Prof Phillip Stansfeld

Phillip Stansfeld

Professor of Chemistry and Life Sciences

Phillip.Stansfeld@warwick.ac.uk
+44 (0)24 765 23864

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About Me

Phillip is Professor in both the School of Life Sciences and the Department of Chemistry

Groups at 糖心TV

Affiliations

School of Life Sciences

Biography

2003 Bsc with Hons (1st Class) Biological Sciences, University of Edinburgh
2007 PhD Biochemistry, University of Leicester
2007-2010 Wellcome Trust Postdoc, University of Oxford
2011-2014 BBSRC Researcher Co-Investigator, University of Oxford
2015-2019 Research Fellow, University of Oxford
2019- Associate Professor (Reader) Computational Biochemistry, University of 糖心TV

Current projects Research interests

One of the fundamental challenges in biological sciences is to visualise biomolecular machines in high-resolution detail. This is notoriously difficult, expensive and time-consuming to achieve by using experimental techniques, especially for proteins that exist in cell membranes, known as Integral membrane proteins (IMPs). These proteins play fundamental roles in cell biology e.g. as processing enzymes, ion channels, drug receptors, and solute transporters.

My group uses computational methods to study IMP structures and currently hosts MemProtMD; a pipeline for inserting experimentally-solved IMP structures into their native bilayer environment and analysing the stability, dynamics and resultant lipid interactions. This resource uses multiscale molecular dynamics (MD) simulations that permit the accurate assembly of an IMP into a membrane at the coarse-grain level, prior to careful assessment of the quality of the IMP structure at atomic resolution.

The MemProtMD pipeline also forms a springboard to studying the dynamics of experimentally solved structures through MD simulations. With the increasing threat of anti-microbial resistance, we are especially interested in bacterial IMPs. Knowledge of the three-dimensional structures of proteins involved in essential processes provides the physical details of potentially viable targets for killing drug-resistant, pathogenic bacteria. By breathing life into these frozen structures we may assess the association of proteins with lipids, drug molecules and other components of the protein complexes.

Publications

Journals

Herdman, M., 'von Ku?gelgen, A., 'Kureisaite-Ciziene, D., 'Duman, R., 'El Omari, K., 'Garman, E. F., 'Kjaer, A., 'Kolokouris, D., 'Lo?we, J., 'Wagner, A., 'Stansfeld, Phillip J., 'Bharat, T., 2022. . Structure, 30 (2), pp. 215-228
'Song, Wanling, 'Corey, Robin, 'Ansell, Tillson, 'Cassidy, C. Keith, 'Horrell, Michael, 'Duncan, Anna, 'Stansfeld, Phillip J., 'Sansom, Mark S. P., 2022. . Journal of Chemical Theory and Computation, 18 (2), pp. 1188-1201
'Ashraf, Khuram U., 'Nygaard, Rie, 'Vickery, Owen N., 'Erramilli, Satchal K., 'Herrera, Carmen M., 'McConville, Thomas H., 'Petrou, Vasileios I., 'Giacometti, Sabrina I., 'Belcher Dufrisne, Meagan, 'Nosol, Kamil, 'Zinkle, Allen P., 'Graham, Chris L. B., 'Loukeris, Michael, 'Kloss, Brian, 'Skorupinska-Tudek, Karolina, 'Swiezewska, Ewa, 'Roper, David I., 'Clarke, Oliver B., 'Uhlemann, Anne-Catrin, 'Kossiakof, Anthony A. et al (Select to open full list), 2022. . Nature, 604, pp. 371-376
'Oluwole, Abraham O., 'Corey, Robin A., 'Brown, Chelsea M., 'Hern?ndez-Rocamora, Victor M., 'Stansfeld, Phillip J., 'Vollmer, Waldemar, 'Bolla, Jani R., 'Robinson, Carol V., 2022. . Nature Communications, 13 (1)
'Maloney, Finn P., 'Kuklewicz, Jeremi, 'Corey, Robin A., 'Bi, Yunchen, 'Ho, Ruoya, 'Mateusiak, Lukasz, 'Pardon, Els, 'Steyaert, Jan, 'Stansfeld, Phillip J., 'Zimmer, Jochen, 2022. . Nature, 604, pp. 195-201
'Caldwell, Tracy A., 'Vickery, Owen N., 'Colburn, Jonathan David, 'Stansfeld, Phillip J., 'Columbus, Linda, 2022. . Biophysical Journal, 121 (11), pp. 2078-2083
'Williams, Sophie I, 'Yu, Xiulian, 'Ni, Tao, 'Gilbert, Robert J C, 'Stansfeld, Phillip J., 2022. . Journal of molecular biology, 434 (13)
'Radhakrishnan, Anjana, 'Brown, Chelsea M., 'Guy, Collette S., 'Cooper, Charlotte, 'Pacheco-G?mez, Ra?l, 'Stansfeld, Phillip J., 'Fullam, Elizabeth, 2022. . RSC Medicinal Chemistry
'Renne, Mike, 'Corey, Robin, 'Ver?ssimo Ferreira, Joana, 'Stansfeld, Phillip J., 'Carvalho, Pedro, 2022. . Journal of Cell Biology, 221 (9)
Burt, Alister, Cassidy, C. Keith, Stansfeld, Phillip J., Gutsche, Irina, 2021. . Biomolecules, 11 (4)
Pipatpolkai, Tanadet, Quetschlich, Daniel, Stansfeld, Phillip J., 2021. . Journal of Molecular Biology
Perkins, Arden, Tudorica, Dan A., Teixeira, Raphael D., Schirmer, Tilman, Zumwalt, Lindsay, Ogba, O. Maduka, Cassidy, C. Keith, Stansfeld, Phillip J., Guillemin, Karen, Cooper, Vaughn S., 2021. . mBio, 12 (3)
Vickery, Owen N., Stansfeld, Phillip J., 2021. . Journal of Chemical Theory and Computation, 17 (10), pp. 6472-6482
Ansell, T. Bertie, Curran, Luke, Horrell, Michael R., Pipatpolkai, Tanadet, Letham, Suzanne C., Song, Wanling, Siebold, Christian, Stansfeld, Phillip J., Sansom, Mark S. P., Corey, Robin A., 2021. . Journal of Chemical Theory and Computation, 17 (10), pp. 6548-6558
Klug, Yoel A., Deme, Justin C., Corey, Robin A., Renne, Mike F., Stansfeld, Phillip J., Lea, Susan M., Caralho, Pedro, 2021. . Nature Communications, 12
Furze, Christopher M., Delso, Ignacio, Casal, Enriqueta, Guy, Collette S., Seddon, Chloe, Brown, Chelsea M., Parker, Hadyn L., Radhakrishnan, Anjana, Pacheco-Gomez, Raul, Stansfeld, Phillip J., Angulo, Jesus, Cameron, Alexander D., Fullam, Elizabeth, 2021. . Journal of Biological Chemistry, 296
Corey, Robin A., Song, Wanling, Duncan, Anna L., Ansell, T. Bertie, Sansom, Mark S. P., Stansfeld, Phillip J., 2021. . Science Advances, 7 (34)
Silberberg, Jakob M., Corey, Robin A., Hielkema, Lisa, Stock, Charlott, Stansfeld, Phillip J., Paulino, Cristina, H盲nelt, Inga, 2021. . Nature Communications, 12 (1)
Moseng, Mitchell A., Lyu, Meinan, Pipatpolkai, Tanadet, Glaza, Przemyslaw, Emerson, Corey C., Stewart, Phoebe L., Stansfeld, Phillip J., Yu, Edward W., 2021. . mBio, 12 (2)
Simcock, Patrick W., Bublitz, Maike, Cipcigan, Flaviu, Ryadnov, Maxim G., Crain, Jason, Stansfeld, Phillip J., Sansom, Mark S. P., 2021. . Journal of Chemical Theory and Computation, 17 (2), pp. 1218-1228
'Quetschlich, Daniel, 'Esser, Tim K., 'Newport, Thomas D., 'Fiorentino, Francesco, 'Shutin, Denis, 'Chen, Siyun, 'Davis, Rachel, 'Lovera, Silvia, 'Liko, Idlir, 'Stansfeld, Phillip J., 'Robinson, Carol V., 'Martelli, Pier Luigi, 2021. . Bioinformatics, 37 (24), pp. 4876-4878
'Dinsdale, Ria L., 'Pipatpolkai, Tanadet, 'Agostinelli, Emilio, 'Russell, Angela J., 'Stansfeld, Phillip J., 'Tammaro, Paolo, 2021. . Proceedings of the National Academy of Sciences of the United States of America, 118 (34)
'Hammond, Katharine, 'Cipcigan, Flaviu, 'Al Nahas, Kareem, 'Losasso, Valeria, 'Lewis, Helen, 'Cama, Jehangir, 'Martelli, Fausto, 'Simcock, Patrick W., 'Fletcher, Marcus, 'Ravi, Jascindra, 'Stansfeld, Phillip J., 'Pagliara, Stefano, 'Hoogenboom, Bart W., 'Keyser, Ulrich F., 'Sansom, Mark S. P., 'Crain, Jason, 'Ryadnov, Maxim G., 2021. . ACS Nano, 15 (6), pp. 9679-9689
Ni, Tao, Jiao, Fang, Yu, Xiulian, Aden, Sa?a, Ginger, Lucy, Williams, Sophie, Bai, Fangfang, Pra?谩k, Vojtech, Karia, Dimple, Stansfeld, Phillip J., Zhang, Peijun, Munson, George, Anderluh, Gregor, Scheuring, Simon, Gilbert, Robert J. C., 2020. . Science Advances, 6 (5)
Burt, Alister, Cassidy, C. Keith, Ames, Peter, Bacia-Verloop, Maria, Baulard, Megghane, Huard, Karine, Luthey-Schulten, Zaida, Desfosses, Ambroise, Stansfeld, Phillip J., Margolin, William, Parkinson, John S., Gutsche, Irina, 2020. . Nature Communications, 11
Bolla, Jani Reddy, Corey, Robin A., Sahin, Cagla, Gault, Joseph, Hummer, Alissa, Hopper, Jonathan T. S., Lane, David P., Drew, David, Allison, Timothy M., Stansfeld, Phillip J., Robinson, Carol V., Landreh, Michael, 2020. . Angewandte Chemie International Edition, 59 (9), pp. 3523-3528
Cassidy, Keith, Himes, Benjamin A., Sun, Dapeng, Ma, Jun, Zhao, Gongpu, Parkinson, John S., Stansfeld, Phillip J., Luthey-Schulten, Z., Zhang, Peijun, 2020. . Communications Biology, 3 (24)
Corey, Robin A., Stansfeld, Phillip J., Sansom, Mark S. P., 2020. . Biochemical Society Transactions, 48 (1), pp. 25-37
von K眉gelgen, Andriko, Tang, Haiping, Hardy, Gail G., Kureisaite-Ciziene, Danguole, Brun, Yves V., Stansfeld, Phillip J., Robinson, Carol V., Bharat, Tanmay A. M., 2020. . Cell, 180 (2), pp. P348-358.E15
Pye, Valerie E., Rosa, Annachiara, Bertelli, Cinzia, Struwe, Weston B., Maslen, Sarah L., Corey, Robin A., Liko, Idlir, Hassall, Mark, Mattiuzzo, Giada, Ballandras-Colas, Allison, Nans, Andrea, Takeuchi, Yasuhiro, Stansfeld, Phillip J., Skehel, J. Mark, Robinson, Carol V., Pizzato, Massimo, Cherepanov, Peter, 2020. . Nature Structural & Molecular Biology, 27, pp. 78-83
Rao, Shanlin, Bates, George T., Matthews, Callum R., Newport, Thomas D., Vickery, Owen N., Stansfeld, Phillip J., 2020. . Structure, 28 (4), pp. 475-487
Yamamoto, Eiji, Domanski,, Jan, Naughton, Fiona B., Best , Robert B., Kalli, Antreas C., Stansfeld, Phillip J., Sansom, Mark S. P., 2020. . Science Advances, 6 (8)
Domanski, Jan, Sansom, Mark S. P., Stansfeld, Phillip J., Best, Robert B., 2020. . PLOS Computational Biology, 16 (6)
Dijkman, Patricia M., Mu帽oz-Garc铆a, Juan C., Steven R., Lavington, Suemy Kumagai, Patricia, dos Reis, Rosana I., Yin, Daniel, Stansfeld, Phillip J., Costa-Filho, Antonio Jos茅, Watt , Anthony, 2020. . Science Advances, 6 (33)
Pipatpolkai, Tanadet, Usher, Samuel, Stansfeld, Phillip J., Ashcroft, Frances M., 2020. . Nature Reviews Endocrinology, 16 (7), pp. 378-393
Cook, Jonathan P., Baverstock, Tyler, McAndrew, Martin B. L., Stansfeld, Phillip J., Roper, David I., Crow, Allister, 2020. . Proceedings of the National Academy of Sciences of the United States of America, 117 (45), pp. 28355-28365
Baker, Alexander, Richards, Sarah-Jane, Guy, Collette S., Congdon, Thomas R., Hasan, Muhammad, Zwetsloot, Alexander J., Gallo, Angelo, Lewandowski, J贸zef R., Stansfeld, Phillip J., Straube, Anne, Walker, Marc, Chessa, Simona, Pergolizzi, Giulia, Dedola, Simone, Field, Robert A., Gibson, Matthew I., 2020. . ACS Central Science, 6 (11), pp. 2046-2052
Palmer, Tracy, Stansfeld, Phillip J., 2020. . Molecular Microbiology, 113 (5), pp. 861-871
Fiorentino, Francesco, Sauer, Joshua B., Qiu, XingYu, Corey, Robin A., Cassidy, Keith, Mynors-Wallis, Benjamin, Mehmood, Shahid, Bolla, Jani R., Stansfeld, Phillip J., Robinson, Carol V., 2020. . Nature Chemical Biology, 17, pp. 187-195
Stansfeld, Phillip J., 2020. . Biophysical Journal, 119 (8), pp. 1467-1469
Deme, Justin C., Johnson, Steven, Vickery, Owen N., Muellbauer, Amy, Monkhouse, Holly, Griffiths, Thomas, Hennell James, Rory, Berks, Ben C., Coulton, James W., Stansfeld, Phillip J., Lea, Susan M., 2020. . Nature microbiology, 5, pp. 1553-1564
Tohidifar, Payman, Bodhankar,, Girija, Pei, Sichong, Cassidy, C. Keith, Walukiewicz, Hanna, Orodal, George, Stansfeld, Phillip J., Rao, Christopher, 2020. . mBio, 11
Pipatpolkai, Tanadet, Corey, Robin A., Proks, Peter, Ashcroft, Frances M., Stansfeld, Phillip J., 2020. . Communications chemistry, 3
Tasc贸n, Igor, Sousa, Joana S., Corey, Robin A., Mills, Deryck J., Griwatz, David, Aum眉ller, Nadine, Mikusevic, Vedrana, Stansfeld, Phillip J., Vonck, Janet, H盲nelt, Inga, 2020. . Nature Communications, 11 (1)
Rao, Shanlin, Klesse, Gianni, Stansfeld, Phillip J., Tucker, Stephen J., Sansom, Mark S. P., 2019. . Proceedings of the National Academy of Sciences of the United States of America, 116 (28), pp. 13989-13995
Rinn茅, Susanne, Kiper, Aytug K., Vowinkel, Kirsty S., Ram铆rez, David, Schewe, Marcus, Bedoya, Mauricio, Aser, Diana, Gensler, Isabella, Netter, Michael F., Stansfeld, Phillip J., Baukrowitz, Thomas, Gonzalez, Wendy, Decher, Niels, 2019. . eLife, 8
Caffalette, Christopher A., Corey, Robin A., Sansom, Mark S. P., Stansfeld, Phillip J., Zimmer, Jochen, 2019. . Nature Communications, 10 (1)
Abraham, Mark, Apostolov, Rossen, Barnoud, Jonathan, Bauer, Paul, Blau, Christian, Bonvin, Alexandre M.J.J., Chavent, Matthieu, Chodera, John, Condic-Jurkic, Karmen, Delemotte, Lucie, Grubm眉ller, Helmut, Howard, Rebecca J., Jordan, E. Joseph, Lindahl, Erik, Ollila, O. H. Samuli, Selent, Jana, Smith, Daniel G. A., Stansfeld, Phillip J., Tiemann, Johanna K.S., Trellet, Mikael et al (Select to open full list), 2019. . Journal of Chemical Information and Modeling, 59 (10), pp. 4093-4099
Bushell, Simon R., Pike, Ashley C. W., Falzone, Maria E., Rorsman, Nils J. G., Ta, Chau M., Corey, Robin A., Newport, Thomas D., Christianson, John C., Scofano, Lara F., Shintre, Chitra A., Tessitore, Annamaria, Chu, Amy, Wang, Qinrui, Shrestha, Leela, Mukhopadhyay, Shubhashish M. M., Love, James D., Burgess-Brown, Nicola A., Sitsapesan, Rebecca, Stansfeld, Phillip J., Huiskonen, Juha T. et al (Select to open full list), 2019. . Nature Communications, 10 (1)
Corey, Robin A., Vickery, Owen N., Sansom, Mark S. P., Stansfeld, Phillip J., 2019. . Journal of Chemical Theory and Computation, 15 (10), pp. 5727-5736
Parker, Joanne L., Corey, Robin A., Stansfeld, Phillip J., Newstead, Simon, 2019. . Nature Communications, 10
Autzen, Henriette E., Kolds酶, Heidi, Stansfeld, Phillip J., Gourdon, Pontus, Sansom, Mark S. P., Nissen, Poul, 2018. . Biochemistry, 57 (28), pp. 4063-4073
Chavent, Matthieu, Karia, Dimple, Kalli, Antreas C., Domanski, Jan, Duncan, Anna L., Hedger, George, Stansfeld, Phillip J., Seiradake, Elena, Jones, E. Yvonne, Sansom, Mark S. P., 2018. . Structure, 26 (7), pp. 1025-1034.e2
Liko, Idlir, Degiacomi, Matteo T., Lee, Sejeong, Newport, Thomas D., Gault, Joseph, Reading, Eamonn, Hopper, Jonathan T. S., Housden, Nicholas G., White, Paul, Colledge, Matthew, Sula, Altin, Wallace, B. A., Kleanthous, Colin, Stansfeld, Phillip J., Bayley, Hagan, Benesch, Justin L. P., Allison, Timothy M., Robinson, Carol V., 2018. . Proceedings of the National Academy of Sciences of the United States of America, 115 (26), pp. 6691-6696
Rao, Shanlin, Lynch, Charlotte I., Klesse, Gianni, Oakley, Georgia E., Stansfeld, Phillip J., Tucker, Stephen J., Sansom, Mark S. P., 2018. . Faraday Discussions, 209, pp. 231-247
Domanski, Jan, Sansom, Mark S. P., Stansfeld, Phillip J., Best, Robert B., 2018. . Journal of Chemical Theory and Computation, 14 (3), pp. 1706-1715
Newport, Thomas D., Sansom, Mark S. P., Stansfeld, Phillip J., 2018. . Nucleic Acids Research, 47 (D1), pp. D390-D397
Ni, Tao, Williams, Sophie I., Rezelj, Sa?a, Anderluh, Gregor, Harlos, Karl, Stansfeld, Phillip J., Gilbert, Robert J. C., 2018. . Science Advances, 4 (3)
El Ghachi, Meriem, Howe, Nicole, Huang, Chia-Ying, Olieric, Vincent, Warshamanage, Rangana, Touz茅, Thierry, Weichert, Dietmar, Stansfeld, Phillip J., Wang, Meitian, Kerff, Fred, Caffrey, Martin, 2018. . Nature Communications, 9 (1)
Stansfeld, Phillip J., 2017. . Current Opinion in Structural Biology, 45, pp. 133-141
Tolia, Niraj H, Cutts, Erin E., Laasch, Niklas, Reiter, Dirk M., Trenker, Raphael, Slater, Leanne M., Stansfeld, Phillip J., Vakonakis, Ioannis, 2017. . PLoS Pathogens, 13 (8)
Rao, Shanlin, Klesse, Gianni, Stansfeld, Phillip J., Tucker, Stephen J., Sansom, Mark S. P., 2017. . Channels, 11 (4), pp. 347-353
Domanski, Jan, Hedger, George, Best, Robert B., Stansfeld, Phillip J., Sansom, Mark S. P., 2017. . The Journal of Physical Chemistry B, 121 (15), pp. 3364-3375
Habersetzer, Johann, Moore, Kristoffer, Cherry, Jon, Buchanan, Grant, Stansfeld, Phillip J., Palmer, Tracy, 2017. . Open Biology, 7 (8)
Wiktor, Maciej, Weichert, Dietmar, Howe, Nicole, Huang, Chia-Ying, Olieric, Vincent, Boland, Coil铆n, Bailey, Jonathan, Vogeley, Lutz, Stansfeld, Phillip J., Buddelmeijer, Nienke, Wang, Meitian, Caffrey, Martin, 2017. . Nature Communications, 8 (1)
Gupta, Kallol, Donlan, Joseph A. C., Hopper, Jonathan T. S., Uzdavinys, Povilas, Landreh, Michael, Struwe, Weston B., Drew, David, Baldwin, Andrew J., Stansfeld, Phillip J., Robinson, Carol V., 2017. . Nature, 541 (7637), pp. 421-424
Alcock, Felicity, Stansfeld, Phillip J., Basit, Hajra, Habersetzer, Johann, Baker, Matthew A. B., Palmer, Tracy, Wallace, Mark I., Berks, Ben C., 2016. . eLife, 5
L枚rinczi, Eva, Helliwell, Matthew, Finch, Alina, Stansfeld, Phillip J., Davies, Noel W., Mahaut-Smith, Martyn, Muskett, Frederick W., Mitcheson, John S., 2016. . Journal of Biological Chemistry, 291 (34), pp. 17907-17918
Bolivar, Juan H., Mu帽oz-Garc铆a, Juan C., Castro-Dopico, Tomas, Dijkman, Patricia M., Stansfeld, Phillip J., Watts, Anthony, 2016. . Biochimica et Biophysica Acta (BBA) - Biomembranes, 1858 (6), pp. 1278-1287
Vogeley, L., El Arnaout, T., Bailey, J., Stansfeld, Phillip J., Boland, C., Caffrey, M., 2016. . Science, 351 (6275), pp. 876-880
Gu, Yinghong, Li, Huanyu, Dong, Haohao, Zeng, Yi, Zhang, Zhengyu, Paterson, Neil G., Stansfeld, Phillip J., Wang, Zhongshan, Zhang, Yizheng, Wang, Wenjian, Dong, Changjiang, 2016. . Nature, 531 (7592), pp. 64-69
Paci, Emanuele, Sharma, Satyan, Kim, Brian N., Stansfeld, Phillip J., Sansom, Mark S. P., Lindau, Manfred, 2015. . PLoS One, 10 (12)
Wojdyla, Justyna A., Cutts, Erin, Kaminska, Renata, Papadakos, Grigorios, Hopper, Jonathan T. S., Stansfeld, Phillip J., Staunton, David, Robinson, Carol V., Kleanthous, Colin, 2015. . Journal of Biological Chemistry, 290 (44), pp. 26675-26687
Cutts, E. E., Inglis, A., Stansfeld, Phillip J., Vakonakis, I., Hatzopoulos, G. N., 2015. . Biochemical Society Transactions, 43 (5), pp. 838-843
Cl茅on, Fran莽ois, Habersetzer, Johann, Alcock, Felicity, Kneuper, Holger, Stansfeld, Phillip J., Basit, Hajra, Wallace, Mark I., Berks, Ben C., Palmer, Tracy, 2015. . Molecular Microbiology, 98 (1), pp. 111-129
Stansfeld, Phillip J., Goose, Joseph E., Caffrey, Martin, Carpenter, Elisabeth P., Parker, Joanne L., Newstead, Simon, Sansom, Mark S. P., 2015. . Structure, 23 (7), pp. 1350-1361
Gu, Yinghong, Stansfeld, Phillip J., Zeng, Yi, Dong, Haohao, Wang, Wenjian, Dong, Changjiang, 2015. . Structure, 23 (3), pp. 496-504
Li, Dianfan, Stansfeld, Phillip J., Sansom, Mark S. P., Keogh, Aaron, Vogeley, Lutz, Howe, Nicole, Lyons, Joseph A., Aragao, David, Fromme, Petra, Fromme, Raimund, Basu, Shibom, Grotjohann, Ingo, Kupitz, Christopher, Rendek, Kimberley, Weierstall, Uwe, Zatsepin, Nadia A., Cherezov, Vadim, Liu, Wei, Bandaru, Sateesh, English, Niall J. et al (Select to open full list), 2015. . Nature Communications, 6 (1)
Berks, Ben C., Lea, Susan M., Stansfeld, Phillip J., 2014. . Current Opinion in Structural Biology, 27, pp. 32-37
Chavent, Matthieu, Chetwynd, Alan P., Stansfeld, Phillip J., Sansom, Mark S. P., 2014. . Biochemistry, 53 (42), pp. 6641-6652
Dong, Haohao, Xiang, Quanju, Gu, Yinghong, Wang, Zhongshan, Paterson, Neil G., Stansfeld, Phillip J., He, Chuan, Zhang, Yizheng, Wang, Wenjian, Dong, Changjiang, 2014. . Nature, 511 (7507), pp. 52-56
Rothwell, Simon W., Stansfeld, Phillip J., Bragg, Laricia, Verkhratsky, Alexej, North, R. Alan, 2013. . Journal of Biological Chemistry, 289 (2), pp. 618-626
Hatzopoulos, Georgios N., Erat, Mich猫le C., Cutts, Erin, Rogala, Kacper B., Slater, Leanne M., Stansfeld, Phillip J., Vakonakis, Ioannis, 2013. . Structure, 21 (11), pp. 2069-2077
Marzian, Stefanie, Stansfeld, Phillip J., Rapedius, Markus, Rinn茅, Susanne, Nematian-Ardestani, Ehsan, Abbruzzese, Jennifer L., Steinmeyer, Klaus, Sansom, Mark S. P., Sanguinetti, Michael C., Baukrowitz, Thomas, Decher, Niels, 2013. . Nature Chemical Biology, 9 (8), pp. 507-513
Shintre, C. A., Pike, A. C. W., Li, Q., Kim, J-I., Barr, A. J., Goubin, S., Shrestha, L., Yang, J., Berridge, G., Ross, J., Stansfeld, Phillip J., Sansom, M. S. P., Edwards, A. M., Bountra, C., Marsden, B. D., von Delft, F., Bullock, A. N., Gileadi, O., Burgess-Brown, N. A., Carpenter, E. P., 2013. . Proceedings of the National Academy of Sciences of the United States of America, 110 (24), pp. 9710-9715
Stansfeld, Phillip J., Jefferys, Elizabeth E., Sansom, Mark S. P., 2013. . Structure, 21 (5), pp. 810-819
Quigley, A., Dong, Y. Y., Pike, A. C. W., Dong, L., Shrestha, L., Berridge, G., Stansfeld, Phillip J., Sansom, M. S. P., Edwards, A. M., Bountra, C., von Delft, F., Bullock, A. N., Burgess-Brown, N. A., Carpenter, E. P., 2013. . Science, 339 (6127), pp. 1604-1607
Schmidt, Matthias R., Stansfeld, Phillip J., Tucker, Stephen J., Sansom, Mark S. P., 2013. . Biochemistry, 52 (2), pp. 279-281
Rollauer, Sarah E., Tarry, Michael J., Graham, James E., J盲盲skel盲inen, Mari, J盲ger, Franziska, Johnson, Steven, Krehenbrink, Martin, Liu, Sai-Man, Lukey, Michael J., Marcoux, Julien, McDowell, Melanie A., Rodriguez, Fernanda, Roversi, Pietro, Stansfeld, Phillip J., Robinson, Carol V., Sansom, Mark S. P., Palmer, Tracy, H枚gbom, Martin, Berks, Ben C., Lea, Susan M., 2012. . Nature, 492 (7428), pp. 210-214
Rapedius, Markus, Schmidt, Matthias R., Sharma, Chetan, Stansfeld, Phillip J., Sansom, Mark S. P., Baukrowitz, Thomas, Tucker, Stephen J., 2012. . Channels, 6 (6), pp. 473-478
Wemh枚ner, Konstantin, Silbernagel, Nicole, Marzian, Stefanie, Netter, Michael F., Rinn茅, Susanne, Stansfeld, Phillip J., Decher, Niels, 2012. . Journal of Biological Chemistry, 287 (48), pp. 40150-40160
Andres-Enguix, Isabelle, Shang, Lijun, Stansfeld, Phillip J., Morahan, Julia M., Sansom, Mark S. P., Lafreni猫re, Ronald G., Roy, Bishakha, Griffiths, Lyn R., Rouleau, Guy A., Ebers, George C., Cader, Zameel M., Tucker, Stephen J., 2012. . Scientific Reports, 2 (1)
Stansfeld, Phillip J., Sansom, Mark S.P., 2011. . Structure, 19 (11), pp. 1562-1572
Lumb, Craig N., He, Ju, Xue, Yi, Stansfeld, Phillip J., Stahelin, Robert V., Kutateladze, Tatiana G., Sansom, Mark S.P., 2011. . Structure, 19 (9), pp. 1338-1346
Piechotta, Paula L., Rapedius, Markus, Stansfeld, Phillip J., Bollepalli, Murali K., Erhlich, Gunter, Andres-Enguix, Isabelle, Fritzenschaft, Hariolf, Decher, Niels, Sansom, Mark S. P., Tucker, Stephen J., Baukrowitz, Thomas, 2011. . The EMBO Journal, 30 (17), pp. 3607-3619
M盲nnikk枚, Roope, Stansfeld, Phillip J., Ashcroft, Alexandra S., Hattersley, Andrew T., Sansom, Mark S. P., Ellard, Sian, Ashcroft, Frances M., 2011. . The Journal of Physiology, 589 (13), pp. 3071-3083
Streit, Anne K., Netter, Michael F., Kempf, Franca, Walecki, Magdalena, Rinn茅, Susanne, Bollepalli, Murali K., Preisig-M眉ller, Regina, Renigunta, Vijay, Daut, J眉rgen, Baukrowitz, Thomas, Sansom, Mark S. P., Stansfeld, Phillip J., Decher, Niels, 2011. . Journal of Biological Chemistry, 286 (16), pp. 13977-13984
Stansfeld, Phillip J., Sansom, Mark S. P., 2011. . Journal of Chemical Theory and Computation, 7 (4), pp. 1157-1166
Muskett, Frederick W., Thouta, Samrat, Thomson, Steven J., Bowen, Alexander, Stansfeld, Phillip J., Mitcheson, John S., 2010. . Journal of Biological Chemistry, 286 (8), pp. 6184-6191
Domanski, Jan, Stansfeld, Phillip J., Sansom, Mark S. P., Beckstein, Oliver, 2010. . Journal of Membrane Biology, 236 (3), pp. 255-258
Stansfeld, Phillip J., Hopkinson, Richard, Ashcroft, Frances M., Sansom, Mark S. P., 2009. . Biochemistry, 48 (46), pp. 10926-10933
Rouse, Sarah L., Carpenter, Timothy, Stansfeld, Phillip J., Sansom, Mark S. P., 2009. . Biochemistry, 48 (42), pp. 9949-9951
Tai, Kaihsu, Stansfeld, Phillip J., Sansom, Mark S. P., 2009. . Biochemistry, 48 (36), pp. 8758-8763
Ashmole, I., Vavoulis, D. V., Stansfeld, Phillip J., Mehta, Puja R., Feng, J. F., Sutcliffe, M. J., Stanfield, P. R., 2009. . The Journal of Physiology, 587 (20), pp. 4769-4783
Stansfeld, Phillip J., Grottesi, Alessandro, Sands, Zara A., Sansom, Mark S. P., Gedeck, Peter, Gosling, Martin, Cox, Brian, Stanfield, Peter R., Mitcheson, John S., Sutcliffe, Michael J., 2008. . Biochemistry, 47 (28), pp. 7414-7422
Hardman, Rachael M., Stansfeld, Phillip J., Dalibalta, Sarah, Sutcliffe, Michael J., Mitcheson, John S., 2007. . Journal of Biological Chemistry, 282 (44), pp. 31972-31981
Yuill, K. H., Stansfeld, Phillip J., Ashmole, I., Sutcliffe, M. J., Stanfield, P. R., 2007. . Pfl眉gers Archiv - European Journal of Physiology, 455 (2), pp. 333-348
Stansfeld, Phillip J., Gedeck, Peter, Gosling, Martin, Cox, Brian, Mitcheson, John S., Sutcliffe, Michael J., 2007. . Proteins: Structure, Function, and Bioinformatics, 68 (2), pp. 568-580
Stansfeld, Phillip J., Sutcliffe, Michael J., Mitcheson, John S., 2006. . Expert Opinion on Drug Metabolism & Toxicology, 2 (1), pp. 81-94
Perry, Matthew, Stansfeld, Phillip J., Leaney, Joanne, Wood, Claire, de Groot, Marcel J., Leishman, Derek, Sutcliffe, Michael J., Mitcheson, John S., 2005. . Molecular Pharmacology, 69 (2), pp. 509-519
Chen, Philip E., Geballe, Matthew T., Stansfeld, Phillip J., Johnston, Alexander R., Yuan, Hongjie, Jacob, Amanda L., Snyder, James P., Traynelis, Stephen F., Wyllie, David J. A., 2005. . Molecular Pharmacology, 67 (5), pp. 1470-1484

Teaching and supervision

Phillip is the module lead for and teaches on the CH3F1 undergraduate Chemistry module

He also teaches on BS244 and BS348 in Life Sciences, and postgraduate PX923 and MIBTP masterclasses.

I am supervising the following PhD students:

Martin McAndrew (MRC DTP)
Chelsea Brown (MRC DTP)
Becca Bailey (MRC DTP)
Matyas Parrag (HetSys)
Patrick Simcock (Oxford/IBM)
Gaby Dominguez (MBio)
Ron Cvek (MChem)

Please get in touch if you would like to join the team.