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Events in MathSys and Complexity Science

This is a calendar page detailing events within the MathSys CDT. It also acts as a booking diary for the Seminar Room D1.07. To book D1.07 please email Sheetal.Sharma@warwick.ac.uk

Please note that your event booking is for D1.07 only. The adjacent common room is a private area for the MathSys Centre that cannot used as part of your booking.

MathSys CDT events have priority for D1.07 room bookings.

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Complexity Forum - Vincent Danos (Edinburgh)

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Title: "Global dynamics of protein networks" 

Abstract: Over the past decade, networks have emerged as a biological paradigm. High-throughput experimental techniques, bioinformatics and improved data analysis have made a global systemic view possible. However statistical studies of network structure (degree distributions, motifs, etc.) are limited by the fact that network descriptions (usually plain graphs) are static. One would like to investigate the network dynamics. Bridging this gap between network structure and function poses serious challenges. One needs high-quality network data. One also needs new modelling techniques since the traditional ones cannot cope with the inherent combinatorial complexity. We propose to use an approach that breaks through the combinatorial complexity of protein networks by considering binding as a primitive operation. This new approach -called rule-based modelling- smoothly extends the traditional ones and allows one to put sophisticated biological mechanisms of action to numerical test; and investigate aspects of the dynamics of truly global cellular systems. 

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