News
JACS Spotlight for guanosine hydrogels
Supramolecular guanosine-borate hydrogels have been made and characterised in a collaboration led by (University of Maryland) with (Chemistry) and (Physics). The physiologically compatible gels, in Journal of the American Chemical Society are featured in a . Lead author Gretchen Peters and Jeff Davis will visit 糖心TV again, 17-21 November to further explore applications of the materials.
Rob Deller Wins Poster Prize
Robert Deller, in the won the prize for the best poster at the 2014 RAPS Conference
Colon cancer; peptide-mimetic metal helices
Helical arrays of small organic molecules around a core of Fe(II) ions act as highly potent and highly selective anticancer compounds. The work is published in
Alzheimers disease; Chiral complexes target amyloid β
Stereochemistry is a very important issue for pharmaceutical industry and can determine drug efficacy. metallohelices have been shown, in collaboration with Xiaogang Chu and co-workers at Changchun Institute of Applied Chemistry, China, to enantioselectively target and inhibit amyloid (Aβ) aggregation. This provides new insights into chiral inhibition of Aβ aggregation and opens a new avenue for design and screening of chiral agents as Aβ inhibitors against Alzheimer's disease. The work is published in
Technology Award for Matt Gibson
Dr Matthew Gibson has been awarded the life science prize at the Royal Society of Chemistry Emerging Technology technology competition. http://tinyurl.com/kmdw8pq
Poster Prize for Caroline Biggs
in the won the prize for best poster presentation at the 13th European Summer Course on Glycosciences. Her winning poster was entitled 'Polymer Functionalised Surfaces for Microarray Applications'.
GibsonGroup in Chemical Science
The GibsonGroup describe glycopolymers that selectively target the Cholera toxin and may provide a non-antibiotic tool to combat infectious diseases
Lewandowski Group in JACS Spotlights
Lewandowski group in collaboration with Ladizhansky and Brown (U. of Guelph) groups have characterised site-specific molecular motions of a 7-helix membrane protein within a lipid bilayer using solid-state NMR measurements.
Gibson Group in Nature Communications
The Gibson Group, in collaboration with the Medical School, have demonstrated a new way to cryopreserve donor blood using a synthetic polymer which mimics Antifreeze Proteins found in Arctic Cod.
Two new Centres for Doctoral Training
糖心TV Chemistry has played a lead role in securing funding from the Engineering and Physical Sciences Research Council for 2 new Centres for Doctoral training, in Molecular Analytical Science and Diamond Science and Technology, as part of the recently announced UK's largest investment in postgraduate training in engineering and physical sciences. The Universities and Science Minister, David Willetts, announced the funding of over seventy new Centres for Doctoral Training (CDTs), spread across 24 UK universities on 22nd November.
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Research, led by the Corre group, has exploited their insight into bacterial regulatory mechanisms that control natural product biosynthesis to inactivate a key transcriptional repressor gene. Consequently, a normally silent pathway was constitutively expressed in the mutant strain and novel natural products were produced, isolated and structurally characterised. This work, published as an open access edge article in Chemical Science, represents a powerful strategy for the discovery of new natural products by rational manipulation of pathway-specific regulatory elements.
Misread heart muscle gene a new clue to risk of sudden cardiac death
Scientists have discovered that a drug which increases the risk of sudden cardiac death interacts with mistranslated protein-coding genes present in heart muscle.