) of the European Alliance for Medical and Biological Engineering ()