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BEGIN:VEVENT
DTSTAMP:20260508T173006Z
DTSTART;VALUE=DATE-TIME:20220720T130000
DTEND;VALUE=DATE-TIME:20220720T140000
SUMMARY:CANCELLED - BMS Seminar: Visualising chromatin replication one mo
 lecule at a time\, Dr Hasan Yardimci\, The Francis Crick Institute
TZID:Europe/London
UID:20220720-8a1785d77e9c0080017e9fde8ade43d2@warwick.ac.uk
CREATED:20220719T084009Z
DESCRIPTION:Abstract: Accurate DNA replication is performed by the multi-
 protein replisome complex and is tightly regulated in eukaryotic cells t
 o ensure genome stability. A major focus of our group is to elucidate ho
 w the replisome overcomes nucleoprotein complexes\, which is necessary f
 or normal replication fork progression. To gain insight into how the rep
 lisome complex deals with natural impediments in a physiologically relev
 ant environment\, we study replication in Xenopus laevis egg extracts. U
 sing fluorescently labelled proteins\, we are investigating the fate of 
 parental histones\, inactive Mcm2-7 complexes\, and cohesin complexes up
 on replication fork collision. The ability to record molecular movies of
  these encounters with single-molecule sensitivity is giving us access i
 nto molecular details that are difficult to gain by ensemble methods. Bi
 ography: Dr Hasan Yardimci obtained a BSc degree in physics from Bogazic
 i University\, Turkey\, in 1999. He then joined the graduate program of 
 Johns Hopkins University and received his PhD in soft condensed matter p
 hysics in 2006. As a postdoctoral research fellow at University of Illin
 ois at Urbana-Champaign (2006-2008)\, Hasan studied the molecular mechan
 ism of a mitotic kinesin using single molecule imaging methods. He then 
 moved to Harvard Medical School (2008-2013) as a postdoc\, where he focu
 sed on single molecule studies of eukaryotic DNA replication. In 2013\, 
 Hasan established his own research group at Clare Hall Laboratories\, Ca
 ncer Research UK London Research Institute (now part of the Francis Cric
 k Institute). His laboratory develops and applies novel single molecule 
 tools to study DNA replication and repair.
LOCATION:IBRB Lecture Theatre and MS Teams
CATEGORIES:BiomedicalSciences,DivisionalSeminars
LAST-MODIFIED:20220719T084009Z
ORGANIZER;CN=Jas Bains:
END:VEVENT
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