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BEGIN:VEVENT
DTSTAMP:20260506T142003Z
DTSTART;VALUE=DATE-TIME:20240606T120000
DTEND;VALUE=DATE-TIME:20240606T130000
SUMMARY:ÌÇÐÄTV Cancer Research Centre Invited Lecture: Cancer Phenotypes
  in Tumour Heterogeneity\, Drug Efficacy and Drug-Induced Dedifferentiat
 ion\, Professor Peter A. Lay\, University of Sydney
TZID:Europe/London
UID:20240606-8a1785d88f95a9d5018fc834e692570d@warwick.ac.uk
CREATED:20240530T063421Z
DESCRIPTION:Abstract: Solid cancer tumours are a heterogeneous mixture of
  cancer cell phenotypes and other cells\, which all have a role in the p
 rogression of the disease. Cancer cells will change their phenotype in r
 esponse to environmental factors depending on whether they are mainly in
 volved in tumour growth (proliferation) or cancer invasion and spread (m
 etastases). We will discuss what factors are important in changing pheno
 type and how cancer cells send and receive message to change cell phenot
 ypes of other cancer cells and non-cancer cells that can lead to tissue 
 wasting. We will discuss the roles of metal based drugs\, Pt\, Ru\, Ga\,
  In\, on different cancer phenotypes and potential immunogenic responses
 \, including the ability of certain drugs to convert aggressive metastat
 ic phenotypes to non-aggressive phenotypes through irreversible dediffer
 entiation prior to exerting a cytotoxic effect\, which then has the pote
 ntial to improve drug treatment. Examples of these effects will be given
  for triple negative breast cancer cells\, ovarian cancer cells and also
  the potential for biospectroscopies for rapid phenotyping of cancers fo
 r personalised treatments. Biography: Professor Peter A. Lay completed t
 heir BSc(Hon1) from the University of Melbourne in 1977 and received his
  PhD from the Australian National University in 1981. He was a CSIRO Pos
 tdoctoral Fellow (1981–1984) at Stanford University and CSIRO\, and a QE
 II Fellow (1984–1985) at Deakin University. He was appointed as a Lectur
 er in Inorganic Chemistry (1985) at the University of Sydney and became 
 a full Professor in 1997 and was twice awarded Australian Research Counc
 il Professorial Fellows. He is currently an Emeritus Professor of Chemis
 try at the University of Sydney and a Fellow of the Australian Academy o
 f Science (AAS) and the Royal Society of New South Wales. He was awarded
  the David Craig Medal (Chemistry) of the AAS and a Lifetime Achievement
  Award for Synchrotron Science (AS) by ANSTO (the operators of the Austr
 alian Synchrotron. He was Chair of the Committee for the design and cons
 truction of the new MEX (medium-energy XAS) beamlines at the (AS) and ha
 s contributed to committees and symposia on the conceptual design and co
 nstruction of new XAS and XFM beamlines at the CLS\, APS and SSRL. His r
 esearch is in bio-inorganic chemistry\, inorganic medicinal chemistry an
 d biomedical applications of vibrational spectroscopy and synchrotron sc
 ience. https://www.sydney.edu.au/science/about/our-people/academic-staff
 /peter-lay.html
LOCATION:MRI\, SLS
URL:
ATTACH:
CATEGORIES:BiomedicalSciences
LAST-MODIFIED:20240530T063421Z
ORGANIZER;CN=Jas Bains:
END:VEVENT
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