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Nature Communications article addresses a long-standing problem in magnetoresistance. Read more.

A UK-led international team of researchers has discovered elemental metallic copper and iron in the human brain for the first time.

Oxidative Addition of a Mechanically Entrapped C(sp)-C(sp) Bond to a Rhodium(I) Pincer Complex

By use of a macrocyclic phosphinite pincer ligand and bulky substrate substituents, researchers in the Chaplin group have demonstrated how the mechanical bond can be leveraged to promote the oxidative addition of an interlocked 1,3鈥恉iyne to a rhodium(I) center. The resulting rhodium(III) bis(alkynyl) product can be trapped out by reaction with carbon monoxide or intercepted through irreversible reaction with dihydrogen, resulting in selective hydrogenolysis of the C鈭扖 蟽鈥恇ond.

HOT article in Angew. Chem. Int. Ed.

Chemistry World Today highlights Shipman Group Research into 'Synthetic strategy exploits fluxional nitrogen to deliver three chiral centres for the price of one'

Peptide-mimetic metallohelices bind Alzheimer protein and extend life in an insect model

A collaboration between the , and groups has been published in the. The team were inspired by how small helical antifreeze proteins in Nature enable extreomophiles to survive low temperatures, where other species would not survive. Rather than using traditional peptide/protein chemistry, the team used self-assembled metallohelicates which have similar dimensions to a small alpha helix, and found some which were remarkably potent at stopping ice crystal growth ; a major technological challenge in applications from wind farms, to aircraft to cryopreservation. Modelling studies showed that the underlying activity could be linked the patches of hydrophobicity (water liking) and hydrophobicity (water hating).

Read the paper here

The have published the first Rh-catalysed arylation of fluorinated ketones in . Interestingly, we showed the difluorinated (CF₂H) ketone to be more reactive than the trifluoromethyl (CF₃) ketone, despite the fact each additional fluorine atom provides extra electronic activation.

Collaborative work from the groups of , Unwin, Rourke, and Wedge (糖心TV physics) exploring the organometallic chemistry of paramagnetic complexes of palladium(I) and platinum(I) has been published in

糖心TV Chemistry, Life Science and Medical School team up to make a new generation of readily self-assembled metallohelices kill cancer cells at very low concentration (40 nM) but have low toxicty to microbes, insects and healthy human cells.

Work performed in Richard Walton’s has been selected as a Research Highlight in the Diamond Light Source Annual Review for 2014-2015. In this work, carried out by PhD student Craig Hiley, the structures of three new metastable ruthenium oxides were determined in a collaborative project between 糖心TV and sustainable technology company Johnson Matthey. Ruthenium oxides are used in electro-catalysis for water oxidation and reduction, in heterogeneous catalysis, and are also of interest for their electronic and magnetic properties