Dr Lona Alkhalaf

Assistant Professor

l.alkhalaf.1@warwick.ac.uk
+44 (0)2476 1 51441
Challis/ Alkhalaf GroupLink opens in a new window

About Me

Biography

Dr Lona Alkhalaf obtained an MChem in Medicinal Chemistry and Pharmacology from the University of Liverpool and a PhD in Chemical Biology from the University of 糖心TV under the supervision of Professor Greg Challis, where she worked on bacterial enzymes involved in making a natural pesticide. She then moved to Vancouver to work at the University of British Columbia in the group of Prof Kaity Ryan on how an antibiotic produced by a bacterium works to treat the infection. She now works at the University of 糖心TV on understanding how all kinds of chemicals are made by bacteria, including those with antibiotic, anticancer and antiviral activity.

Groups at 糖心TV

Challis/Alkhalaf GroupLink opens in a new window

Affiliations

Midlands Integrative Biosciences Training Partnership (BBSRC DTP)

Publications

Selected Publications

C. Huang, D. Zabala, E.L.C. de los Santos, L. Song, C. Corre, L.M. Alkhalaf and G.L. Challis Nucleic Acids Res. 2023, 51, 1488鈥�1499
R Saroay, G-D Roiban, LM Alkhalaf* and G.L. Challis* ChemBioChem, 2021, 22, 2262-2265
S. Zhou, H. Bhukya, N. Malet, P.J. Harrison, D. Rea, M.J. Belousoff, V. Hariprasad, P.K. Sydor, K.M. Styles, L. Song, M.J. Cryle, L.M. Alkhalaf, V. F眉l枚p, G.L. Challis, C. Corre Nature 2021, 590, 463-467
S. Louka, S.M. Barry, D. Heyes, Q.E. Mubarak, H.S. Ali, L.M. Alkhalaf, A.W. Munro, N..S Scrutton, G.L. Challis and S.P. de Visser . J. Am. Chem. Soc. 2020 142, 15764-15779
L.M. Alkhalaf, S.M. Barry, D. Rea, A. Gallo, D. Griffiths, J.R. Lewandowski, V. Fulop and GL. Challis. J. Am. Chem. Soc. 2019 141, 216-222
C .Perry, E.L.C. de los Santos, L.M. Alkhalaf *, G.L. Challis* Nat. Prod. Rep. 2018, 35, 622-632
J.L. Ronan, N. Kadi, S.A. McMahon, J.H. Naismith, L.M. Alkhalaf, G.L. Challis Phil. Trans. Royal Soc. B, 2017, 373, 20170068.
L.M. Alkhalaf, K.S. Ryan Chem. Biol, 2016, 22, 317-328
Y-L. Du, R. Singh, L.M. Alkhalaf, E. Kuatsjah, H-Y. He, L.D. Eltis, K.S. Ryan Nat. Chem. Biol. 2016, 12, 194-199
Y-L. Du, L.M. Alkhalaf, K.S. Ryan . Proc. Natl. Acad. Sci. U.S.A, 2015,112, 2717-2722

Teaching and supervision

I teach on the following courses:

-鈥業ntroduction to Organic Chemistry', first year undergraduate module

-鈥楳echanistic and Biological Chemistry鈥�, second year undergraduate module

-'Extended labs (O3)', 3rd year undergraduate lab

I have previously taught

'Advanced Biophysical Chemistry', 4th year undergraduate module

'Selective Organic Synthesis', second year undergraduate module

I co-supervise the following PhD students:

Yu Zhang (with Prof Greg Challis)

Callum Bullock (with Prof Greg Challis)

Mabilly Cox (with Prof Greg Challis)

Affiah Tasnim (with Prof Greg Challis and Dr Nicole Robb)

Adam Hunt (with Prof Greg Challis and Prof Chris Corre)

Matt Pledge (with Prof Greg Challis, Prof Jian Li and Dr Xinyun Jian)

Emma Coker (with Prof Greg Challis and Prof Jozef Lewandowski)

Duong Nguyen (with Prof Greg Challis)

Xiaoqi Ji (with Prof Greg Challis and Dr Alex Mullins)

Jingyu Zhang (with Prof Greg Challis and Dr Alex Mullins)

Sarah Sonnenberg (with Prof Greg Challis)

I co-supervise the following MChem/MBio final year project students:

Virginia Fisher (with Prof Greg Challis)

Izzy Cannard (with Prof Greg Challis)

If you would like to discuss PhD and Postdoctoral research opportunities please contact me (l.alkhalaf.1@warwick.ac.uk)