Professor Ioannis Nezis

Professor of Cell Biology

Email: I.Nezis@warwick.ac.uk

Phone: 024 765 50400

Office: B174

Twitter:

Research Clusters

Cells & Development

Microbiology & Infectious Disease

Neuroscience

糖心TV Centres and GRPs

糖心TV Antimicrobial Interdisciplinary Centre (WAMIC)

Tissue Image Analytics (TIA) Centre

Vacancies and Opportunities

Post Docs and PhD students.

Motivated Post Docs and PhD students that want to join the lab are very welcome throughout the year. Please contact Dr Nezis for details.

PhD studentships available through MIBTP-DTC

Research Interests

Autophagy is an evolutionarily conserved catabolic process that involves the degradation of cytoplasmic material through the lysosomal pathway. It is a cellular response in nutrient starvation but it is also responsible for the removal of aggregated proteins, damaged organelles and developmental remodeling. Dysfunction in autophagy has been implicated in an increasing number of diseases from bacterial and viral infections to cancer and more recently in neurodegeneration and other ageing-related diseases. Sequestration and degradation of cytoplasmic material by autophagy can be selective through receptor and adaptor proteins. We are using mammalian cells in vitro and the fruit fly Drosophila melanogaster, as a genetically modifiable model organism to investigate the mechanisms of autophagy and selective autophagy in the context of the physiology of the cell, the system and the living organism. We are particularly interested to study selective autophagy in the context of ageing, neurodegeneration, obesity, infections and tumorigenesis.

Research: Technical Summary

In my group we are interested in the role of autophagy in health and disease. Autophagy is an evolutionarily conserved catabolic process that involves the degradation of cytoplasmic material through the lysosomal pathway. Autophagy is a cellular response in nutrient starvation but it is also responsible for the removal of aggregated proteins, damaged organelles and developmental remodeling. Recent studies have shown that dysfunction in autophagy has been implicated in an increasing number of diseases from bacterial and viral infections to cancer and more recently in neurodegeneration and other ageing-related diseases.

Interestingly, it has been shown that induction of autophagy can increase longevity in multiple animal species. Sequestration and degradation of cytoplasmic material by autophagy can be selective through receptor and adaptor proteins. It is therefore important to identify the proteins required for recognition and targeting of the various autophagic cargo for degradation and to elucidate the role of selective autophagy in normal and pathological conditions, especially at the organismal level. We are using mammalian cells in vitro and the fruit fly Drosophila melanogaster, as a genetically modifiable model organism to investigate the mechanisms of autophagy in the context of the physiology of the cell, the system and the living organism. We have developed several molecular markers for monitoring autophagy in vivo.

The major aims of our research are:

To identify novel selective autophagy receptors and adaptors
To understand the cellular and molecular mechanisms of autophagy during ageing
To elucidate the cellular and molecular mechanisms of autophagy in diseases such as neurodegeneration, obesity, bacterial and viral infections and tumorigenesis

The long term goal of our research is to develop therapeutic strategies for these diseases.

We are studying the function of autophagy genes using a combination of RNAi mediated knock down, targeted gene expression, conditional knock out and we use a wide range of approaches, including confocal microscopy, conventional electron microscopy, immuno-gold electron microscopy, biochemical methods and bioinformatics.

In the media

Article in The Guardian covering Professor Nezis' research in autophagy and links to disease and ageing.

Article in The Times covering Professor Nezis' research in autophagy with links to fasting and wellbeing.

Article in The Guardian covering Professor Nezis' research in autophagy with links to fasting and longevity.

Biography

2020 - : Professor of Cell Biology, School of Life Sciences, University of 糖心TV, UK
2018 - 2020: Reader in Cell Biology, School of Life Sciences, University of 糖心TV, UK
2012 - 2017: Associate Professor of Cell Biology, School of Life Sciences, University of 糖心TV, UK
2009-2012: Assistant Professor of Cell Biology, Department of Biological Applications & Technology, University of Ioannina, Greece
2007-2009: Post-doctoral research fellow in Department of Biochemistry, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
2005-2007: Post-doctoral research fellow in Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Greece
2004-2005: Post-doctoral research fellow in Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, Athens, Greece
2002-2004: National military service, Greece
1998-2002: PhD Thesis, Cell Biology, Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Greece
1993-1997: BSc, Biology, Faculty of Biology, University of Athens, Greece

Publications

Williams, Joshua, Nezis, Ioannis P. and Sagona, Antonia P. (2026) Current Opinion in Microbiology, 89 . 102706. doi: ISSN 1369-5274.

Xia, Jianhua, Chen, Haiqin, Wang, Yuying, Hu, Wenbo, Guo, Kaiyu, Linghu, Qingqing, Guo, Pengchao, Wang, Xin, Xia, Qingyou, Nezis, Ioannis P., Zhao, Ping, Dong, Zhaoming and Zhang, Yan (2025) Autophagy, 21 (11). pp. 2443-2455. doi: ISSN 1554-8627.

Ko艂odziej, Marta, Tsapras, Panagiotis, Cameron, Alexander and Nezis, Ioannis P. (2024) Cells, 13 (22). 1897. doi: ISSN 2073-4409.

Louca, Mamas, Penman, Bridget S., Cameron, Alexander and Nezis, Ioannis P. (2024) In: Nezis, I. P, (ed.) Selective Autophagy. Methods in Molecular Biology, 2845 . New York: Humana, pp. 197-201. ISBN 9781071640661

Rogov, Vladimir V., Nezis, Ioannis P., Tsapras, Panagiotis, Zhang, Hong, Dagdas, Yasin, Noda, Nobuo N., Nakatogawa, Hitoshi, Wirth, Martina, Mouilleron, Stephane, McEwan, David G., Behrends, Christian, Deretic, Vojo, Elazar, Zvulun, Tooze, Sharon A., Dikic, Ivan, Lamark, Trond and Johansen, Terje (2023) Autophagy Reports, 2 (1). 2188523 . doi: ISSN 2769-4127.

Chatzichristofi, Agathangelos, Sagris, Vasileios, Pallaris, Aristos, Eftychiou, Marios, Kalvari, Ioanna, Price, Nicholas, Theodosiou, Theodosios, Iliopoulos, Ioannis, Nezis, Ioannis P. and Promponas, Vasilis J. (2023) Autophagy, 19 (12). pp. 3189-3200. doi: ISSN 1554-8627.

Zhang, Yan and Nezis, Ioannis P. (2022) STAR Protocols, 3 (4). 101830. doi: ISSN 2666-1667.

Jacomin, Anne-Claire, Demeter, Amanda, Gul, Lejla, Lister, Ashleigh, Lipscombe, James, Invernizzi, Rachele, Branchu, Priscilla, Macaulay, Iain, Nezis, I. P. , Kingsley, Robert A., Korcsmaros, Tamas and Hautefort, Isabelle (2022) Frontiers in Cellular and Infection Microbiology, 12 . 834895. doi: ISSN 2235-2988.

Lalo, Ulyana, Nezis, Ioannis P. and Pankratov, Yuriy (2022) International Journal of Molecular Sciences, 23 (16). e9228. doi: ISSN 1422-0067.

Gohel, Raksha, Rahman, Ashrafur, L艖rincz, Peter, Nagy, Anik贸, Csord谩s, G谩bor, Zhang, Yan, Juh谩sz, G谩bor and Nezis, Ioannis P. (2022) Autophagy, 18 (10). pp. 2508-2509. doi: ISSN 1554-8627.

Rahman, Ashrafur, Lorincz, Peter , Gohel, Raksha, Nagy, Aniko , Csordas, Gabor, Zhang, Yan, Juhasz, Gabor and Nezis, Ioannis P. (2022) Cell Reports, 39 (9). 110903. doi: ISSN 2211-1247.

Tsapras, Panagiotis and Nezis, Ioannis P. (2022) Autophagy, 18 (5). pp. 1211-1212. doi: ISSN 1554-8627.

Tsapras, Panagiotis, Petridi, Stavroula, Chan, Selina, Geborys, Marta, Jacomin, Anne-Claire, Sagona, Antonia P., Meier, Pascal and Nezis, Ioannis P. (2022) Cell Reports, 38 (4). 110286. doi: ISSN 2211-1247.

Petridi, Stavroula, Jacomin, Anne-Claire, Bhujabal, Zambarla, Johansen, Terje and Nezis, Ioannis P. (2021) In: Methods in Cell Biology. Elsevier, pp. 13-29. ISBN 9780128244876

Klionsky, Daniel J., Abdelmohsen, Kotb, Abe, Akihisa, Abedin, Md Joynal, Abeliovich, Hagai, Acevedo Arozena, Abraham, Adachi, Hiroaki, Adams, Christopher M., Adams, Peter D, Adeli, Khosrow

(2021) Autophagy, 17 (1). pp. 1-382. doi: ISSN 1554-8627.

Jacomin, Anne-Claire, Gohel, Raksha, Hussain, Zunoon, Varga, Agnes, Maruzs, Tamas, Eddison, Mark, Sica, Margaux, Jain, Ashish, Moffat, Kevin G., Johansen, Terje, Jenny, Andreas, Juhasz, Gabor and Nezis, Ioannis P. (2021) Life Science Alliance, 4 (2). e202000965. doi: ISSN 2575-1077.

Jacomin, Anne-Claire, Petridi, Stavroula, Di Monaco, Marisa and Nezis, Ioannis P. (2020) Autophagy, 16 (9). pp. 1721-1723. doi: ISSN 1554-8627.

Jacomin, Anne-Claire, Petridi, Stavroula, Di Monaco, Marisa, Bhujabal, Zambarlal, Jain, Ashish, Mulakkal, Nitha Charles, Palara, Anthimi , Powell, Emma L., Chung, Bonita, Zampronio, Cleidiane, Jones, Alexandra M., Cameron, Alexander, Johansen, Terje and Nezis, Ioannis P. (2020) Cell Reports, 31 (8). 107695. doi: ISSN 2211-1247.

Sarkar, Sovan, Vaccaro, Maria I. and Nezis, Ioannis P. (2020) Frontiers in Cell and Developmental Biology, 7 . 376. doi: ISSN 2296-634X.

Gohel, Raksha, Kournoutis, Athanasios, Petridi, Stavroula and Nezis, Ioannis P. (2020) International Review of Cell and Molecular Biology, 354 . pp. 63-105. doi: ISSN 1937-6448.

Jacomin, Anne-Claire and Nezis, Ioannis P. (2020) Molecular & Cellular Oncology, 7 (1). 1682309 . doi: ISSN 2372-3556.

Chang, Kai, Kang, Ping, Liu, Ying, Huang, Kerui, Miao, Ting, Taylor, Erika, Sagona, Antonia P., Nezis, Ioannis P., Bodmer, Rolf, Ocorr, Karen and Bai, Hua (2020) Autophagy, 16 (10). pp. 1807-1822. doi: ISSN 1554-8627.

Jacomin, Anne-Claire, Geraki, Kalotina, Tjendana-Tjhin, Vindy, Collingwood, Joanna F. and Nezis, Ioannis P. (2019) Frontiers in Cell and Developmental Biology, 7 . 142 . doi: ISSN 2296-634X.

Jacomin, Anne-Claire, Petridi, Stavroula, DiMonaco, Marisa, Jain, Ashish, Bhujabal, Zambarlal, Mulakkal, Nitha Charles, Palara, Anthimi, Powell, Emma L., Chung, Bonita, Zampronio, Cleidiane G., Jones, Alexandra M., Cameron, Alexander, Johansen, Terje and Nezis, Ioannis P. (2019) Working Paper. Cold Spring Harbor: bioRXiv.

Sudhakar, Padhmanand, Claire-Jacomin, Anne, Hautefort, Isabelle, Samavedam, Siva, Fatemian, Koorosh, Ari, Eszter, Gul, Leila, Demeter, Amanda, Jones, Emily, Korcsmaros, Tamas and Nezis, Ioannis P. (2019) Autophagy, 15 (9). pp. 1620-1633. doi: ISSN 1554-8627.

Tsapras, P., Jacomin, Anne-Claire and Nezis, Ioannis P. (2019) In: Autophagy. Methods in Molecular Biology, 1880 . New York, NY: Humana Press, pp. 643-653. ISBN 9781493988723

Jacomin, Anne-Claire, Gul, Lejla, Sudhakar, Padhmanand, Korcsmaros, Tamas and Nezis, Ioannis P. (2018) Frontiers in Cell and Developmental Biology, 6 . 92. doi: ISSN 2296-634X.

Tusco, Radu, Jacomin, Anne-Claire, Jain, Ashish, Penman, Bridget S., Bowitz Larsen, Kenneth, Johansen, Terje and Nezis, Ioannis P. (2017) Nature Communications, 8 . 1264 . doi: ISSN 2041-1723.

Jacomin, Anne-Claire, Samavedam, Siva, Charles, Hannah and Nezis, Ioannis P. (2017) Autophagy, 13 (10). pp. 1782-1789. doi: ISSN 1554-8627.

Tsapras, Panagiotis and Nezis, Ioannis P. (2017) Cell Death & Differentiation, 24 (8). pp. 1369-1379. doi: ISSN 1350-9047.

Jacomin, Anne-Claire and Nezis, Ioannis P. (2017) In: Turksen, K., (ed.) Autophagy in Differentiation and Tissue Maintenance. Methods in Molecular Biology, 1854 . New York, NY: Humana Press, pp. 147-157. ISBN 9781493987474

Palara, Anthimi, Sagona, Antonia P. and Nezis, Ioannis P. (2016) In: Oogenesis : Methods and Protocols. Methods in Molecular Biology, 1457 . Springer, pp. 105-110. ISBN 9781493937936

Jacomin, Anne-Claire and Nezis, Ioannis P. (2016) In: Oogenesis : Methods and Protocols. Springer, pp. 69-78. ISBN 9781493937936

Jacomin, Anne-Claire, Samavedam, Siva, Promponas, Vasilis and Nezis, Ioannis P. (2016) Autophagy, 12 (10). pp. 1945-1953. doi: ISSN 1554-8627.

Tsapras, Panagiotis , Sagona, Antonia P. and Nezis, Ioannis P. (2016) In: Oogenesis : Methods and Protocols. Methods in Molecular Biology, 1457 . Springer, pp. 97-103. ISBN 9781493937936

Klionsky, Daniel J., Abdelmohsen, Kotb, Abe, Akihisa, Abedin, Md Joynal, Abeliovich, Hagai, Acevedo Arozena, Abraham, Adachi, Hiroaki, Adams, Christopher M., Adams, Peter D, Adeli, Khosrow

(2016) Autophagy, 12 (1). pp. 1-222. doi: ISSN 1554-8627.

Eikenes, 脜smund H., Maler酶d, Lene, Christensen, Anette Lie, Steen, Chlo茅 B., Mathieu, Juliette, Nezis, Ioannis P., Liest酶l, Knut, Huynh, Jean-Ren茅, Stenmark, H. and Haglund, Kaisa (2015) PLoS Genetics, Volume 11 (Number 1). pp. 1-7. Article number e1004904. doi: ISSN 1553-7390.

Nezis, I. P., Vaccaro, Maria I., Devenish, Rodney J. and Juh谩sz, G谩bor (2014) BioMed Research International, Volume 2014 . pp. 1-2. Article number 349623. ISSN 2314-6133 doi:

Mulakkal, Nitha Charles, Nagy, P茅ter, Takats, Szabolcs, Tusco, Radu, Juh谩sz, G谩bor and Nezis, I. P. (2014) BioMed Research International, 2014 . 273473. doi: ISSN 2314-6133.

Kalvari, Ioanna, Tsompanis, Stelios, Mulakkal, Nitha Charles, Osgood, Richard, Johansen, Terje, Nezis, I. P. and Promponas, Vasilis J. (2014) Autophagy, Volume 10 (Number 5). doi: ISSN 1554-8627.

Sagona, Antonia P., Nezis, Ioannis P. and Stenmark, H. (Harald) (2014) BioMed Research International, Volume 2014 . Article number 974393. doi: ISSN 2314-6133.

Eskelinen, Eeva-Liisa , Liton, Paloma B., Nezis, I. P. and Piacentini, Mauro (2013) Autophagy, Volume 9 (Number 10). pp. 1451-1454. doi: ISSN 1554-8627.

Shultz, Sebastian Wolfgang, Brech, Andreas and Nezis, I. P. (2013) In: Bailly, Yannick, (ed.) Autophagy : a double-edged sword : cell survival or death? Croatia: In-Tech. ISBN 9789535110620

Nezis, I. P. (2012) Cells, Volume 1 (Number 3). pp. 248-262. doi: ISSN 2073-4409.

Klionsky, Daniel J., Abdalla, Fabio C., Abeliovich, Hagai, Abraham, Robert T., Acevedo-Arozena, Abraham, Adeli, Khosrow, Agholme, Lotta, Agnello, Maria, Agostinis, Patrizia, Aguirre-Ghiso, Julio A.

(2012) Autophagy, Vol.8 (No.4). pp. 445-544. doi: ISSN 1554-8627.

Nezis, I. P. (2012) International Journal of Cell Biology, Vol. 2012 . pp. 1-9. doi: ISSN 1687-8876.

Nezis, I. P. and Stenmark, H. (Harald) (2012) Antioxidants & Redox Signaling, Vol. 17 (No. 5). pp. 786-793. doi: ISSN 1523-0864.

Bartlett, Bryan J., Isakson, Pauline, Lewerenz, Jan, Sanchez, Heriberto, Kotzebue, Roxanne W., Cumming, Robert C., Harris, Greg L., Nezis, I. P., Schubert, David R., Simonsen, Anne and Finley, Kim D. (2011) Autophagy, Vol. 7 (No. 6). pp. 572-583. doi: ISSN 1554-8627.

Haglund, Kaisa, Nezis, I. P. and Stenmark, H. (Harald) (2011) Communicative & Integrative Biology, Vol. 4 (No. 1). pp. 1-9. doi: ISSN 1942-0889.

Sagona, Antonia P., Nezis, I. P., Bache, Kristi G., Haglund, Kaisa, Bakken, Anne Cathrine, Skotheim, Rolf I. and Stenmark, H. (Harald) (2011) PLoS ONE, Vol. 6 (No. 3). e17086. doi: ISSN 1932-6203.

Nezis, I. P., Sagona, Antonia P., Schink, Kay Oliver and Stenmark, H. (Harald) (2010) Trends in Cell Biology, Volume 20 (Number 11). pp. 642-649. doi: ISSN 0962-8924.

Nezis, I. P., Shravage, Bhupendra V., Sagona, Antonia P., Lamark, Trond, Bjorkoy, G., Johansen, Terje, Rusten, Tor Erik, Brech, Andreas, Baehrecke, Eric H. and Stenmark, H. (Harald) (2010) The Journal of Cell Biology, Vol. 190 (No. 4). pp. 523-531. doi: ISSN 0021-9525.

Malagoli, Davide, Abdalla, Fabio C., Cao, Yang, Feng, Qili, Fujisaki, Kozo, Gregorc, Ales, Matsuo, Tomohide, Nezis, I. P., Papassideri, Issidora S., Sass, Mikl贸s, Silva-Zacarin, Elaine C. M., Tettamanti, Gianluca and Umemiya-Shirafuji, Rika (2010) Autophagy, Vol. 6 (No. 5). pp. 575-588. doi: ISSN 1554-8627.

Nezis, I. P., Shravage, Bhupendra V., Sagona, Antonia P., Johansen, Terje, Baehrecke, Eric H. and Stenmark, H. (Harald) (2010) Autophagy, Vol. 6 (No. 8). pp. 1214-1215. doi: ISSN 1554-8627.

Shimokawa, Noriaki, Haglund, Kaisa, H枚lter, Sabine M, Grabbe, Caroline, Kirkin, Vladimir, Koibuchi, Noriyuki, Schultz, Christian, Rozman, Jan, Hoeller, Daniela, Qiu, Chun-Hong

(2010) The EMBO Journal, Vol. 29 (No. 14). pp. 2421-2432. doi: ISSN 0261-4189.

Haglund, Kaisa, Nezis, I. P., Lemus, Dafne, Grabbe, Caroline, Wesche, J酶rgen, Liest酶l, Knut, Dikic, Ivan, Palmer, Ruth and Stenmark, H. (Harald) (2010) Current Biology, Vol. 20 (No. 10). pp. 944-950. doi: ISSN 09609822.

Nezis, I. P., Sagona, Antonia P., Schink, Kay Oliver and Stenmark, H. (Harald) (2010) Trends in Cell Biology, Vol. 20 (No. 11). pp. 642-649. doi: ISSN 09628924.

Sagona, Antonia P., Nezis, I. P., Pedersen, Nina Marie, Liest酶l, Knut, Poulton, John, Rusten, Tor Erik, Skotheim, Rolf I., Raiborg, Camilla and Stenmark, H. (Harald) (2010) Nature Cell Biology, Vol. 12 (No. 4). pp. 362-371. doi: ISSN 1465-7392.

Vaccari, Thomas, Rusten, Tor Erik, Menut, L., Nezis, I. P., Brech, Andreas, Stenmark, H. (Harald) and Bilder, David (2009) Journal of Cell Science, Volume 122 (Number 14). pp. 2413-2423. doi: ISSN 0021-9533.

Nezis, I. P., Lamark, Trond, Velentzas, Athanassios D., Rusten, Tor Erik, Bj酶rk酶y, Geir, Johansen, Terje, Papassideri, Issidora S., Stravopodis, Dimitrios J., Margaritis, Lukas H., Stenmark, H. (Harald) and Brech, Andreas (2009) Autophagy, Vol. 5 (No. 3). pp. 298-303. doi: ISSN 1554-8627.

Nezis, I. P. and Papassideri, Issidora (2008) Methods in Enzymology, Vol. 451 . pp. 669-683. doi: ISSN 00766879.

Mpakou, Vicky E., Nezis, I. P., Stravopodis, Dimitrios J., Margaritis, Lukas H. and Papassideri, Issidora S. (2008) Autophagy, Vol. 4 (No. 1). pp. 97-100. ISSN 1554-8627.

Nezis, I. P., Simonsen, Anne, Sagona, Antonia P., Finley, Kim D., Gaumer, S., Contamine, D., Rusten, Tor Erik, Stenmark, H. (Harald) and Brech, Andreas (2008) The Journal of Cell Biology, Vol. 180 (No. 6). pp. 1065-1071. doi: ISSN 0021-9525.

Hatziantoniou, Sophia, Nezis, I. P., Margaritis, Lukas H. and Demetzos, Costas (2007) Micron, Volume 38 (Number 8). pp. 777-781. doi: ISSN 0968-4328.

Rusten, Tor Erik, Vaccari, Thomas, Lindmo, Karine, Rodahl, Lina M.W., Nezis, I. P., Sem-Jacobsen, Catherine, Wendler, Franz, Vincent, Jean-Paul, Brech, Andreas, Bilder, David and Stenmark, H. (Harald) (2007) Current Biology, Volume 17 (Number 20). pp. 1817-1825. doi: ISSN 0960-9822.

Panagopoulos, Dimitris J., Chavdoula, Evangelia D., Nezis, I. P. and Margaritis, Lukas H. (2007) Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volume 626 (Number 1-2). pp. 69-78. doi: ISSN 13835718.

Velentzas, Athanassios D., Nezis, I. P., Stravopodis, Dimitrios J., Papassideri, Issidora S. and Margaritis, Lukas H. (2007) Autophagy, Volume 3 (Number 2). pp. 130-132. doi: ISSN 1554-8627.

Velentzas, Athanassios D., Nezis, I. P., Stravopodis, Dimitrios J., Papassideri, Issidora S. and Margaritis, Lukas H. (2007) The International Journal of Developmental Biology, Volume 51 (Number 1). pp. 57-66. doi: ISSN 0214-6282.

Nezis, I. P., Stravopodis, Dimitrios J., Margaritis, Lukas H. and Papassideri, Issidora S. (2006) Differentiation, Volume 74 (Number 6). pp. 293-304. doi: ISSN 0301-4681.

Nezis, I. P., Stravopodis, Dimitrios J., Margaritis, Lukas H. and Papassideri, Issidora S. (2006) Journal of Insect Physiology, Volume 52 (Number 3). pp. 282-290. doi: ISSN 0022-1910.

Nezis, I. P., Stravopodis, Dimitrios J., Margaritis, Lukas H. and Papassideri, Issidora S. (2006) Development, Growth and Differentiation, Volume 48 (Number 3). pp. 189-198. doi: ISSN 0012-1592.

Velentzas, Athanassios D., Nezis, I. P., Stravopodis, Dimitrios J., Papassideri, Issidora S. and Margaritis, Lukas H. (2006) Cell and Tissue Research, Volume 327 (Number 2). pp. 399-414. doi: ISSN 0302-766X.

Nezis, I. P., Stravopodis, Dimitrios J., Margaritis, Lukas H. and Papassideri, Issidora S. (2006) Autophagy, Volume 2 (Number 4). pp. 297-298. doi: ISSN 1554-8627.

Chondrogianni, N., Tzavelas, C., Pemberton, A. J., Nezis, I. P., Rivett, A. J. and Gonos, E. S. (2005) Journal of Biological Chemistry, Volume 280 (Number 12). pp. 11840-11850. doi: ISSN 0021-9258.

Nezis, I. P., Stravopodis, Dimitrios J., Papassideri, Issidora S., Stergiopoulos, Costas and Margaritis, Lukas H. (2005) Cell Motility and the Cytoskeleton, Volume 60 (Number 1). pp. 14-23. doi: ISSN 0886-1544.

Nezis, I. P., Modes, Vassilis, Mpakou, Vicky, Stravopodis, Dimitrios J., Papassideri, Issidora S., Mammali, Ioanna and Margaritis, Lukas H. (2003) Tissue and Cell , Volume 35 (Number 2). pp. 113-119. doi: ISSN 0040-8166.

Nezis, I. P., Stravopodis, Dimitrios, Papassideri, Issidora, Robert-Nicoud, Michel and Margaritis, Lukas (2002) Cell and Tissue Research, Volume 307 (Number 3). pp. 401-409. doi: ISSN 0302-766X.

Sideratou, Zili, Foundis, John, Tsiourvas, Dimitris, Nezis, I. P., Papadimas, Georgios and Paleos, Constantinos M. (2002) Langmuir, Volume 18 (Number 13). pp. 5036-5039. doi: ISSN 0743-7463.

Nezis, I. P., Stravopodis, Dimitrios J. , Papassideri, Issidora S., Robert-Nicoud, Michel and Margaritis, Lukas H. (2000) European Journal of Cell Biology, Volume 79 (Number 9). pp. 610-620. doi: ISSN 0171-9335.

Xanthou, G., Tapinos, N. I., Polihronis, M., Nezis, I. P., Margaritis, L. H. and Moutsopoulos, H. M. (1999) Clinical & Experimental Immunology, Volume 118 (Number 1). pp. 154-163. doi: ISSN 0009-9104.

Research Projects

Title	Funder	Award start	Award end
Deciphering molecular mechanisms of ageing and longevity in a long-lived mutant	BBSCR	01 April 2026	31 March 2029
How does membrane lipid remodelling enable intracellular survival of B. cenocepacia? - BBSRC Standard Grant - September 2022	BBSRC	01 January 2024	31 December 2026
A novel component of protein aggregates regulates ageing	BBSRC	11 February 2022	10 February 2025
A broadly accessible facility microscope to probe nanoscale cellular dynamics by combined live cell super-resolution microscopy and photomanipulation (BBSRC ALERT 2021)	BBSRC	01 August 2022	31 July 2023
What is the function of a protein that controls cytoplasmic self-eating in the nucleus?	Leverhulme Trust	01 July 2017	30 September 2020
Elucidating novel roles of selective autophagy in inflammation during ageing	BBSRC	01 April 2017	30 June 2020
Molecular and Cellular Mechanisms of Selective Autophagy and their relevance to ageing	BBSRC	24 March 2014	23 April 2017
Elucidating the function of a new selective autophagy-associated protein in the regulation of immune signalling in vivo in Drosophila	Wellcome Trust	06 July 2015	05 September 2015

Teaching / Student Supervision