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BEGIN:VEVENT
DTSTAMP:20260507T034932Z
DTSTART;VALUE=DATE-TIME:20231017T120000
DTEND;VALUE=DATE-TIME:20231017T130000
SUMMARY:SLS and WMS Microbiology and Infectious Diseases Seminar: L-form 
 switching as a mechanism for antibiotic evasion\, Dr Katarzyna Mickiewic
 z\, University of Newcastle
TZID:Europe/London
UID:20231017-8a1785d888d8098e0188e7b009da0433@warwick.ac.uk
CREATED:20231006T122758Z
DESCRIPTION:tract: My research focuses on an understudied mechanism of an
 tibiotic evasion\, called L-form switching. This process involves a tran
 sient loss of bacterial protective layer\, called the cell wall\, in res
 ponse to antibiotics\, which target this structure (for example penicill
 in). Without their wall\, bacteria are susceptible to bursting and slow 
 growing\, but they can survive. Once antibiotics are gone\, bacteria can
  rebuild the wall and resume rapid growth. Importantly\, many pathogens\
 , including E. coli and S. aureus\, can undergo L-form switching and it 
 has been implicated in several recurrent diseases\, such as sepsis\, tub
 erculosis\, mastitis\, urinary tract and gastrointestinal infections\, b
 oth in human and animals. Even though L-form switching presents a powerf
 ul strategy for antibiotic evasion\, especially in older or immunocompro
 mised individuals\, the fragile nature of L-forms and low numbers make t
 hem very difficult to study in the host body. Therefore\, L-form switchi
 ng in the context of the host and its impact on recurrent infection are 
 currently poorly understood. In my talk\, I will focus on my findings re
 garding the potential role of L-forms in recurrent infections and descri
 be future directions of my research. See upcoming talks: https://warwick
 .ac.uk/fac/sci/lifesci/intranet/staffpg/diary/mids
LOCATION:A042\, Medical School Building
CATEGORIES:BiomedicalSciences,DivisionalSeminars,SLS/WMS Microbiology and
  Infectious Disease seminar
LAST-MODIFIED:20231006T122758Z
ORGANIZER;CN=Jas Bains:
END:VEVENT
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