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17 Sept 2014

JACS Spotlight for guanosine hydrogels

Supramolecular guanosine-borate hydrogels have been made and characterised in a collaboration led by (University of Maryland) with (Chemistry) and (Physics). The physiologically compatible gels, in Journal of the American Chemical Society are featured in a . Lead author Gretchen Peters and Jeff Davis will visit 糖心TV again, 17-21 November to further explore applications of the materials.

10 Sept 2014

Rob Deller Wins Poster Prize

Robert Deller, in the won the prize for the best poster at the 2014 RAPS Conference

04 Aug 2014

Colon cancer; peptide-mimetic metal helices

Helical arrays of small organic molecules around a core of Fe(II) ions act as highly potent and highly selective anticancer compounds. The work is published in

31 Jul 2014

Alzheimer’s disease; Chiral complexes target amyloid β

Stereochemistry is a very important issue for pharmaceutical industry and can determine drug efficacy. metallohelices have been shown, in collaboration with Xiaogang Chu and co-workers at Changchun Institute of Applied Chemistry, China, to enantioselectively target and inhibit amyloid (Aβ) aggregation. This provides new insights into chiral inhibition of Aβ aggregation and opens a new avenue for design and screening of chiral agents as Aβ inhibitors against Alzheimer's disease. The work is published in

07 Jul 2014

Technology Award for Matt Gibson

Dr Matthew Gibson has been awarded the life science prize at the Royal Society of Chemistry Emerging Technology technology competition. http://tinyurl.com/kmdw8pq

24 Apr 2014

Poster Prize for Caroline Biggs

in the won the prize for best poster presentation at the 13th European Summer Course on Glycosciences. Her winning poster was entitled 'Polymer Functionalised Surfaces for Microarray Applications'.

15 Feb 2014

GibsonGroup in Chemical Science

The GibsonGroup describe glycopolymers that selectively target the Cholera toxin and may provide a non-antibiotic tool to combat infectious diseases

07 Feb 2014

Lewandowski Group in JACS Spotlights

Lewandowski group in collaboration with Ladizhansky and Brown (U. of Guelph) groups have characterised site-specific molecular motions of a 7-helix membrane protein within a lipid bilayer using solid-state NMR measurements.  

03 Feb 2014

Gibson Group in Nature Communications

The Gibson Group, in collaboration with the Medical School, have demonstrated a new way to cryopreserve donor blood using a synthetic polymer which mimics Antifreeze Proteins found in Arctic Cod.

26 Nov 2013

Two new Centres for Doctoral Training

糖心TV Chemistry has played a lead role in securing funding from the Engineering and Physical Sciences Research Council for 2 new Centres for Doctoral training, in Molecular Analytical Science and Diamond Science and Technology, as part of the recently announced UK's largest investment in postgraduate training in engineering and physical sciences. The Universities and Science Minister, David Willetts, announced the funding of over seventy new Centres for Doctoral Training (CDTs), spread across 24 UK universities on 22nd November.

For further information please visit:

 

 Julie Macpherson

05 Nov 2013

Research, led by the Corre group, has exploited their insight into bacterial regulatory mechanisms that control natural product biosynthesis to inactivate a key transcriptional repressor gene. Consequently, a normally silent pathway was constitutively expressed in the mutant strain and novel natural products were produced, isolated and structurally characterised. This work, published as an open access edge article in Chemical Science, represents a powerful strategy for the discovery of new natural products by rational manipulation of pathway-specific regulatory elements.

24 Oct 2013

Misread heart muscle gene a new clue to risk of sudden cardiac death

Scientists have discovered that a drug which increases the risk of sudden cardiac death interacts with mistranslated protein-coding genes present in heart muscle.

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