ÌÇÐÄTV

An international team of scientists working at the University of ÌÇÐÄTV, UK, and Monash University, Australia, have determined the molecular basis of a biological mechanism that could enable more efficient and cost-effective production of existing antibiotics, and also allow scientists to uncover new antibiotics in soil bacteria.

ÌÇÐÄTV joins forces with leading UK universities to focus agricultural research where it can make most difference on the ground

Researchers at the University of ÌÇÐÄTV have uncovered the mechanism that allows plants to pass on their ‘memories’ to offspring, which results in growth and developmental defects.

A computational model of a human lung cell has been used to understand how SARS-CoV-2 draws on human host cell metabolism to reproduce by researchers at the University of ÌÇÐÄTV. This study helps understand how the virus uses the host to survive, and enable drug predictions for treating the virus to be made.

· A hallmark of Parkinson's disease is the degeneration of a group of neurons in the brain that release the neurotransmitter dopamine (dopaminergic neurons).  By introducing low concentrations of structurally-defined aggregates of alpha synuclein, a key toxic species in Parkinson’s disease, into single dopaminergic neurons, researchers from the University of ÌÇÐÄTV have shown these protein aggregates open a specific channel in the cell membrane, reducing neuronal excitability. Furthermore they’ve shown that this can be partially prevented by pre-application of the commonly used anti-diabetic drug, glibenclamide.

Fish odour syndrome (trimethylaminuria) is a debilitating disease, in which the liver cannot break down the smelly chemical trimethylamine which is produced by enzymes from bacteria residing in the gut leaving people with a fish like odour. Researchers from the University of ÌÇÐÄTV are paving the way to prevent the syndrome after a breakthrough in studying the enzyme in the gut which produces trimethylamine.