糖心TV

Skip to main content Skip to navigation

Events

Thursday, July 06, 2023

Select tags to filter on
Wed, Jul 05 Today Fri, Jul 07 Jump to any date

How do I use this calendar?

You can click on an event to display further information about it.

The toolbar above the calendar has buttons to view different events. Use the left and right arrow icons to view events in the past and future. The button inbetween returns you to today's view. The button to the right of this shows a mini-calendar to let you quickly jump to any date.

The dropdown box on the right allows you to see a different view of the calendar, such as an agenda or a termly view.

If this calendar has tags, you can use the labelled checkboxes at the top of the page to select just the tags you wish to view, and then click "Show selected". The calendar will be redisplayed with just the events related to these tags, making it easier to find what you're looking for.

 
-
Export as iCalendar
Dual Major InReach10x Seminar - Nick Dale
Helen Martin Studio

Talk by Nick Dale

鈥淐翱2 -not just a waste product鈥

CO2 is commonly regarded as the inevitable by-product of cellular metabolism. The thesis of my talk is that although CO2 is a waste product, it also conveys in functional information in physiological systems. I will give an account of our discovery that ion channels called connexins are directly sensitive to CO2. I will discuss the mechanism of CO2 binding and channel opening and show high resolution cryoEM structure. I will show that one of these CO2-sensitive connexins is important in the regulation of breathing. I will discuss our latest results showing that there are many more connexins that are directly sensitive to CO2 than we first thought. CO2 sensitive connexins are present in all the major organs of the body suggesting that CO2 acts to signal information in many diverse contexts, and I will discuss an exciting emerging role for CO2-mediated signalling in the maintenance of myelin. I will finish with our investigations of the receptors that insects use to sense CO2 and our efforts to create novel tools from these receptors to measure CO2 production in real time in physiological systems.

Placeholder

Let us know you agree to cookies