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BEGIN:VEVENT
DTSTAMP:20260513T015937Z
DTSTART;VALUE=DATE-TIME:20200130T123000
DTEND;VALUE=DATE-TIME:20200130T133000
SUMMARY:BMS Seminar at CSRL: Development of new therapeutic strategies fo
 r endometriosis\, Professor Kanako Hayashi\, Associate Professor\, Depar
 tment of Obstetrics and Gynecology\, Southern Illinois University School
  of Medicine\, Japan
TZID:Europe/London
UID:20200130-8a17841a6fc768ea016fe79d36fc174c@warwick.ac.uk
CREATED:20200127T153458Z
DESCRIPTION:Abstract: Kanako has extensive experience in gynecological di
 seases including endometriosis and ovarian/endometrial cancer\, uterine 
 biology and reproductive toxicology. Furthermore\, she has a good track 
 record for leadership of research teams\, which are necessary to success
 fully carry out the proposed study. Kanako\, also has a broad background
  in cellular\, molecular\, genetic and epigenetic techniques to understa
 nd etiology and mechanisms of the diseases using animal models\, primary
  human tissues and cells\, and data sets from the public sources. Also e
 xpertise in the targetable signaling mechanisms for developing therapeut
 ic strategies. For example\, we have published our findings in Oncogene 
 2015 and Biol Reprod 2016 and 2018. In those studies\, we have found not
  only the signaling mechanisms of the disease but also therapeutic targe
 t(s) by small molecule(s) in the signaling pathway. Recently\, the team 
 and Union Therapeutics A/S in Denmark have agreed to further develop nic
 losamide for clinical use for treatment of endometriosis through a licen
 sing agreement. The first clinical trial has been planned and pre-clinic
 al pharmacokinetics and toxicokinetics studies for future phase II and I
 II trials are currently ongoing. Thus\, we have been successfully expand
 ing potential therapeutic drugs in a pre-clinical setting to clinical tr
 anslational research. In addition\, laying the groundwork for the resear
 ch by developing necessary animal and cell culture models. In the past\,
  we have developed a new mouse model to examine and understand etiology 
 of endometrial cancer. Together these studies have been well received\, 
 and as a result\, in 2014 Kanako was named the recipient of New Investig
 ator Award from The Society for the Study of Reproduction\, and has succ
 essfully collaborated with many topnotch researchers and produced severa
 l peer-reviewed publications from each project
LOCATION:CSRL Seminar Room\, CSB\, UHCW
CATEGORIES:BiomedicalSciences,DivisionalSeminars,CSRL
LAST-MODIFIED:20200127T153458Z
ORGANIZER;CN=Jas Bains:
END:VEVENT
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