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Selected publications

1. Z. Li, R. Qi, Y. Yuan, L. Yang, L. Song, A. Menon, L. Piper, D. Wermeille, P. Thomson, R. House, P. Bruce, A. Robertson, Cation-Disordered Rocksalt Cathode for Anode-Free Zinc-Ion Batteries, Energy and Environmental Science,2025, 18, 10135,
2. W. Scott, E. Molla, D. Akhuli, T. Massam-Wu, P. Lysyganicz, R. Walsh, J. Cook, L. Song, A. Kumar, F. Schneider, M. Mishima, A. Crow, M. Balasubramanian, StayRose: a photostable StayGold derivative red-shifted by genetic code expansion, J. Biol. Chem.,2025, 301 (12), 110832, DOI.org/10.1016/j.jbc.2025.110832
3. C. Corre, G. Idowu, L. Song, M. Whitehead, L. Alkhalaf, G. Challis, Discovery of late intermediates in methylenomycin biosynthesis active against drug-resistant Gram-positive bacterial pathogens, J. Am. Chem. Soc.2025, 147, 40554-40561, DOI: 10.1021/jacs.5c12501
4. A. Bayless, L. Song, M. Sorbello, S. Ogden, T. Todd, A. Flint, N. Maruta, J. Tulu, M. Drenichev, V. Ntoukakis, T. Ye, M. Mobil, L. Wan, Q. Liu, J. Dangl, B. Kobe, M. Grant, M. Nishimura, The Arabidopsis TIRome informs the design of artificial TIR (Toll/interleukin-1 receptor) domain proteins, Proc. Natl. Acad. Sci. U.S.A.2025, 122, 37, e2505893122, doi.org/10.1073/pnas.2505893122
5. C. Borsetto, C. Dykes, B. Kockiri, L. Song, E. Wellington, S. Abolfathi, Constructed wetlands as nature-based barriers: mitigating antimicrobial resistance and pathogen dispersal in riverine systems, J. Hazardous Materials,2025, 495, 138855
6. J. Weaver, D. Alkhder, P. Prasongpholchai, M. Tadesse, E. De Los Santos, L. Song, C. Corre, F. Alberti, Early steps of the biosynthesis of the anticancer antibiotic pleurotin, ACS Chem Biol,2024, DOI: 10.1021/acschembio.4c00599
7. P. Prasongpholchai, S. Tucker, C. Burgess, R. Jenkins, I. Wilkening, C. Corre, L. Song, M. Tosin, Extended polyene formation by a cryptic iterative polyketide synthase from Rjdococcus, Chem Comm.,2024, DOI:10.1039/D4CC04963B
8. Y. Quan, D. Ji, Y. Yuan, H. Xue, R. Qi, S. Coutinho, S. Riedel, Z. Zhao, L. Song, A. Robertson, P. Bruce, R. House, Mg-rich disordered rocksalt oxide cathodes for Mg-ion batteries, J. Mater. Chem. A,2024, DOI: 10.1039/d4ta02348j,
9. A. Dettlaff, J. Tully, G. Wood, D. Chauhan, B. Breeze, L. Song, J. Macpherson, A closed bipolar electrochemical cell for the interrogation of BDD single particles: Electrochemical advanced oxidation, Electrochimica Acta,2024, 485, 144035
10. A. Bayless, S. Chen, S. Ogden, X. Xu, J. Sidda, M. Manik, S. Li, B. Kobe, T. Ve, L. Song, M. Grant, L. Wan, M. Nishimura,Plant and prokaryotic TIR domains generate distinct cyclic ADPR NADase products, Science Advances, 2023,9 (11), eade8487,
11. P. Jacob, J. Hige, L. Song, A. Bayless, D. Russ, V. Bonardi, F. El-Kasmi, L. Wünsch, Y. Yang, C. Fitzpatrick, B. McKinney, M. Nishimura, M. Grant and J. Dangl, Broader functions of TIR domains in Arabidopsis immunity, Proc. Natl. Acad. Sci. U.S.A.2023, 120 (1), e2220921120, DOI 10.1073/pnas.2220921120
12. C. Huang, D. Zabala, E. Santos, L. Song, C. Corre, L. Alkhalaf, and G. Challis Parallelized gene cluster editing illuminates mechanisms of epoxyketone proteasome inhibitor biosynthesis, Nucleic Acids Research, 2023, DOI.org/10.1093/nar/gkad009
13. M. Manik, Y. Shi, S. Li, M. Zaydman, N. Damaraju, V. Masic, T. Mosaiab, S. Hancock, E. Vasquez, L. Hartley-Tassell, N. Maruta, B. Lim, W. Gu, H. Burdett, M. Lansdberg, M. Schembri, N. Kargios, I. Prokes, L. Song, M. Grant, A. DiAntonio, J. Nanson, J. Milbrandt, T. Ve and B. Kobe Chemical structures of cyclic ADP ribose (cADPR) isomers and the molecular basis of their production and signalling, Science, 2022, 377 (6614)
14. F. Wang, I. Prokes, L. Song, H. Shi, P. Sadler, Reactions of cisplatin and oxaliplatin with penicillin G: implications for drug inactivation and biological activity, J. Biol Inorg. Chem., 2022,27 (8), 695-704
15. N. Ashraf, S. Zafar, R. Makitrynskyy, A. Bechthold, D. Spiteller, L. Song, M. Anwar, A. Luzhetskyy, A. Khan, K. Akhtar, S. Khaliq, Revealing genome-based biosynthetic potential of streptomyces sp. BR123 isolated from sunflower rhizophere with broad spectrum antimicrobial activity, Antibiotics,2022,11, 1057 (Doi:10.3390/antibiotics11081057)
16. F. Chen, I. Romero-Canelón, A. Habtemariam, J. Song, S. Banerjee, G. Clarkson, L.Song, I. Prokes and P. Sadler, Effect of cysteine thiols on the catalytic and anticancer activity of Ru (II) sulfonyl-ethylenediamine complexes, Dalton Transactions, 2022, 51 (11), 4447-4457, DOI: 10.1039/D1DT03856G
17. J. Lim, V. Chintalapudi, H. Gudmundsson, M. Tran, A. Bernasconi, A. Blanco, L. Song, G. Challis, E. Anderson, Synthesis of the C1-C27 fragment of stambomycins D validates modular polyketide synthase-based stereochemical assignments, Org. Lett., 2021, 23, 19, 7439-7444, Doi.org/10.1021/acs.orglett.1c02650
18. C. Borsetto, S. Raguideau, E. Travis, D. Kim, D. Lee, A. Bottrill, R. Stark, L. Song, J. Cha, J. Pearson, C. Quince, A. Singer, E. Wellington, Impact of sulfamethoxazole on a riverine microbiome, Water Research, 2021, 117382, 11, doi.org/10.1101/2021.04.01.438070
19. S. Zhou, H. Bhukya, N. Malet, P. Harrison, D. Rea, M. Belousoff, H. Venugopal, P. Sydor, K. Styles, L. Song, M. Cryle, L. Alkhalaf, V. Fulop, G. Challis, C. Corre,, Nature, 2021, 590, 463-467, Doi:10.1038/s41586-021-03195x
20. Chhun, D. Sousoni, M. Aguilo-Ferretjans ,L. Song, C. Corre, J. Christie-Oleza,, Microbio. Biotech, 2020, 14 (1), 291-306, Doi:10.1111/1751-7915.13722
21. J. Sidda, L. Song, J. Parker, D. Studholme, C. Sambles, M. Grant, Diversity of secoiridoid glycosides in leaves of UK and Danish ash provide new insight for ash dieback management, Scientific Rep., 2020, 10(1), 19566, DOI: 10.1038/541598-020-76140-z
22. Zhou, N. Malet,L. Song, C. Corre, G. Challis, MmfL catalyses formation of a phosphorylated butenolide intermediate in methylenomycin furan biosynthesis,Chem Comm., 2020, 56(92), 14443-14446, DOI: 10.1039/D0CC05658H
23. D. Zabala,L. Song, Y. Dashti, G. Challis, J. Salas, C, Mendez. Heterologous reconstitution of the biosynthesis pathway for 4-demethyl-premithramycinone, the aglycone of antitumor polyketide mithramycin,Microbial Cell Factory, 2020, 19 (1), 1-12
24. P. Becher, V. Verschut, M. Bibb, M. Bush, B. Molnar, E. Barane, M. Bassam, G. Chandra, L. Song, G. Challis, M. Buttner, K. Flardh. Developmentally regulated volatiles geosmin and 2-methylisoborneol attract springtails toStreptomycesbacteria as vectors for spore dispersal, Nat. Microbiology, 2020,5, 821-829
25. A. Banks, L. Song, G. Challis, A. Bailey, G. Foster. Bovistol B, bovistol D and strossmayerin: Sesquiterpene metabolites from the culture filtrate of the basidiomyceteCoprinopsis strossmayeri, PLoS ONE, 2020, 15 (4), e0229925
26. S. Zhou, L. Song, J. Masschelein, F. Sumang, I. Papa, T. Zulaybar, A. Custodio, D. Zabala, E. Alcantara, E. de los Santos,G. Challis. Pentamycin Biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-Catalyzed Installation of the C‑14 Hydroxyl Group,ACS Chem. Biol., 2019, 14, 1305-1309
27. 5. D. Thankachan, A. Fazal, D. Francis, L. Song, M. Webb, R. Seipke, A trans-​acting cyclase off-​loading strategy for non-​ribosomal peptide synthetases, ACS Chem Biol., 2019, 14, 845-849
28. F. Alberti, D. Leng, I. Wilkening, M. Tosin, L. Song, C. Corre, Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery, Chem. Sci., 2019,10, 453-463
29. C. Perry, J. Sargeant, L. Song, G. Challis, Relative stereochemical assignment of C33 and C35 in the antibiotic gladiolin, Tetrahedron, 2018,74 (38), 5150-5155
30. S. Banerjee, J. Soldevila, J. Wolny, C. Wootton, A. Habtemariam, I. Romero, F. Chen, G. Clarkson, I. Prokes, L. Song, P. O'Connor, V. Schunemann, P. Sadler. New activation mechanism for half-sandwich organometallic anticancer complexes, Chem Sci., 2018, 9, 3177-3188
31. Z. Anderson, C. Hobson, R. Needley, L. Song, M. Perryman, P. Kerby, and D. Fox, NMR-based assignment of isoleucine vs allo-isoleucine stereochemistry. Organic & Biomolecular Chemistry, 2017, 15, 9372-9378
32. D. Blessborn, K. Kaewkhao, L. Song, NJ White, NPJ Day, J Tarning, Quantification of the antimalarial drug pyronaridine in whole blood using LC-MS/MS-increased sensitivity resulting from reduced non-specific binding, J Pharm Biomed Anal.2017, 146: 214-219
33. L. Song, M. Jenner, J. Masschelein, C. Jones, M. Bull, S. Harris, R. Hartkoorn, A. Vocat, I. Romero-Canelón, P. Coupland, Paul, G. Webster, M. Dunn, R. Weiser, C. Paisey, S. Cole, J. Parkhill, E. Mahenthiralingam and G. L. Challis. Discovery and biosynthesis of gladiolin: a Burkholderia gladioli antibiotic with promising activity against Mycobacterium tuberculosis.J. Am. Chem. Soc. 2017, 139(23)7974-7981
34. O. Tsypik, R. Makitrynskyy, A. Bera, L. Song, W. Wohlleben, V. Fedorenko, B. Ostash, Role of GntR Family Regulatory Gene SCO1678 in Gluconate Metabolism in Streptomyces coelicolor M145, BioMed Research International, 2017, DOI.org/10.1155/2017/9529501
35. Y. Inahashi, S. Zhou, M. Bibb, L. Song, M. Al-Bassam, M. Bibb and G. Challis. Watasemycin biosynthesis in Streptomyces venezuelae: thiazoline C-methylation by a type B radical-SAM methylase homologue. Chem. Sci. 2017, 8, 2823-2831
36. M. Sotenko, S. Coles, G. Barker, L. Song, Y. Jiang, P. Longhurst, T. Romanova, O. Shuvaeva, K. Kirwan. Phytoremediation combined with biorefinery on the example of two agricultural crops grown on Ni soil and degraded by P. chrysosporium. Int. J. Phytoremediation., 2016, Dec 12:0
37. L. Ray, T. Valentic, T. Miyazawa, D. Withall, L. Song, H. Osada, S. Takahashi, S. Tsai, G. Challis, Structural basis for acyl-CoA carboxylase-mediated assembly of unusual polyketide synthase extender units incorporated into the stambomycin antibiotics, Nat Comm., 2016, 7, 13609
38. A. Thanapipatsiri, J. Gomez-Escribano, L. Song, M. Bibb, M. Al-Bassam, G. Chandra, A. Thamchaipenet, G. Challis and M. Bibb, Discovery of unusual biaryl polyketides by activation of a silent Streptomyces venezuelae biosynthetic gene cluster, ChemBioChem, 2016, 17,2189-2198
39. I. Wilkening, S. Gazzola, E. Riva, J. Parascandolo, L. Song, M. Tosin. Second-generation probes for biosynthetic intermediate capture: towards a comprehensive profiling of polyketide assembly. Chem. Commun., 2016, 52, 10392-10395
40. J. Sidda, V. Poon, L. Song, W. Wang, K. Yang, C. Corre. Overproduction and identification of butyrolactones SCB1-8 in the antibiotic production super host Streptomyces M1152. Org. Biomol. Chem., 2016, 14(27), 6390-6393
41. D. Zabala, J. Cartwright, D. Roberts, B. Law, L. Song, M. Samborskyy, P. Leadlay, J. Micklefield, and G. Challis. A flavin-dependent decarboxylase-dehydrogenase-monooxygenase assembles the warhead of α, β-epoxyketone proteasome inhibitors. J. Am. Chem. Soc. 2016, 137, 432-435
42. J. Parascandolo, J. Havemann, H. Potter, F. Huang, E. Riva, J. Connolly, I. Wilkening, L. Song, P. Leadlay, M. Tosin, Novel insights into 6-methylsalicylic acid bio-assembly via chemical probes, Angew. Chem. Int. Ed. 2016,55(10), 3463-3467
43. C. Amaratunga, P. Lim, S. Suon, S. Sreng, S. Mao, C. Sopha, B. Sam, D. Dek, V. Try, R. Amato, D. Blessborn, L. Song, G. Tullo, M. Fay, J. Anderson, J. Tarning, R. Fairhurst. Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multi-site observational cohort study, Lancet Infectious Disease, 2016, 16(3), 357-365
44. N. Liu*, L. Song*, M. Liu*, F. Shang, Z. Anderson, D. Fox, G. L. Challis, Y. Huang, Unique post-translational ­oxime formation in the biosynthesis of the azolemycin complex of novel ribosomal peptides from Streptomyces sp. FXJ1.264, Chem. Sci., 2016,7(1), 482-488 (* Co-first author)
45. B. Uytterhoeven, K. Appermans, L. Song, J. Masschelein, C. Michiels, R. Lavigne, Systematic analysis of the kalimantacin assembly line NRPS module using an adapted targeted mutagenesis approach, Microbiology Open, 2016,5(2), 279-286
46. R. Leang, W. Taylor, D. Bouth, L. Song, J. Tarning, M. Char, S. Kim, B. Witkowski, V. Duru, A. Domergue, N. Khim, P. Ringwald, D. Menard, Evidence of falciparum malaria multidrug resistance to artemisinin and piperaquine in western Cambodia: dihydroartemisinin-piperaquine open-label multicenter clinical assessment. Antimicrob Agents Chemother., 2015,59(8), 4719-4726
47. J. Gubbens, H. Zhu, G. Girard, L. Song, B. Florea,P. Aston, K. Ichinose, D. Filippov, Y. Choi, H. Overkleeft, G. Challis, G. van Wezel, Natural Product Proteomining, a Quantitative Proteomics Platform, Allows Rapid Discovery of Biosynthetic Gene Clusters for Different Classes of Natural Products. Chem. Biol.,2014, 21(6), 707-718
48. L. Song, L. Laureti, C. Corre, P. Leblond, B. Agile, G. L. Challis. Cytochrome P450-mediated hydroxylation is required for polyketide macrolactonisation in stambomycin biosynthesis. J. Antibiotic,2014, 67, 71-76
49. J. Sidda, L. Song, V. Poon, M. Al-Bassam, O. Lazos, M. Buttner, G. Challis, C. Corre. Discovery of a family of γ-aminobutyrate ureas via rational derepression of a silent bacterial gene cluster, Chem. Sci.,2014, 5 (1), 86-89
50. J. Suberu, P. Yamin, K. Leonhard, L. Song, S. Chemat, N. Sullivan, G. Barker, A. Lapkin . The effect of O-methylated flavonoids and other co-metabolites on the crystallization and purification of artemisinin. J. Biotechnol.,2014, 171, 25-33
51. J. Suberu, L. Song, N. Sullivan,S. Slade, G. Barker, A. Lapkin, A rapid method for the determination of artemisinin and its biosynthetic precursor in Artemisia annua L. crude extract. J. Pharm. Biomed. Anal.,2013, 84, 269-277
52. S. Kodani, J. Bicz, L. Song, R. Deeth, M. Ohnish-Kameyama,M. Yoshida, K. Ochi, and G. L. Challis. Structure and biosynthesis of scabichelin, a novel tris-hydroxamate siderophore produced by the plant pathogen Streptomyces scabies 87.22. Org. Biomol. Chem.,2013, 11, 4686-4694
53. Y. Zhao, J Woods, N. Farrer, K. Robinson, J. Pracharova, J. Kasparkova, O. Nokakova, H. Li, L. Salassa, A. Pizarro, G. Clarkson, L. Song, V. Brabec, P. Sadler, Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible light form novel DNA adducts, Chem. Eur. J.,2013, 19(29), 9578-9591
54. J. Gomez-Escribano*, L. Song*, M. Bibb, G.. Challis, Posttranslational β-methylation and macrolactamidination in the biosynthesis of the bottromycin complex of ribosomal peptide antibiotics, Chem. Sci,2012, 3, 3522-3525. (* co-first author)
55. S. Barry, J. Kers, E. Johnson, L. Song, P. Aston, B. Patel, S. Krasnoff, B. Crane, D. Gibson, R. Loria and G. Challis. Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis. Nat. Chem. Biol.,2012, 8, 814-816
56. A. Gerc*, L. Song*, G. L. Challis, N. R. Stanley-Wall, S. J. Coulthurst, Identification and characterisation of the althiomycin biosynthetic operon of Serratia marcescens Db10, PLoS ONE, 2012, 7(9), e44673 (* Co-first Author).
57. J. Gomez-Escribano*, L. Song*, D.J.Fox, M. Bibb, G.L. Challis, Identification of the yellow-pigmented polyketide product of the cryptic cpk gene cluster of Streptomyces coelicolor M145, Chem. Sci,2012,3(9), 2716-2720. (* co-first author)
58. S. Lautru, L. Song, L. Demange, H. Galons, G. L. Challis and Jean-Luc Pernodet. A Sweet Origin for the Key Congocidine Precursor 4-Acetamidopyrrole-2-carboxylate. Angew. Chem Int. Ed.,2012, 51(30), 7454-7458
59. Y. Fu, M. Romero, A. Habtemariam, M. Snowden, L. Song, G. Clarkson, B. Qamar, A. Pizarro, P. Unwin and P. Sadler, The Contrasting Chemical Reactivity of Potent Isoelectronic Iminopyridine and Azopyridine Osmium(II) Arene Anticancer Complexes, Chem. Sci.,2012, 3(8), 2485-2494.
60. P. Milnes, M. McKee, J. Bath, L. Song, E. Stulz, A. Turberfield and R. O'Reilly, Sequence- specific synthesis of macromolecules using DNA-templated chemistry, Chem. Comm.,2012, 48,5614-5616
61. L. Song, L. Laureti, J.-P. Gomez-Escribano, D. Fox, V. Yeo, C. Corre, S. Huang, P. Leblond, B. Aigle, M. Bibb and G. L. Challis. Bacterial Genome Mining for Novel Natural Product Discovery. Planta Med.,2012, 78, 1030
62. S. Schmelz, C.H. Botting, L. Song, N. Kadi, G.L. Challis and J.H. Naismith. Structural basis for acyl acceptor specificity in the achrombactin biosynthetic enzyme AcsD. J. Mol. Biol., 2011, 412 (3)495-504
63. R. Seipke, L. Song, J. Bic, P. Laskaris, A. Yaxley, G. L. Challis, R. Loria, Expression of a pyochelin biosynthetic gene cluster in Streptomyces scabies 87022 is regulated by TetR- and AfsR- family regulatory proteins. Microbiology, 2011, 157, 2681-2693
64. L. Laureti*, L. Song*,S. Huang, C. Corre, P. Leblond, G.L. Challis and B. Aigle. A new class of bioactive macrolide discovered by activation of a silent polyketide synthase. Proc. Nat. Acad. Sci. USA. 2011,108(15), 6258-6263, (*co-first author)
65. E. Mahenthiralingam, L. Song, A. Sass, J. White,C. Wilmot, A. Marchbank, O. Boaisha, J. Paine, D. Knight, G. Challis, Enacyloxins are products of an unusual hybrid modular polyketide synthase encoded by a cryptic Burkholderia ambifaria genomic island. Chem. Biol.,2011, 18(5), 665-677
66. R. Bunet, L. Song, M. V. Mendrea, C. Corre, L. Hotel, N Rouhler, X. Framboisier, P Leblond, G.L.Challis, B. Aigle. Characterisation and manipulation of the pathway specific regulator AlpW reveals Streptomyces ambofaciens a new producer of kinamycins. J. Bacteriol.,2011, 195, 1142-1153
67. P. Sydor, S. Barry, O. Odulate, F. Barona-Gomez, S. Haynes, C. Corre, L. Song, G. L. Challis, Antibiotic Oxidative Carbocyclizations Catalyzed by Rieske Oxygenase-Like Enzymes, Nat. Chem.,2011, 3, 388-392
68. S. Haynes, P. Sydor, C. Corre, L. Song, and G.L. Challis. Stereochemical elucidation of streptorubin B. J. Am. Chem. Soc.,2011, 133 (6), 1793-1798
69. P. Patel, L Song, G.L.Challis, Distinct extracytoplasmic siderophore binding proteins recognise ferrioxamines and ferricoelichelin in Streptomyces Coelicolor A3(2), Biochemistry, 2010, 49, 8033-8042
70. B. Aigle, R. Bunet, C. Corre,; A. Garenaux, L. Hotel, S. Huang, L. Laureti, S. Lautru, M/. Mendes, S. Nezbedova, H. Nguyen, L Song, J. Weiser, G. Challis, P. Leblond, J.Pernodet. Genome-guided exploration of Streptomyces ambofaciens secondary metabolism. Streptomyces,2011, 179-194.
71. Y. Chen, J. Scanlan, L Song, A. Crombie, M. Rahman, H. Schafer, C. Murrell, γ-glutamylmethylamide is essential in the metabolism of methylamine by Methylocella silvestris BL2. Appl. Environ Microbiol., 2010, 76(3), 4530-4537
72. C. Corre, S. W. Haynes, N. Malet, L. Song and G. Challis A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically 13C-labelled glycerols, Chem. Comm.,2010, 46, 4079-4081
73. D. Oves-Costales, L. Song and G. Challis. Enantioselective desymmetrisation of citric acid catalysed by the substrate-tolerant petrobactin biosynthetic enzyme AsbA. Chem. Comm.,2009, 1389-1391.
74. S. Schmelz, N. Kadi, S. McMahon, L. Song, D. Oves-Costales, M. Oke, H. Liu, K. Johnson, L.G. Carter, C.H. Botting, M.F. White, G. Challis and J.H. Naismith, AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis. Nat. Chem. Biol.,2009, 5, 174-182.
75. C. Corre, L. Song, S. O'Rourke, K.F. Chater and G. Challis. 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining. Proc. Nat. Acad. Sci. USA 2008, 105, 17510-17515.
76. N. Kadi, L. Song and G. Challis. Bisucaberin biosynthesis: An adenylating domain of the BibC multi-enzyme catalyzes cyclodimerization of N-hydroxy-N-succinylcadaverine. Chem. Comm.,2008, 5119-5121.
77. Z. Mitchell, M.T.G. Holden, J. Parkhill, L. Song, G. Challis, C. Robinson, N. Davis-Poynter and A.S. Waller. A novel streptococcal integrative conjugative element involved in iron acquisition. Mol. Microbiol.,2008, 70, 1274-1292.
78. D. Oves-Costales, N. Kadi, M.J. Fogg, L. Song, K.S. Wilson and G.L. Challis. Petrobactin biosynthesis: AsbB catalyses ATP-dependent condensation of spermidine with N8-citryl-spermidine and its N1-(3, 4-dihydroxybenzyl) derivative. Chem. Comm.,2008,4034-4036.
79. N. Kadi, S. Arbache, L. Song, D. Oves-Costales and G.L. Challis. Identification of a gene cluster that directs putrebactin biosynthesis in Shewanella species: PubC catalyzes ATP-dependent cyclodimerization of N-hydroxy-N-succinyl-putrescine. J. Am. Chem. Soc., 2008,130, 10458-10459.
80. S. Haynes, P. Sydor, A. Stanley, L. Song and G. Challis. Role and substrate specificity of the Streptomyces coelicolor RedH enzyme in undecylprodiginine biosynthesis. Chem. Comm.,2008, 1865-1867.
81. S. Mo, P. Sydor, C. Corre, M. Alhamadsheh, A. Stanley, S. Haynes, L. Song, K.A. Reynolds and G.L. Challis. Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis. Chem. Biol.,2008, 15, 137-148.
82. D. Oves-Costales, N. Kadi, M. Fogg, L. Song, K. Wilson, G.L. Challis, Enzymatic logic of anthrax stealth siderophore biosynthesis: AsbA catalyzes ATP-dependant condensation of citric acid and spermidine, J. Am. Chem. Soc.,2007, 129, 6017-6018
83. L. Song and P. Thornalley, Effects of storage, cooking and processing on glucosinolates and related metabolites in Brassica vegetables, Food and Chem. Toxicl.,2007, 45, 216-224
84. L. Song, F. Barona-Gomez, C. Corre, L. Xiang, D. W. Udwary, M. Austin, J. P. Noel, B. S. Moore and G. L. Challis, Type III polyketide synthase extender unit specificity in germicidin biosynthesis discovered by Streptomyces Coelicolor genome mining, J. Am. Chem. Soc.,2006, 128, 14754-14755
85. D. Dobler, N. Ahmad, L. Song, K. Eboigbodin, P. Thornalley, Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification, Diabetes, 2006, 55, 1961-1969
86. L. Song, R. Iori, P. Thornalley, Purification of major glucosinolates from Brassicaceae seeds and preparation of isothiocyanates and amine metabolites, J. Sci. Food and Agriculture.2006, 86, 1271-1280
87. L. Song, J. Morrison, N. Botting, P. Thornalley, Analysis of glucosinolates, isothiocyanates and amines degradation products in vegetable extracts and blood plasma by LC-MS/MS, Analytical Biochemistry, 2005, 347, 234-243
88. G. McWalter, L. Higgins, L, McLellan, C. Henderson, L. Song, P. Thornalley, K. Itoh, M. Yamamoto, J. Hayes. Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferase, and glutathione cysteine ligase by broccoli seeds and isothiocyanates, J. Nutrition, 2004, 134, 3499s-3506s