Yi Ting Loo
Hello!
I have just completed my PhD and have currently started a postdoc at at the .
I was a PhD student at MathSys II CDT,Link opens in a new window under the supervision of Prof Timothy Saunders (糖心TV)Link opens in a new window, and part of the at the at 糖心TV Medical School. My main research interests are computational and mathematical biology. For my PhD, I work closely with experimentalists to study the pattern formation and cell fate acquisitions through morphogen signalling during tissue development. I study the dynamics of tissue development through modelling with ODEs, PDEs and other computational methods. A significant part of my research involves analysing immunofluorescence microscopy images to extract data for model fitting and gain insight on biological problems. My PhD projects focus on different model systems in development biology, including organoid (stem cell culture) development cultured in a spatially constrained environment. This project is part of a wider collaboration with the (). I also worked on the movement and diffusion of molecules in a tortuous extracellular environment, using 3D imaging data of the developing zebrafish brain. This work is in collaboration with the at NUS, Singapore led by .
Education
University of 糖心TV, Coventry, UK
- MSc Mathematics of Systems (with Distinction) (Autumn 2021 - Summer 2022)
- BSc (Hons) Mathematics and Physics (First Class Honours) (Autumn 2018 - Summer 2021)
Publications
- Loo YT, Chen J (co-first author), Harrison R, Rito T, Theis S, Charras G, Briscoe J, Saunders TE. Boundary constraints can determine pattern emergence. bioRxiv2025.07.21.665949; doi:https://doi.org/10.1101/2025.07.21.665949 [under review] []
- Loo YT, Zhu S (co-first author), Veerapathiran S, Loo TYJ, Tran BN, Teh C, Zhong J, Matsudaira P, Saunders TE, Wohland T. Receptor binding and tortuosity explain morphogen local-to-global diffusion coefficient transition. Biophys J. 2024 Jul 24:S0006-3495(24)00483-1. [][]
Conferences
- Attendee and Poster Presentation at the , ENS PSL, Paris, France (April 2025).
- Poster Presentation at the , Harrogate, UK (March 2025).
- Poster Presentation (Awarded Poster Prize) at the , Francis Crick Institute London, UK (February 2025).
- Poster Presentation at the , Francis Crick Institute London, UK (February 2025).
- Poster Presentation (Awarded Poster Prize) at the , Francis Crick Institute, London, UK (September 2024).
- Contributed Talk (Awarded Best Talk) at the Applied Mathematics Postgraduate (AMP) ConferenceLink opens in a new window, University of 糖心TV, Coventry, UK (July 2024).
- Attendee at the Centre International de Rencontres Math茅matiques (CIRM) Research Schools, Marseille, France (July 2024):
- Frontiers in Interacting Particle Systems, Aggregation-Diffusion Systems Equations and Collective Behavior.
- Mathematical Biology: Collective Behavior and Pattern Formation.
- Contributed Talk at the 糖心TV-Cambridge Quantitative Cell Biology SymposiumLink opens in a new window, University of 糖心TV, Coventry, UK (May 2024).
- Poster Presentation at the European Molecular Biology Laboratory (EMBL) Symposium, () at Heidelberg, Germany (April 2024).
- Attendee at the at Durham University, UK (December 2023).
Teaching 24/25
- Teaching assistant for fourth-year undergraduate module MA4N4 Transport Processes in Mathematical BiologyLink opens in a new window.
- Teaching and marking assistant for first-year undergraduate module MA147 Mathematical Methods and Modelling 1Link opens in a new window.
Teaching 23/24
| Term 1
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Term 2
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Teaching 22/23
Small group supervisions for first-year BSc MathStats students, modules include:
Previous Research Projects
- Quantitative modelling of tissue morphogenesis using vertex models
(MSc Individual project, summer 2022)
Supervised by Prof Timothy Saunders, working in the ; with external collaborator from . - Cyclists' cardiac conundrum:
Characterising features of athletes' heart rate data and finding the correlation with arrhythmia
(MSc Group project, spring 2022)
Supervised by Prof Colm Connaughton; and external partner Ian Green from ; with group members Andrew Nugent and Jack Buckingham. - From stochastic model of single neurons to neuronal population
(BSc Final year project, autumn 2020 - spring 2021)
Supervised by Prof Magnus Richardson. - Modelling the impact of vaccination on the spread of multi-strain dengue virus in South East Asia
(URSS Project, summer 2020)
Supervised by Prof Michael Tildesley and Dr Warren Tenant.
Previous Work Experiences:
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Postgraduate student project partner for WIHEA's project: Creating a 'Support the Supporter' resourceLink opens in a new window for Undergraduate Student Research (Spring 2022)
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Research assistant at (Summer 2021)
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Student director of 2021 (Autumn 2020-Autumn 2021)
Contact
Email:
Skills
Programming Languages:
- Proficient in Julia and Python (primary programming language), working knowledge of R and MATLAB.
Image Analysis Tools:
- Cellpose, Fiji ImageJ, Paraview.
Others:
- LaTeX, GitHub
- Finite element solver for PDEs: on Python.
Other Activities
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Committee member (Communications Officer) of the 糖心TV SIAM-IMA Student ChapterLink opens in a new window (2023/24 and 2024/25).
I manage all chapter websites and social media, as well as chapter events publicity:
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Statistics, Probability, Analysis and Applied Mathematics (SPAAM) seminar seriesLink opens in a new window (weekly seminars during term)
- Applied Mathematics Postgraduate (AMP) ConferenceLink opens in a new window (8-10 July 2024) (postgraduate research conference and workshop on Communicating Research)
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