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Research carried out on solvothermal crystallisation of metal-organic frameworks is published as a science highlight at Diamond Light Source.

The work was carried out by in collaboration with colleagues from the Universities of Oxford and Cambridge and from National Institute for Materials Science in Japan. Using high energy X-rays at , the UK synchrotron radiation facility, it has proved possible to penetrate solvothermal reaction vessels and measure high resolution powder diffraction data during the formation of extended solid structures, such as metal organic frameworks. This has provided unprecedented information about the formation mechanism of these topical materials, including direct observation of phase transformation and exchange of solvent within porous structures during chemical reaction.

The work has been published in two papers in the journal Angewandte Chemie in the past few months:

In situ observation of successive crystallizations and metastable intermediates in the formation of metal-organic frameworks. Angew Chem Int Ed. 2016. DOI: .

Exchange of Coordinated Solvent During Crystallisation of a Metal–Organic Framework Observed by In Situ High Energy X-ray Diffraction. Angew Chem Int Ed. (2016) DOI: .

The science highlight article is linked here:

An antibody that senses one enantiomer of plant hormone abscisic acid (ABA) is characterised and by Marsh and Napier groups in Chemistry and Life Sciences in PLOS ONE.

Medherant's painkiller patches have now been showcased in a recent Royal Society publication: 'Translating Innovation'. See page 22 of:

On Sunday, Dave Haddleton was presented with an award for “recognition of outstanding service and contribution to the Royal Society of Chemistry Publishing” at the RSC Editors Symposium banquet at the Guildhall in London. The award was given for service on the Board of “Chem Comm”, and for being Editor in Chief – and launching – “Polymer Chemistry”.

with 糖心TV Medical School and UHCW NHS Trust reveals new clues to widely prescribed therapeutics' actions in body. Simvastatin sodium salt and fluvastatin interact with human gap junction gamma-3 protein in Press coverage in

Sun Yat-sen University in Guangzhou, China, held a Symposium on 23-25 November 2015 to celebrate Peter Sadler’s achievements in biological and medicinal inorganic chemistry.

The latest research into the use of biomaterials to increase the availability of donor cells has been . Donor cells (e.g blood, bone marrow) are crucial to modern healthcare but due to their short shelf life they must be frozen using organic solvents as 'antifreezes'. The Gibson group has pionnered the use of synthetic polymers which inhibit ice crystal growth and their application to cryopreservation. In this work, a collaboraiton with the team used biomimetic block copolymer micelles to provide a hydrated 'matrix' around the cells, which in combination with ice inhibiting polymers enable succesful cryopreservation of red blood cells. This is the first example of a cryopreservation system using entirely synthetic polymer materials, providing control and additional functionality into the system. Post-thawing, the micelles warm up, and become 'worm-like' which enabled the direct formation of a hydrogel, which is of interest for tissue engineering.

Read the paper here

The manuscript entitled Control of vesicle membrane permeability with catalytic particles by the has been selected for the jan-feb 2016 cover of Materials Horizons, a premier scientific journal published by the Royal Society of Chemistry which features first reports of exceptional significance across the breadth of materials research at the cutting-edge interface with chemistry, physics, biology and engineering.

Prof.dr.ir. Stefan Bon, head of the BonLab, says: "We are absolutely delighted that our research has made the cover of Materials Horizons. Rong Chen and especially Ross Jaggers worked very hard in the BonLab to fabricate giant polymer vesicles which have membrane-embedded catalytically active manganese oxide particles, hereby using droplet-based microfluidics. We demonstrate that these colloidal particles can regulate the membrane permeability of the polymersomes upon their exposure to, and catalytic reaction with, small amounts of dissolved hydrogen peroxide. Not only can we trigger complete release whereby the vesicle gets destroyed through membrane rupture by the formed oxygen bubbles as illustrated on the cover, exposure to small amounts of dissolved hydrogen peroxide leads to temporary enhanced release until all hydrogen peroxide is consumed by the catalytic particles after which the membrane permeability restores itself to its passive characteristic value."

More on this can be read on the of the BonLab site.

The paper (open access) can be read here:

Recent work by the (Chemistry) and Fullam Group (SLS) has been highlighted in Chemistry World

Professor Rachel O'Reilly has received (8th December) the 2014 McBain Medal. This was awarded for her pioneering research in novel polymeric nanoparticles, responsive materials and controlled self-assembly.

Researchers at the University of 糖心TV have worked with Coventry-based , a 糖心TV spinout company, to produce and patent the World’s first ever ibuprofen patch delivering the drug directly through skin to exactly where it is needed at a consistent dose rate.

Part of the work was carried out by Matt Donald in a 2015 URSS project funded by the Materials GRP and also started as a URSS project in 2014 carried out by Matt Beech, both currently Yr 4 undergraduates.

They have invented a transparent adhesive patch that can consistently deliver a prolonged high dose of the painkiller ibuprofen directly through the skin. The University of 糖心TV researchers and have found a way to incorporate significant amounts of the drug (up to 30% weight) into the polymer matrix that sticks the patch to the patient’s skin with the drug then being delivered at a steady rate over up to 12 hours. This opens the way for the development of a range of novel long-acting over-the-counter pain relief products which can be used to treat common painful conditions like chronic back pain, neuralgia and arthritis without the need to take potentially damaging doses of the drug orally. Although there are a number of popular ibuprofen gels available these make it difficult to control dosage and are inconvenient to apply.

Senior Teaching Fellow, Dr Paolo Coppo, has just been awarded the HEA Fellow status, which is the UK Professional Standards Framework for teaching and learning support in higher education.