Professor Christopher Dowson
Professor of Microbiology
Email: C.G.Dowson@warwick.ac.uk
Phone: 024 765 23534
Office: IBRB2.24
Dowson webpage
Research Clusters
糖心TV Centres
Health GRP (AMR theme co-lead)
糖心TV Antimicrobial Interdisciplinary Centre (WAMIC)
糖心TV Antimicrobial Screening Facility
Sir Howard Dalton Centre for Translational Mechanistic Enzymology (Co-Director)
Vacancies and Opportunities
For postdoctoral opportunities, and interest in potential collaborations, please contact me at the above email address.
Research Interests
Professor Chris G Dowson has, for many years, examined the emergence and evolution of antibiotic resistance across a wide range of bacteria. His recent focus has been to better understand how penicillin targets bacteria. This began during his postdoctoral time at the University of Sussex, in the laboratory of Professor Spratt (1986-1990) and subsequently with his Lister Institute Centenary Fellowship (1991-1996). He currently holds a personal chair at 糖心TV University and is a past member of the Medical Research Council Infections and Immunity Board. He has established the Sir Howard Dalton Centre HDC for Translational Mechanistic Enzymology, the 糖心TV Antimicrobial Interdisciplinary Centre WAMIC, location of the Medicines Discovery Catapult MDC Laboratory facility at 糖心TV and has been involved with philanthropic research fundraising regionally across 糖心TVshire for the past 16 years with the Medical and Life Sciences Research Fund and the national antibiotic discovery charity Antibiotic Research UK .
Chris' research has been funded by BBSRC, EPSRC, MRC, NIH, Wellcome Trust, smaller charities and industry. It is highly collaborative, involving teams of biologists, chemists, engineers and physicists across universities in the UK SWON Alliance CA, CHN Accelerate CHUNK US, SA , EU, AUS to help drive innovations from this research forward to a commercial outcome, which includes the development and use of high throughput biochemical assays and structural determination using the platform at Diamond Light source and virtual reality to visualise antibiotic: target protein interactions. Industry partners past and present include AstraZeneca, Basilea, , Cubist, LifeArc, Merck, Novartis, Novobiotic, GSK and supported recently in AMR SME engagement with the Medicines Discovery Catapult MDC at 糖心TV and currently the Antimicrobial Screening Facility at 糖心TV. He is currently engaged in the discovery program and helping to develop and influence global AMR discovery policy and training for the next generation of AMR leaders. This has leapt forward with a 拢1.5M donation from the GB Sasakawa Foundation to drive UK-Japan collaboration to tackle AMR. This award will support two policy fellows, one from UKHSA the 'Dame Sally Davies Fellowship' and another NCGM, Tokyo the 'Mr Yasuhisa Shinozaki Fellowship' plus four science programs arising from the GBSF/HDC
Research: Technical Summary
The development of new reagents and new assays are crucial underpinning technologies enabling a multi-target focus to antibiotic discovery, with priorities in peptidoglycan biosynthesis and protein biosynthesis (aminoacyl tRNA synthetases, aaRS). The focus of my research is peptidoglycan biosynthesis as an enduringly attractive target or antibiotic discovery, including the multi-targeting of penicillin-binding proteins and Mur ligases.
I am a Co-Director of the Sir Howard Dalton Centre for Translational Mechanistic Enzymology. The Centre brings takes an interdisciplinary approach to drive innovative solutions for antimicrobial discovery, and build research and training capacity to address the global challenge of antimicrobial resistance:
- Enzymology: Protein production, substrate synthesis, kinetic characterisation, developing probe compounds, assay development, High-throughput screening and inhibitor discovery
- Structural Biology: X-Ray Crystallography, NMR, High Resolution Imaging (Electron Microscopy, Cryo-Electron Microscopy, Light Microscopy
- Computational Modelling: Systems modelling and structure-based modelling to develop mechanistic insights
- Professor in Microbiology, 糖心TV University 2000-
- Reader in Microbiology, 糖心TV University 1996-1999
- Lister Institute (Centenary) Research Fellow, Sussex University 1991-1996
- Postdoctoral Research Fellow, Sussex University 1986- 1990
- PhD Microbiology, Bath University 1987
- BSc (hons) Applied Biology, Bath University 1982
Sugita, Yayoi, Dowson, Amanda J., Kajisa, Ichiro, Takechi, Katsuaki, E., Yilan, Zhao, Jingzhi, Wang, Jiaqi, Lin, Xiaofei, Diaz鈥怱aez, Laura, Lloyd, Adrian J., Dowson, Christopher G. and Takano, Hiroyoshi (2025) The Plant Journal, 124 (5). e70588. doi: ISSN 0960-7412.
Rowland, Catherine E., Newman, Hector, Martin, Tazmin T., Dods, Rachel, Bournakas, Nikolaos, Wagstaff, James M., Lewis, Nick, Stanway, Steven J., Balmforth, Matthew, Kessler, Celia, van Rietschoten, Katerine, Bellini, Dom, Roper, David I., Lloyd, Adrian J., Dowson, Christopher G., Skynner, Michael J., Beswick, Paul and Dawson, Michael J. (2025) Communications Biology, 8 (1). 819. doi: ISSN 2399-3642.
Micelli, Carmina, Dai, Yunfei, Raustad, Nicole, Isberg, Ralph R., Dowson, Christopher G., Lloyd, Adrian J., Geisinger, Edward, Crow, Allister and Roper, David I. (2023) Proceedings of the National Academy of Sciences of the United States of America, 120 (8). e2215237120. doi: ISSN 0027-8424.
Stefanini, Irene, Stoakes, Emily, Wu, Houdini H. T., Xu-McCrae, Li, Hussain, Abid, Moat, John, Dowson, Christopher G., David, Miruna D. and Constantinidou, Chrystala (2022) Microbiology Spectrum, 10 (6). e01827-22. doi: ISSN 2165-0497.
Dowson, Amanda J., Lloyd, Adrian J., Cuming, Andrew C., Roper, David I., Frigerio, Lorenzo and Dowson, Christopher G. (2022) Plant Physiology, 190 (1). pp. 165-179. doi: ISSN 1532-2548.
Ghionis, A., Barker, T. and Dowson, Christopher G. (2022) Coventry: University of 糖心TV.
Cama, J., Leszczynski, R., Tang, P. K., Khalid, A., Lok, V., Dowson, Christopher G. and Ebata, A. (2021) ACS Infectious Diseases, 7 (8). pp. 2029-2042. doi: ISSN 2373-8227.
Newman, Hector, Krajnc, Alen, Bellini, Dom, Eyermann, Charles J., Boyle, Grant A., Paterson, Neil G., McAuley, Katherine E., Lesniak, Robert, Gangar, Mukesh, von Delft, Frank, Brem, J眉rgen, Chibale, Kelly, Schofield, Christopher J. and Dowson, Christopher G. (2021) Journal of Medicinal Chemistry, 64 (15). pp. 11379-11394. doi: ISSN 0022-2623.
York, Anna, Lloyd, Adrian J., del Genio, Charo I., Shearer, Jonathan, Hinxman, Karen, Fritz, Konstantin, F眉l枚p, Vilmos, Dowson, Christopher G., Khalid, Syma and Roper, David I. (2021) Structure, 29 (7). pp. 731-742. doi: ISSN 0969-2126.
Klug, Dana M., Idiris, Fahima I. M., Blaskovich, Mark A. T., von Delft, Frank, Dowson, Christopher G., Kirchhelle, Claas, Roberts, Adam P., Singer, Andrew C. and Todd, Matthew H. (2021) Wellcome Open Research, 6 . 146. doi: ISSN 2398-502X.
Aggarwal, Surya D. , Lloyd, Adrian J., Yerneni, Saigopalakrishna S., Narciso, Ana Rita, Shepherd, Jennifer, Roper, David I., Dowson, Christopher G., Filipe, Sergio R and Hiller, N Luisa (2021) Proceedings of the National Academy of Sciences of the United States of America, 118 (14). e2018089118. doi: ISSN 0027-8424.
Styles, Kathryn, Thummeepak, Rapee, Leungtongkam, Udomluk, Smith, Sophie, Christie, Gabrielle S., Millard, Andrew D., Moat, John, Dowson, Christopher G., Wellington, Elizabeth M. H., Sitthisak, Sutthirat and Sagona, Antonia P. (2020) Antibiotics, 9 (4). 200. doi: ISSN 2079-6382.
Jacques, Laura C., Panagiotou, Stavros, Baltazar, Murielle, Senghore, Madikay, Khandaker, Shadia, Xu, Rong, Bricio-Moreno, Laura, Yang, Marie, Dowson, Christopher G., Everett, Dean B., Neill, Daniel R. and Kadioglu, Aras (2020) Nature Communications, 11 (1). 1892 . doi: ISSN 2041-1723.
Catherwood, Anita C., Lloyd, Adrian J., Tod, Julie A., Chauhan, Smita, Slade, Susan E., Walkowiak, Grzegorz P., Galley, Nicola F., Punekar, Avinash S., Smart, Katie, Rea, Dean, Evans, Neil D., Chappell, Michael J., Roper, David I. and Dowson, Christopher G. (2020) Journal of the American Chemical Society, 142 (11). pp. 5034-5048. doi: ISSN 0002-7863.
Cain, Ricky, Salimraj, Ramya, Punekar, Avinash S., Bellini, Dom, Fishwick, Colin W. G., Czaplewski, Lloyd, Scott, David J., Harris, Gemma, Dowson, Christopher G., Lloyd, Adrian J. and Roper, David I. (2019) Journal of Medicinal Chemistry, 62 (21). pp. 9703-9717. doi: ISSN 0022-2623.
Bellini, Dom, Koekemoer, Lizb茅, Newman, Hector and Dowson, Christopher G. (2019) Journal of Molecular Biology, 431 (18). pp. 3501-3519. doi: ISSN 0022-2836.
Hind, Charlotte K., Dowson, Christopher G., Sutton, J. Mark, Jackson, Thomas, Clifford, Melanie, Garner, R. Colin and Czaplewski, Lloyd (2019) Antimicrobial Agents and Chemotherapy, 63 . e00769. doi: ISSN 0066-4804.
Hu, Qingfeng, Yu, Yan, Gu, Dongshi, Xie, Li, Chen, Xingrou, Xu, Ning, Ruan, Jennifer Jin, Dowson, Christopher G. and Ruan, Benfang Helen (2019) ACS Infectious Diseases, 5 (7). pp. 1252-1263. doi: ISSN 2373-8227.
Massarweh, Ahmad, Bosco, Michael, Chantret, Isabelle, L茅ger, Thibaut, Jamal, Layla, Roper, David I., Dowson, Christopher G., Busca, Patricia, Bouhss, Ahmed, Gravier-Pelletier, Christine and Moore, Stuart E. H. (2019) Molecules, 24 (11). 2135. doi: ISSN 1420-3049.
Langley, Gareth W., Cain, Ricky, Tyrrell, Jonathan M., Hinchliffe, Philip, Calvopi帽a, Karina, Tooke, Catherine L., Widlake, Emma, Dowson, Christopher G., Spencer, James, Walsh, Timothy R., Schofield, Christopher J. and Brem, J眉rgen (2019) Bioorganic & Medicinal Chemistry Letters, 29 (15). pp. 1981-1984. doi: ISSN 0960-894X.
Dougan, Gordon, Dowson, Chris and Overington, John (2019) In: Next Generation Antibiotic Discovery Symposium, Jan 2018. Published in: Drug Discovery Today, 24 (2). pp. 452-461. doi: ISSN 1359-6446.
脰ster, Carl, Walkowiak, Grzegorz P., Hughes, Dallas E., Spoering, Amy L., Peoples, Aaron J., Catherwood, Anita C., Tod, Julie A., Lloyd, Adrian J., Herrmann, Torsten, Lewis, Kim, Dowson, Christopher G. and Lewandowski, J贸zef R. (2018) Chemical Science, 9 (47). pp. 8850-8859. doi: ISSN 2041-6520.
脰ster, Carl, Walkowiak, Grzegorz P., Hughes, Dallas E., Spoering, Amy L., Peoples, Aaron J., Catherwood, Anita C., Tod, Julie A., Lloyd, Adrian J., Herrmann, Torsten, Lewis, Kim, Dowson, Christopher G. and Lewandowski, J贸zef R. (2018) [Dataset]
Chen, Feng, Moat, John, McFeely, Daniel, Clarkson, Guy J., Hands-Portman, Ian J., Furner-Pardoe, Jessica P., Harrison, Freya, Dowson, Christopher G. and Sadler, P. J. (2018) Journal of Medicinal Chemistry, 61 (16). pp. 7330-7344. doi: ISSN 1520-4804.
Chen, Feng, Moat, John, McFeely, Daniel, Clarkson, Guy J., Hands-Portman, Ian, Furner-Pardoe, Jessica P., Harrison, Freya, Dowson, Christopher G. and Sadler, P. J. (2018) [Dataset]
Punekar, Avinash S., Samsudin, Firdaus, Lloyd, Adrian J., Dowson, Christopher G., Scott, David J., Khalid, Syma and Roper, David I. (2018) The Cell Surface, 2 . pp. 54-66. doi: ISSN 2468-2330.
Ratamero, Erick Martins, Bellini, Dom, Dowson, Christopher G. and R枚mer, Rudolf A. (2018) Journal of Computer-Aided Molecular Design, 32 (6). pp. 703-709. doi: ISSN 1573-4951.
Hrast, Martina, Juki膷, Marko, Patin, Delphine, Tod, Julie, Dowson, Christopher G., Roper, David I., Barreteau, H茅l猫ne and Gobec, Stanislav (2018) Chemical Biology & Drug Design, 91 (6). pp. 1101-1112. doi: ISSN 1747-0285.
Batson, Sarah, de Chiara, Cesira, Majce, Vita, Lloyd, Adrian J., Gobec, Stanislav, Rea, Dean, F眉l枚p, Vilmos, Thoroughgood, Christopher W., Simmons, Katie J., Dowson, Christopher G., Fishwick, Colin W. G., de Carvalho, Luiz Pedro S. and Roper, David I. (2017) Nature Communications, 8 (1). 1939 . doi: ISSN 2041-1723.
Sychantha, David, Jones, Carys S., Little, Dustin J., Moynihan, Patrick J., Robinson, Howard, Galley, Nicola F., Roper, David I., Dowson, Christopher G., Howell, P. Lynne and Clarke, Anthony J. (2017) PLOS Pathogens, 13 (10). e1006667. doi: ISSN 1553-7374.
Kuroki, Agn猫s, Sangwan, Parveen, Qu, Yue, Peltier, Raoul, Sanchez-Cano, Carlos, Moat, John, Dowson, Christopher G., Williams, Elizabeth G. L., Locock, Katherine E. S., Hartlieb, Matthias and Perrier, S茅bastien (2017) ACS Applied Materials & Interfaces, 9 (46). pp. 40117-40126. doi: ISSN 1944-8244.
Tran, Anh T., Watson, Emma E., Pujari, Venugopal, Conroy, Trent, Dowman, Luke J., Giltrap, Andrew M., Pang, Angel, Wong, Weng-Ruh, Linington, Roger G., Saunders, Jessica, Charman, Susan A., West, Nicholas P., Bugg, Tim, Tod, Julie, Dowson, Christopher G., Roper, David I., Crick, Dean C., Britton, 糖心TV J. and Payne, Richard J. (2017) Nature Communications, 8 . 14414 . doi: ISSN 2041-1723.
Vajs, Jure, Proud, Conor, Brozovic, Anamaria, Gazvoda, Martin, Lloyd, Adrian J., Roper, David I., Osmak, Maja, Ko拧mrlj, Janez and Dowson, Christopher G. (2017) European Journal of Medicinal Chemistry, 127 . pp. 223-234. doi: ISSN 0223-5234.
Nelson, E Andrea, Wright-Hughes, Alexandra, Brown, Sarah, Lipsky, Benjamin A, Backhouse, Michael, Bhogal, Moninder, Ndosi, Mwidimi, Reynolds, Catherine, Sykes, Gill, Dowson, Christopher G., Edmonds, Michael, Vowden, Peter, Jude, Edward B., Dickie, Tom and Nixon, Jane (2016) Health Technology Assessment, 20 (82). doi: ISSN 1366-5278.
Dowson, Christopher G. and O鈥橰eilly, Steven (2016) European Journal of Cell Biology, 95 (9). pp. 323-330. doi: ISSN 0171-9335.
Ara煤jo, Carlos Leonardo de A., Dias, Larissa M., Veras, Adonney A. O., Alves, Jorianne T. C., Cavalcante, Ana L铆dia Q., Dowson, Christopher G., Azevedo, Vasco, Ramos, Rommel T. J., Silva, Artur and Carneiro, Adriana R. (2016) Genome Announcements, 4 (2). e00176. doi: ISSN 2169-8287.
Usha, Veeraraghavan, Lloyd, Adrian J., Roper, David I., Dowson, Christopher G., Kozlov, Guennadi, Gehring, Kalle, Chauhan, Smita, Imam, Hasan T., Blindauer, Claudia A. and Besra, Gurdyal S. (2016) Scientific Reports, 6 . 23191. doi: ISSN 2045-2322.
Smith, Nichola A., Zhang, Pingyu, Greenough, Simon E., Horbury, Michael D., Clarkson, Guy J., McFeely, Daniel, Habtemariam, Abraha, Salassa, Luca, Stavros, Vasilios G., Dowson, Christopher G. and Sadler, P. J. (2016) Chemical Science, 8 (1). pp. 395-404. doi: ISSN 2041-6520.
Lloyd, Adrian J., Potter, Nicola J., Fishwick, Colin W. G., Roper, David I. and Dowson, Christopher G. (2013) ACS Chemical Biology, 8 (10). pp. 2157-2163. doi: ISSN 1554-8929.
Lloyd, Adrian J., Potter, Nicola J., Fishwick, Colin W. G., Roper, David I. and Dowson, Christopher G. (2013) ACS Chemical Biology, 8 (10). pp. 2157-2163. doi: ISSN 1554-8929.
Rushton, Laura, Sass, Andrea, Baldwin, Adam, Dowson, Christopher G., Donoghue, Denise and Mahenthiralingam, Eshwar (2013) Antimicrobial Agents and Chemotherapy, 57 (7). pp. 2972-2980. doi: ISSN 0066-4804.
Dobrzanska, Dorota A., Cooper, A. (Amy), Dowson, Christopher G., Evans, Stephen D., Fox, David J., Johnson, Benjamin R., Biggs, Caroline I., Randev, Rajan, Stec, Helena M., Taylor, Paul C. and Marsh, Andrew (2013) Langmuir, Volume 29 (Number 9). pp. 2961-2970. doi: ISSN 0743-7463.
Castro, Thiago L. P., Seyffert, Nubia, Ramos, Rommel T. J., Barbosa, Silvanira, Carvalho, Rodrigo D. O., Pinto, Anne Cybelle, Carneiro, Adriana Ribeiro, Silva, Wanderson Marques, Pacheco, Luis G. C., Downson, Christopher G., Schneider, Maria P. C., Miyoshi, Anderson, Azevedo, V. (Vasco) and Silva, Artur (2013) Microbial Biotechnology, Volume 6 (Number 2). pp. 168-177. doi: ISSN 1751-7907.
Ruane, Karen M., Lloyd, Adrian J., F眉l枚p, Vilmos, Dowson, Christopher G., Barreteau, H茅l猫ne, Boniface, Audrey, Dementin, S茅bastien, Blanot, Didier, Mengin-Lecreulx, Dominique, Gobec, Stanislav, Dessen, Andr茅a and Roper, David I. (2013) Journal of Biological Chemistry, Volume 288 (Number 46). Article number 33439. doi: ISSN 0021-9258.
Viguetti, S. Z., Pacheco, L. G. C., Santos, L. S., Soares, S. C., Bolt, F., Baldwin, Adam, Dowson, Christopher G., Rosso, M. L., Guiso, N., Miyoshi, A., Hirata, R., Mattos-Guaraldi, A. L. and Azevedo, V. (2012) Epidemiology and Infection, Volume 140 (Number 4). pp. 617-620. doi: ISSN 0950-2688.
Dobrzanska, Dorota A., Cooper, Amy L., Dowson, Christopher G., Evans, Stephen D., Haynes, Tommy, Johnson, Benjamin R. G., Stec, Helena M., Taylor, Paul C. and Marsh, Andrew (2012) Langmuir . (Submitted)
Pacheco, Luis G. C., Castro, Thiago L. P., Carvalho, Rodrigo D. O., Moraes, Pablo M., Dorella, Fernanda A., Carvalho, Nat谩lia B., Slade, Susan E., Scrivens, James H., Feelisch, Martin, Meyer, Roberto, Miyoshi, Anderson, Oliveira, S茅rgio C., Dowson, Christopher G. and Azevedo, Vasco (2012) Frontiers in Microbiology, Volume 3 . Article number 126. doi: ISSN 1664-302X.
McDowell, A. (Andrew), Gao, Anna, Barnard, E. (Emma), Fink, Colin, Murray, Philip I., Dowson, Christopher G., Nagy, I. (Istv谩n), Lambert, Peter A. and Patrick, Sheila (2011) Microbiology, Vol.157 (No.7). pp. 1990-2003. doi: ISSN 1350-0872.
Pacheco, Luis G. C., Slade, Susan E., Seyffert, N煤bia, Santos, Anderson R., Castro, Thiago L. P., Silva, Wanderson M., Santos, Agenor V., Santos, Simone G., Farias, Luiz M., Carvalho, Maria A. R., Pimenta, Adriano M. C., Meyer, Roberto, Silva, Artur, Scrivens, James H., Oliveira, S茅rgio C., Miyoshi, Anderson, Dowson, Christopher G. and Azevedo, Vasco (2011) BMC Microbiology, Vol.11 . article no. 12. doi: ISSN 1471-2180.
Bugg, Tim, Braddick, Darren, Dowson, Christopher G. and Roper, David I. (2011) Trends in Biotechnology, Vol.29 (No.4). pp. 167-173. doi: ISSN 0167-7799.
Hattersley, John G., P茅rez-Vel谩zquez, J., Chappell, M. J. (Michael J.), Bearup, Daniel James, Roper, David I., Dowson, Christopher G., Bugg, Tim and Evans, Neil D. (2011) Computer Methods and Programs in Biomedicine, Vol.104 (No.2). pp. 70-80. doi: ISSN 01692607.
Aaron, Shawn D., Vandemheen, Katherine L., Ramotar, Karam, Giesbrecht-Lewis, Tracy, Tullis, Elizabeth, Freitag, Andreas, Paterson, Nigel, Jackson, Mary, Lougheed, M. Diane, Dowson, Christopher G., Kumar, Vijay, Ferris, Wendy, Chan, Francis, Doucette, Steve and Fergusson, Dean (2010) JAMA: The Journal of the American Medical Association, Vol.304 (No.19). pp. 2145-2153. doi: ISSN 0098-7484.
Bolt, Frances, Cassiday, Pamela, Tondella, Maria Lucia, DeZoysa, Aruni, Efstratiou, Androulla, Sing, Andreas, Zasada, Aleksandra, Bernard, Kathryn, Guiso, Nicole, Badell, Edgar, Rosso, Marie-Laure, Baldwin, Adam and Dowson, Christopher G. (2010) Journal of Clinical Microbiology, Vol.48 (No.11). pp. 4177-4185. doi: ISSN 0095-1137.
Hall, Aron J., Cassiday, Pamela K., Bernard, Kathryn A., Bolt, Frances, Steigerwalt, Arnold G., Bixler, Danae, Pawloski, Lucia C., Whitney, Anne M., Iwaki, M., Baldwin, Adam, Dowson, Christopher G., Komiya, Takako, Takahashi, Motohide, Hinrikson, Hans P. and Tondella, Maria L. (2010) Emerging Infectious Diseases , Vol.16 (No.4). doi: ISSN 1080-6059.
Drevinek, Pavel, Baldwin, Adam, Lindenburg, Laurens, Joshi, Lovleen Tina, Marchbank, Angela, Vosahlikova, Sarka, Dowson, Christopher G. and Mahenthiralingam, Eshwar (2010) Journal of Clinical Microbiology, Vol.48 (No.1). pp. 34-40. doi: ISSN 0095-1137.
Waine, David J., Honeybourne, David, Smith, E. Grace, Whitehouse, Joanna L. and Dowson, Christopher G. (2009) Journal of Clinical Microbiology, Vol.47 (No.11). pp. 3444-3448. doi: ISSN 0095-1137.
Dumville, J. C., Worthy, G., Soares, M. O., Bland, J. M., Cullum, N., Dowson, Christopher G., Iglesias, C., McCaughan, D., Mitchell, J. L., Nelson, E. A. and Torgerson, D. J. (2009) Health Technology Assessment, Vol.13 (No.55). p. 1. ISSN 1366-5278 doi:
Baldwin, Adam, Loughlin, Michael, Dr., Caubilla-Barron, Juncal, Kucerova, Eva, Manning, Georgina, Dowson, Christopher G. and Forsythe, S. J. (Steve J.) (2009) BMC Microbiology, Vol.9 (Article 223). doi: ISSN 1471-2180.
Bearup, Daniel James, Evans, Neil D., Dowson, Christopher G. and Chappell, M. J. (Michael J.) (2009) In: The 9th International Conference on Systems Biology (ICSB2008), Gothenburg, Sweden, Aug 22-28, 2008. Published in: 9th International Conference on Systems Biology 2008 (ICSB 2008): Abstract Book
Spilker, Theodore, Baldwin, Adam, Bumford, Amy, Dowson, Christopher G., Mahenthiralingam, Eshwar and LiPuma, John J. (2009) Journal of Clinical Microbiology, Vol.47 (No.8). pp. 2607-2610. doi: ISSN 0095-1137.
Paradis-Bleau, Catherine, Lloyd, Adrian, Sanschagrin, Francois, Maaroufi, Halim, Clarke, Thomas B., Blewett, Ann, Dowson, Christopher G., Roper, David I., Bugg, Tim and Levesque, Roger C. (2009) Biochemical Journal, Vol.421 (No. 2). pp. 263-272. doi: ISSN 0264-6021.
Bernard, K., Schindle, S., Burdz, T., Wiebe, D., Reimer, A., Dowson, Christopher G., Bolt, F. and Baldwin, Adam (2009) In: 26th International Congress of Chemotherapy and Infection, Toronto, Canada, June 18-21, 2009. Published in: International Journal of Antimicrobial Agents, Vol.34 (Suppl. 2). S11-S11. doi: ISSN 0924-8579.
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2009) Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. doi: ISSN 0968-0896.
Clarke, Thomas B., Kawai, Fumihiro, Park, Sam-Yong, Tame, Jeremy R. H., Dowson, Christopher G. and Roper, David I. (2009) Biochemistry, Vol.48 (No.12). pp. 2675-2683. doi: ISSN 0006-2960.
VenUS II Team (Including: Dumville, Jo C., Worthy, Gill, Bland, J. Martin, Cullum, Nicky, Dowson, Christopher G., Iglesias, Cynthia, Mitchell, Joanne L., Nelson, E. Andrea, Soares, Marta O. and Torgerson, David J.). (2009) British Medical Journal, Vol.338 . Article no. b773. doi: ISSN 0959-8146.
Rose, Helen, Baldwin, Adam, Dowson, Christopher G. and Mahenthiralingam, Eshwar (2009) Journal of Antimicrobial Chemotherapy, Vol.63 (No.3). pp. 502-510. doi: ISSN 0305-7453.
Ward, Philip N., Holden, Matthew T. G., Leigh, James A., Lennard, Nicola, Bignell, Alexandra, Barron, Andy, Clark, Louise, Quail, Michael A., Woodward, John, Barrell, Bart G., Egan, Sharon A., Field, Terence R., Maskell, Duncan, Kehoe, Michael, Dowson, Christopher G. and Chanter, Neil (2009) BMC Genomics, Vol.10 . Article No. 54. doi: ISSN 1471-2164.
Vanlaere, Elke, Baldwin, Adam, Gevers, Dirk, Henry, Deborah, De Brandt, Evie, LiPuma, John J., Mahenthiralingam, Eshwar, Speert, David P., Dowson, Christopher G. and Vandamme, Peter (2009) International Journal of Systematic and Evolutionary Microbiology, Vol.59 (Part 1). pp. 102-111. doi: ISSN 1466-5026.
De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim (2008) Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. doi: ISSN 0021-9258.
Marttinen, Pekka, Baldwin, Adam, Hanage, William P., Dowson, Christopher G. and Mahenthiralingam, Eshwar (2008) BMC Bioinformatics, Vol.9 (No.421). doi: ISSN 1471-2105.
Waine, David J., Honeybourne, David, Smith, E. Grace, Whitehouse, Joanna L. and Dowson, Christopher G. (2008) Journal of Clinical Microbiology, Vol.46 (No.10). pp. 3491-3493. doi: ISSN 0095-1137.
Vanlaere, Elke, LiPuma, John J., Baldwin, Adam, Henry, Deborah, De Brandt, Evie, Mahenthiralingam, Eshwar, Speert, David, Dowson, Christopher G. and Vandamme, Peter (2008) International Journal of Systematic and Evolutionary Microbiology, Vol.58 (Part 7). pp. 1580-1590. doi: ISSN 1466-5026.
Mahenthiralingam, Eshwar, Baldwin, A. (Adam) and Dowson, Christopher G. (2008) Journal of Applied Microbiology, Vol.104 (No.6). pp. 1539-1551. ISSN 1364-5072 doi:
Lloyd, Adrian J., Gilbey, Andrea M., Blewett, Anne M., De Pascale, Gianfranco, El Zoeiby, Ahmed, Levesque, Roger C., Catherwood, Anita C., Tomasz, Alexander, Bugg, Tim, Roper, David I. and Dowson, Christopher G. (2008) Journal of Biological Chemistry, Vol.283 (No.10). pp. 6402-6417. doi: ISSN 0021-9258.
Drevinek, Pavel, Baldwin, Adam, Dowson, Christopher G. and Mahenthiralingam, Eshwar (2008) BMC Microbiology, Vol.8 (No.44). doi: ISSN 1471-2180.
Baldwin, Adam, Mahenthiralingam, Eshwar, Drevinek, Pavel, Pope, Chris, Waine, David J., Henry, Deborah A., Speert, David P., Carter, Phil, Vandamme, Peter, LiPuma, John J. and Dowson, Christopher G. (2008) Journal of Clinical Microbiology, Vol.46 (No.1). pp. 290-295. doi: ISSN 0095-1137.
Lysenko, Elena S., Clarke, Thomas B., Shchepetov, Mikhail, Ratner, Adam J., Roper, David I., Dowson, Christopher G. and Weiser, Jeffrey N. (2007) PL o S Pathogens , Vol.3 (No.8). pp. 1073-1081. doi: ISSN 1553-7366.
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2007) Bioorganic & Medicinal Chemistry Letters, Vol.17 (No.16). pp. 4654-4656. doi: ISSN 0960-894X.
Lysenko, Elena S., Clarke, Thomas B., Shchepetov, Mikhail, Ratner, Adam J., Roper, David I., Dowson, Christopher G. and Weiser, Jeffrey N. (2007) PLoS Pathogens, Vol.3 (No.8). pp. 1073-1081. doi: ISSN 1553-7374.
Dalmastri, Claudia, Baldwin, Adam, Tabacchioni, Silvia, Bevivino, Annamaria, Mahenthiralingam, Eshwar, Chiarini, Luigi and Dowson, Christopher G. (2007) Environmental Microbiology, Vol.9 (No.7). pp. 1632-1639. doi: ISSN 1462-2912.
Waine, David J., Henry, Deborah A., Baldwin, Adam, Speert, David P., Honeybourne, David, Mahenthiralingam, Eshwar and Dowson, Christopher G. (2007) Journal of Cystic Fibrosis, Vol.6 (No.3). pp. 215-219. doi: ISSN 1569-1993.
Baldwin, Adam, Mahenthiralingam, Eshwar, Drevinek, Pavel, Vandamme, Peter, Govan, John R., Waine, David J., LiPuma, John J., Chiarini, Luigi, Dalmastri, Claudia, Henry, Deborah A., Speert, David P., Honeybourne, David, Maiden, Martin C. J. and Dowson, Christopher G. (2007) Emerging Infectious Diseases , Vol.13 (No.3). pp. 458-461. doi: ISSN 1080-6059.
Moore, Lisa J., Gilbey, Andrea M., Dowson, Christopher G., Pridmore, Alison C., Dower, Steven K. and Read, Robert C. (2007) Journal of Antimicrobial Chemotherapy, Volume 59 (Number 1). pp. 35-42. doi: ISSN 0305-7453.
Gardner, J. W., Apostolidou, A., Cole, Marina, Dowson, Christopher G., Edmunds, S. and Sehra, G. (2007) In: 5th IASTED International Conference on Biomedical Engineering, Innsbruck, Austria, 14-16 Feb 2007. Published in: Proceedings of the Fifth IASTED International Conference on Biomedical Engineering pp. 277-282. ISBN 9780889866485.
Mahenthiralingam, Eshwar, Baldwin, Adam, Drevinek, Pavel, Vanlaere, Elke, Vandamme, Peter, LiPuma, John J. and Dowson, Christopher G. (2006) PLoS One, Vol.1 (No.1). doi: ISSN 1932-6203.
Schouten, James A., Bagga, Sangeev, Lloyd, Adrian J., De Pascale, Gianfranco, Dowson, Christopher G., Roper, David I. and Bugg, Timothy D. H. (2006) Molecular BioSystems, 2 (10). pp. 484-491. doi: ISSN 1742-206X.
T枚temeyer, Sabine, Sheppard, Mark, Lloyd, Adrian, Roper, David I., Dowson, Christopher G., Underhill, David, Murray, Peter, Maskell, Duncan and Bryant, Clare (2006) Journal of Immunology, Vol.176 (No.8). pp. 4804-4810. ISSN 0022-1767.
Nelson, E. A., O'Meara, S., Craig, D, Iglesias, C., Golder, S, Dalton, J, Claxton, K, Bell-Syer, S.E.M., Jude, E, Dowson, Christopher G., Gadsby, Roger, O'Hare, J. Paul and Powell, John (2006) Health Technology Assessment, Volume 10 (Number 12). 1-+. ISSN 1366-5278
Smith, Edward M., Green, Laura E., Medley, Graham, Bird, H. E. and Dowson, Christopher G. (2005) Journal of Clinical Microbiology, Vol.43 (No.9). pp. 4731-4736. doi: ISSN 0095-1137.
Smith, Edward M., Green, Laura E., Medley, Graham, Bird, H. E., Fox, L. K., Schukken, Y. H., Kruze, J. V. , Bradley, Andrew J., Zadoks, Ruth N. and Dowson, Christopher G. (2005) Journal of Clinical Microbiology, Vol.43 (No.9). pp. 4737-4743. doi: ISSN 0095-1137.
Gardner, J. W., Hines, E.L. and Dowson, Christopher G. (2004) London, UK: Ingenia.
Yates, J. W. T., Gardner, J. W., Chappell, M. J. (Michael J.), Bolt, F., Beeby, L. and Dowson, Christopher G. (2003) In: 5th IFAC Symposium on Modelling and Control in Biomedical Systems, Melbourne, Australia, 21-23 Aug 2003. Published in: Modellling and Control in Biomedical Systems 2003 (including Biology Systems) pp. 289-294. ISBN 0080441599. ISSN 0962-9505.
| Title | Funder | Award start | Award end |
| Adapting Versatile Opportunities for Glycopeptide Antibiotics against Drug-Resistant Organisms (AVOGADRO) - Full Stage Application to AMR Interventions 2024 led by University of Tubingen (Outline 80593) | Medical Research Council (MRC) | 01 April 2025 | 31 March 2028 |
| Multidisciplinary toolbox for characterising lipid II binding antibiotics - Standard Grant | EPSRC | 01 April 2025 | 31 March 2028 |
| MTA Kitasato | The Kitasato Institute | 01 March 2025 | 29 February 2028 |
| Antimicrobial Resistance: Breakthrough Compound Discovery through Mechanistic Studies combined with Bicycle Technology and Target Validation - BBSRC Prosperity Partnership Full Stage - March 2023 | BBSRC | 15 November 2023 | 14 November 2026 |
| Healthcare Associated Infections and Antimicrobial Resistance at Imperial College | National Institute for Health Research (NIHR DoH) | 01 April 2020 | 30 September 2025 |
| MEDICAL RESEARCH FOUNDATION NATIONAL PHD TRAINING PROGRAMME IN ANTIMICROBIAL RESISTANCE RESEARCH - A-code | Medical Research Foundation | 01 October 2017 | 30 September 2025 |
| Enabling public and private partnership platforms to accelerate antibiotic discovery linked to 72691 | Rosalind Franklin Institute | 21 July 2022 | 20 November 2024 |
| Sulbactam cefepime | ANTRUK Enterprises Limited | 02 January 2020 | 31 March 2024 |
| Developing mechanistic understanding to improve the activity of bicyclic peptides as novel antimicrobials | MRC | 13 September 2021 | 12 September 2023 |
| Developing mechanistic understanding to improve the activity of bicyclic peptides as novel antimicrobials linked to 69055 | BicycleTX Ltd | 13 September 2021 | 12 September 2023 |
| BBSRC Mid-range Equipment ALERT 2021 Application - November 2021 | BBSRC | 01 August 2022 | 31 July 2023 |
| MRC UK China Hubs | MRC | 01 January 2019 | 31 March 2022 |
| CoA: CHNUK: Integrated platforms from science to policy in response to antibacterial resistance; linked to Ideate 58956 | UK Research and Innovation | 01 July 2020 | 30 September 2021 |
| CoA: [Mechanistic understanding of cell wall biosynthesis to combat antimicrobial resistance: Cell Wall AMR]; linked to Ideate 46475 | UK Research and Innovation | 01 March 2021 | 28 August 2021 |
| Mechanistic understanding of cell wall biosynthesis to combat antimicrobial resistance: Cell Wall AMR | MRC | 01 July 2015 | 28 August 2021 |
| 19 Alert mid-range Equipment Initiative: equipment to upgrade the 600 NMR console at the NMR facility. | BBSRC | 01 November 2020 | 31 March 2021 |
| Science City TM1 Clinical Trials (糖心TV-led) - Inter Institutional Agreement | Advantage West Midlands | 01 August 2009 | 31 July 2019 |
| Accelerate CHNUK AMR discovery: Establishing and exploiting a joint China/UK platform to enable high throughput fragment based inhibitor discovery | MRC | 01 July 2016 | 30 June 2019 |
| Research Project on Penicillin (WCPRS) | Micropathology Limited | 05 October 2015 | 04 April 2019 |
| Developing the next generation of beta-lactamase inhibitors and monobactum antibiotics - GCRF network grant | Academy of Medical Sciences | 28 January 2018 | 27 January 2019 |
| Cell wall biosynthesis ? a structural and biochemical characterization of penicillin-binding-proteins Lister summer studentship for Anna Schorfield | Lister Institute of Preventive Medicine | 02 July 2018 | 07 September 2018 |
| Multi-Targetting of tRNA synthetases: A paradigm shift in combating AMR | MRC | 01 March 2015 | 30 November 2017 |
| Development of orally active analogs of Teixobactin | Gates Foundation | 08 February 2017 | 31 October 2017 |
| Cell wall biosynthesis in Yersinia pestis ? a structural and biochemical characterization of penicillin-binding-proteins (Lister Summer Studentship for Rachel Evans) | Lister Institute of Preventive Medicine | 10 July 2017 | 01 September 2017 |
| Enabling novel penicillin-binding-protein high throughput screens | Wellcome Trust | 01 July 2016 | 30 June 2017 |
| International exploitation of new reagents and assays for antibiotic discovery | BBSRC | 03 May 2015 | 02 May 2016 |
| FLIP: Enabling exploitation of novel reagents and assays (EnRgy) | BBSRC | 24 February 2014 | 23 February 2016 |
| Development of assays and reagents in the final steps of peptidoglycan. | AstraZeneca Pharmaceuticals LP | 01 October 2013 | 31 December 2015 |
| Team CanUK: Novel antibacterial targets, assays, probes and opportunities in bacterial cell wall biogenesis | MRC | 01 January 2012 | 31 December 2015 |
| BBSRC Link with Astra Zeneca:Reagents and assays to exploit the final steps of peptidoglycan construction | BBSRC | 01 August 2013 | 31 July 2015 |
| Optimisation of anaerobic digestion (process monitoring) | Guy and Wright Limited | 01 February 2010 | 30 June 2015 |
| Support for Chris Dowson Research - Medical & Life Sciences Research Fund | Medical and Life Sciences Research Fund | 01 December 2013 | 31 July 2014 |
| The biochemical characterisation of pivotal enzymes involved in mycobacterial peptidoglycan biosynthesis Birmingham-糖心TV PG grant | MRC | 01 May 2011 | 30 April 2014 |
| Concordance in Diabetic Foot Ulceration - CODIFI (lead: University of Leeds) | National Institute for Health Research (DoH) | 01 April 2011 | 30 September 2013 |
| Unesco- loreal Visiting Fellowship for Vita Majce | UNESCO | 01 May 2012 | 30 April 2013 |
| Inter-Institutional Agreement Science City TM2 Experimental Medicine (Birmingham-led) | Advantage West Midlands | 20 July 2009 | 31 March 2012 |
| Match funding for Chris Dowson Micropathology donation | Higher Education Funding Council for England | 01 February 2010 | 31 January 2011 |
| Funding for Medical Research Fund Arden Fellow - Adam Baldwin | Micropathology Limited | 01 August 2008 | 31 October 2010 |
| Medical Research Fund Arden Fellowship - Support for Elli Pinnock | Micropathology Limited | 01 October 2009 | 17 September 2010 |
| UKCan - BACWAN | MRC | 01 August 2009 | 30 April 2010 |
| UK BACWAN 2 | University of Sheffield | 01 May 2008 | 30 April 2010 |
| CASE STUDENTSHIP - Eleanor Pinnock | Micropathology Limited | 01 October 2006 | 30 September 2009 |
| TIME EXTENSION ONLY - Indistinguishability Analysis for Model Discrimination in Systems Biology: A Feasibility Study Applied to Bacterial Peptidoglycan Biosynthesis | EPSRC | 01 May 2009 | 31 July 2009 |
| Indistinguishability Analysis for Model Discrimination in Systems Biology: A Feasibility Study Applied to Bacterial Peptidoglycan Biosynthesis | EPSRC | 01 April 2007 | 31 March 2009 |
| Indistinguishability Analysis for Model Discrimination in Systems Biology: A Feasibility Study Applied to Bacterial Peptidoglycan Biosynthesis | EPSRC | 01 April 2007 | 31 March 2009 |
| Funding for Medical Research Fund Arden Fellow - Adam Baldwin | Micropathology Limited | 01 November 2008 | 31 January 2009 |
| Purchase of Kinetic Spectrophotometer | Eveson Charitable Trust | 01 February 2008 | 31 January 2009 |
| Comparative Virulence of Clinical, Industrial and Environmental Isolates of the Opportunistic pathogen Pseudomonas Auruginosa - SGM summer studentship | Society for General Microbiology | 21 July 2008 | 12 September 2008 |
| Funding for Medical Research Fund Arden Fellow - Adam Baldwin | Micropathology Limited | 01 May 2008 | 31 July 2008 |
| UK - BaCWAN: UK-Bacterial Cell Wall Assembly Network | MRC | 01 April 2006 | 31 March 2008 |
| Exploration and Exploitation of the Enzymology of PBP Driven Peptidoglycan Biosynthesis to Discover Novel Non-beta Lactam Antibiotics | MRC | 01 March 2005 | 29 February 2008 |
| Expanding global databases for CF pathogens burkholderia cepacia complex and pseudomonas aeruginosa in order to investigate emerging infections. | Cystic Fibrosis Trust | 01 February 2007 | 31 January 2008 |
| MLST Characterisation of Burkholeria cepacia complex orgnaisms | Unilever | 26 October 2007 | 31 December 2007 |
| Screening for 21st Century cell wall inhibitors active against hospital acquired bacterial infections | Medical Research Fund of 糖心TV | 01 June 2007 | 30 November 2007 |
| Molecular Physiology and structural analysis of the innate immune system triggered by bacterial cell wall components | British Pharmacological Society | 01 October 2004 | 30 September 2007 |
| CASE Studentship: Frances Bolt | Micropathology Limited | 01 October 2004 | 30 September 2007 |
| Admin Support - Developing rapid diagnostic tools for the control of infectious disease | WPH Charitable Trust | 01 October 2004 | 30 September 2007 |
| Students into work application - vacation studentship for Duncan Hope | Society for Applied Microbiology | 09 July 2007 | 14 September 2007 |
| Burkholderia Cepacia Complex Isolates from Industrial Origins | Unilever UK Central Resources Limited | 01 October 2006 | 31 January 2007 |
| Multi locus sequence typing, rapid identification, evoluction and gene flux within Burkholderia cepacia complex isolates. | Wellcome Trust | 03 January 2004 | 31 December 2006 |
| Student Research Training Project | South 糖心TVshire General Hospitals NHS Trust | 07 November 2005 | 06 November 2006 |
| Screening for 21st century cell wall inhibitors active against hospital acquired bacterial infections | Medical Research Fund of 糖心TV | 01 January 2006 | 30 September 2006 |
| Purchase of Electronic Noses via MRF | Eveson Charitable Trust | 21 October 2005 | 20 September 2006 |
| Undergraduate Vacation Bursary: Psuedomonas in Mushrooms; Pathogenicity Assessments. | British Society for Plant Pathology | 11 July 2006 | 04 September 2006 |
| Bridging Award for Dr Sehra | Royal Commission for the Exhibition of 1851 | 01 June 2005 | 31 May 2006 |
| Genetic Diversity and Gene Expression in Pseudomonas Aeruginosa - Barry Curran | Micropathology Limited | 01 October 2002 | 30 September 2005 |
| Developing a multilocus sequence typing scheme to characterise the causative agent of acne, Propionibacterium acnes | Society for General Microbiology | 27 June 2005 | 19 August 2005 |
| Contribution to BBSRC case award (Barry Curran)Genetic and Phenotypic Diversity of Pseudomonas Aeruginosa | University Hospitals Coventry and 糖心TVshire NHS Trust | 01 April 2003 | 31 March 2005 |
| The Characterisation and Activities of Compylobacter Jejuni and Listeria Monocylogenes Bacteriophage - CASE Award - James Taylor | Biotek Limited | 02 October 2000 | 30 September 2003 |