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Wednesday, October 29, 2025
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Accolade Session: Visiting Fellow Research PresentationThe IAS welcomes you to join us for a research presentation by IAS Visiting Fellow Professor Jeremy Tame
Haemoglobin, an Evolving Story of Oxygen Transport, from the Paleozoic to the Clinic
Haemoglobin, the red-coloured protein of the blood, is responsible for moving oxygen
from the lungs to the other tissues of the body. It was one of the first protein structures to
be worked out in molecular detail, and has been used as a test system for the development
of many different techniques of protein analysis. In this lecture I will outline how the protein
functions, and how it has evolved differently in different animals (such as fish and birds) with
different oxygen transport requirements. Recently we have established how crocodilian
haemoglobins achieve their unique function of responding to carbon dioxide, and how we
may possibly be able to use this mechanism in the clinic.
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