Uganda/ Ouganda
Elimination and health economic considerations in Uganda
Uganda has had no locally transmitted cases of gHAT since 2020, and they were validated by the WHO as a country that had reached elimination as a public health problemLink opens in a new window in 2022. In January 2026, the national program is preparing their dossier to verify the status of elimination of transmissionLink opens in a new window for gHAT. However, transmission is an unobserved process which can be different from reported cases. In this context, the HAT MEPP team has performed an analysis to understand whether the last transmission event (LTELink opens in a new window) and no remaining infections (NRILink opens in a new window) have occurred, given no cases reported with continued screening since 2020. Moreover, the team considered alternative strategies for continued screening to understand the impact on any possible remaining cases as well as the costs of such strategies.
The analysis indicated that the LTE occurred before 2021 with 95% certainty, and there is only a 1% chance that a case would be reported after 2025 from those remaining infections. Our cost-effectiveness analysis indicates that no additional activities beyond the status quo are economically justified because there is a 95% chance of NRI by 2025. Counterfactual scenario analyses showed that 76.0% and 41.4% reduction in cumulative new infections and deaths, respectively, was due to vector control, and the remaining was due to intensified passive screening. The status quo will therefore continue, where screening in health facilities and reactive screening and vector control in villages where future gHAT cases occur. The cost of the status quo is expected to be $139,913鈥�$249,031 between 2026鈥�2040.
Explore all the results of the Uganda analysis in our .