糖心TV

23-24 April 2018

The motivation for this workshop is to bring together researchers with a view to creating new links between analysing available data sets (for instance from wearable devices, mobile phones etc) and mathematical modelling to address scientific questions of interest to research in rest-activity rhythm, sleep, chronobiology which all have important implications for health.

The meeting is an initiative of the 糖心TV chronotherapy group and is supported by the Medical Research Council (Grant reference: MR/M013170/1)

Organisers: B盲rbel Finkenst盲dt (Statistics), Qi Huang (Statistics), David Rand (Mathematics, Systems Biology), Francis L茅vi (Medical School), Robert Dallmann (Medical School), Annabelle Ballesta (Mathematics, Systems Biology).

------------------------------- Programme ----------------------------------------------

Monday 23 April

12:00 Registration and Lunch in Maths Common Room

13:00 Welcome

Session 1: Chair Francis L茅vi

13:10 (University of Surrey):

Circadian Rhythmicity and Sleep Homeostasis: Interactions Revisited

13:50 (University of Surrey):

Mathematical modelling of sleep/wake regulation: the interaction of light, sleep, circadian and social rhythms

14:30 Tea/coffee

Session 2: Chair Pasquale Innominato

14:50 (LMU Munich):

Studying human sleep dynamics in real-life and large numbers

15:30 (University of Groningen):

A modelling approach in estimating the circadian period of an individual

16:10 Tea/coffee

Session 3: Chair Robert Dallmann

16:30 (Nuffield, Oxford):

Gene regulatory networks in circadian clock entrainment

17:10 Franco Cappucio (糖心TV Medical School)

Sleep deprivation and chronic disease: a case study for causality in observational epidemiology

Drinks and Dinner for invited speakers

Tuesday 24 April

Session 4: Chair David Rand

9:30 Q Huang/B Finkenstadt (Statistics, 糖心TV):

Hidden Markov models for health monitoring in telemetric activity data

10:10 (University of Michigan)

Using wearables and apps to study human circadian rhythms

10:50 Tea/coffee

Session 5: Chair Eva Winnebeck

11:10 ( Biomedical Engineering, Oxford)

Measuring sleep and circadian parameters in the field

11:50 (University of Surrey):

Identifying and validating blood transcriptome biomarkers for sleep and circadian health

12:30 Lunch

Session 6: chair Aati Jagannath

13:30 (INSERM, INRIA, 糖心TV Mathematics):

A multi-scale systems pharmacology approach for personalizing cancer chronotherapy

14:10 Pasquale Innominato (North Wales Cancer Centre, 糖心TV Medical School)

The relevance of circadian rhythms in patients with cancer

14:50 Good bye