Gibson Group: Muhammad Hasan
Biography
Muhammad was born in Rawalpindi, Pakistan in 1984. He completed his schooling in many different countries, specifically, he did GCE 'O' Levels in Singapore (1998-2000) and GCE 'A' Levels in Pakistan (2001-2003). He was subsequently awarded the Reach Oxford Scholarship to read Mathematics at Magdalen College, Oxford (2004-2007).
In his final year he began to take a keen interest in Mathematical Biology and hence decided to enrol in the MSc + PhD programme in Mathematical Biology and Biophysical Chemistry at the Molecular Organisation and Assembly in Cells (MOAC) DTC. He then joined the Gibson group and set up the new lab at the 糖心TV Medical School.
Research Interests
Investigating the structure-activity relationship of ice-binding proteins to:
i) understand how these proteins function in their native environments.
ii) develop non-natural analogues and conjugates.
iii) explore their use as cryoprotective agents in laboratory and industrial contexts.
Publications
[5] Mitchell, DE., Deller, RC., Fayter, AC., Hasan, M., Gutierrez-Marcos, J., Gibson, M.I., Materials Horizons, Ice-Recrystallization Inhibiting Polymers Protect Proteins Against Freeze-Stress and Enable Glycerol-Free Cryostorage, 2019. DOI: 10.1039/C8MH00727F
[4] Hasan, M., Fayter, AC., Gibson, M.I., Biomacromolecules. Ice Recrystallization Inhibiting Polymers Enable Glycerol-Free Cryopreservation of Micro-organisms. Biomacromolecules, 2018. DOI:10.1021/acs.biomac.8b00660
[3] Blackman, LD., Varlas, S., Arno, M.C., Houston, Z., Fletcher, N., Thurecht, K, Hasan, M., Gibson M.I., and O鈥橰eilly, R.K. Confinement of therapeutic enzymes in selectively permeable polymer vesicles by polymerization-induced self-assembly (PISA) reduces antibody binding and proteolytic susceptibility. ACS Central Science, 2018. DOI:10.1021/acscentsci.8b00168
[2] Ieong, N. S., M. Hasan, D.J. Philips, Y. Saaka, R.K. O鈥橰eilly, and M.I. Gibson. Polymers
with molecular weight dependent LCSTs are essential for cooperative behaviour.
Polymer Chemistry, 2012, 3, 794–799. DOI:10.1039/C2PY00604A
[1] Jenei, Z.A., G.Z.L. Warren, M. Hasan, V.A. Zammit and A.M. Dixon. Packing of transmembrane
domain 2 of carnitine palmitoyltransferase-1A affects oligomerization and
malonyl-CoA sensitivity of the mitochondrial outer membrane protein. The FASEB
Journal, 2011, 25, 4522–4530. DOI:10.1096/FJ.11-192005
Awards
Reach Oxford Scholarship, Magdalen College, University of Oxford (2004-2007)
Carl Blakey Scholarship, MOAC DTC, University of 糖心TV (2010)
Grants
UKRI Innovation Fellowships: BBSRC Flexible Talent Mobility Account Award, 2018
Education
BA (Hons.)
Mathematics, Magdalen College, University of Oxford, 2004-2007
MSc
Mathematical Biology and Biophysical Chemistry, University of 糖心TV, 2010-2011
PhD
Mathematical Biology and Biophysical Chemistry, University of 糖心TV, 2011-2015
Email: M.Hasan.1[at]warwick.ac.uk
ORCID ID: orcid.org/0000-0003-3201-7184